Skin Care

Hessler, Jill L.

doi:10.1016/j.fsc.2015.04.002

Cited by 13 publications

(5 citation statements)

References 42 publications

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“…Efficient control of photodamage, and prevention of the ensuing premature skin aging, are some of the major issues in the development of cosmetics. Active ingredients, with UV absorbing properties to reduce the amount of radiation penetrating the skin, and those with antioxidant, anti-inflammatory, and immunomodulatory effects, are used in cosmetics and personal care products [29][30][31][32]. Ingredients that can reduce skin pigmentation, inhibit melanin biosynthesis and block the melanin-uptake by keratinocytes, are important in skin lightening and in treatment of hyperpigmentation [33][34][35].…”

Section: Discussionmentioning

confidence: 99%

Protective Effects of Salicornia europaea on UVB-Induced Misoriented Cell Divisions in Skin Epithelium

et al. 2020

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Correct orientation of cell division is extremely important in the maintenance, regeneration, and repair of continuously proliferating tissues, such as the epidermis. Regulation of the axis of division of epidermal cells prevents the apoptosis-induced compensatory proliferation, and eventually the cancer. Thus, the orientation of cell division is critical for maintaining the tissue architecture. In this study, we investigated the effects of S. europaea extract on the texture of human skin and the behavior of these cells during skin morphogenesis. In sun-exposed skin, S. europaea improved the texture. A multilayered, highly differentiated in vitro skin model indicated that, S. europaea extract suppressed the UVB-induced changes in the morphology of basal keratinocytes. Orientation of cell division was determined by measuring the axis of mitosis in the vertical sections of our experimental model. Analyses of the digital images revealed that S. europaea preserved the axis of division of basal keratinocytes from UVB-induced perturbations. Our findings uncover a new mechanism by which S. europaea responds to the spindle misorientation induced by UVB.

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Section: Discussionmentioning

confidence: 99%

Protective Effects of Salicornia europaea on UVB-Induced Misoriented Cell Divisions in Skin Epithelium

et al. 2020

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“…In addition, 46.25% of the older adults said they did not use sunscreen, one of the ways to care for the skin and protect from exposure. The fact that 26.25% of the older adults did not know what skin cancer is can justify the lack of care in relation to protection from the sun, because, in general, people are more engaged in preventive attitudes if they know about the damage and/or risks 18 . Sun exposure also causes other changes such as, for example, solar elastosis 3 which translates into increased fragmentation and porosity of the elastic fibers in the dermis 19,20 .…”

Section: Discussionmentioning

confidence: 99%

Prevalent skin and dermatoses care in older adults treated at a private clinic and its relationship with comorbidities

Mariani

Pozzi

Armond

et al. 2019

Rev. bras. geriatr. gerontol.

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Abstract Objectives : To identify and assess the prevalence of skin changes in the older adults surveyed, as well as to detect skin phototype according to the Fitzpatrick classification and to assess whether there was an association between the changes identified and predisposing factors (smoking, diabetes mellitus and hypertension). Additionally, evaluate the level of knowledge of the subjects regarding skin care. Method : A cross-sectional study was conducted in April to August 2018, based on a convenience sample of 80 older adults attending a private clinic. A questionnaire was applied among the subjects to identify their skin care and an answer sheet was completed by the researcher with information about the physical examination of the skin. Data were analyzed by the chi square or Fisher’s exact method. Poisson regression was used to determine the independent effect of the exploratory variables on the response variable. Results : The sampled population had a low level of education and was low-income and did not take proper care of their skin, while 70% were skin phototype 4. Most (73%) were aware of what skin cancer is and a significant portion 50% did not use sunscreen or moisturizer. There was no significant difference between the sexes (p>0.05). About half of the older adults reported having been instructed about skin care. Seventy two percent knew about the dangers of sun exposure. The most common skin alteration was melanosis and an association was found between diabetes and keratosis. Conclusions : The study population was low income, with a low level of education. They were exposed to the sun and did not make proper use of sunscreen or moisturizers, but sought health information from their doctor and knew what skin cancer was.

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“…Skin aging is a complex phenomenon caused by harmful factors. Intrinsic aging and photoaging are major agents leading to adverse effects on skin . Generally, these two aging processes show different characteristics.…”

Section: Discussionmentioning

confidence: 99%

Skin aging caused by intrinsic or extrinsic processes characterized with functional proteomics

et al. 2016

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The skin provides protection against environmental stress. However, intrinsic and extrinsic aging causes significant alteration to skin structure and components, which subsequently impairs molecular characteristics and biochemical processes. Here, we have conducted an immunohistological investigation and established the proteome profiles on nude mice skin to verify the specific responses during aging caused by different factors. Our results showed that UVB-elicited aging results in upregulation of proliferating cell nuclear antigen and strong oxidative damage in DNA, whereas chronological aging abolished epidermal cell growth and increased the expression of caspase-14, as well as protein carbonylation. Network analysis indicated that the programmed skin aging activated the ubiquitin system and triggered obvious downregulation of 14-3-3 sigma, which might accelerate the loss of cell growth capacity. On the other hand, UVB stimulation enhanced inflammation and the risk of skin carcinogenesis. Collectively, functional proteomics could provide large-scale investigation of the potent proteins and molecules that play important roles in skin subjected to both intrinsic and extrinsic aging.

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Skin Care

Cited by 13 publications

References 42 publications

Protective Effects of Salicornia europaea on UVB-Induced Misoriented Cell Divisions in Skin Epithelium

Protective Effects of Salicornia europaea on UVB-Induced Misoriented Cell Divisions in Skin Epithelium

Prevalent skin and dermatoses care in older adults treated at a private clinic and its relationship with comorbidities

Skin aging caused by intrinsic or extrinsic processes characterized with functional proteomics

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