Skin-friendly dressing with alcohols treatment for enhancement of mechanical and biocompatible properties

Chen, Huawei; Lin, Min-Feng; Lai, Yi-Hung; Chen, Bor-Yann

doi:10.1016/j.jtice.2021.09.038

Cited by 2 publications

(2 citation statements)

References 42 publications

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“…To accelerate the physical gelation process, alcohols can usually be introduced to induce the ß-sheet formation in silk fibroin hydrogels. [60][61][62][63][64] The polarity of the solvent plays a significant role during the gelation process of silk fibroin using the mechanism that the polar reagents use to capture water molecules from the silk molecular chains, resulting in the formation of ß-sheet nucleation sites. 53 Notably, different alcohols show diverse induction effects on fibroin gelation.…”

Section: Polar Reagentsmentioning

confidence: 99%

Silk fibroin hydrogels for biomedical applications

Zhang

et al. 2022

Smart Medicine

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Silk fibroin hydrogels occupy an essential position in the biomedical field due to their remarkable biological properties, excellent mechanical properties, flexible processing properties, as well as abundant sources and low cost. Herein, we introduce the unique structures and physicochemical characteristics of silk fibroin, including mechanical properties, biocompatibility, and biodegradability. Then, various preparation strategies of silk fibroin hydrogels are summarized, which can be divided into physical cross‐linking and chemical cross‐linking. Emphatically, the applications of silk fibroin hydrogel biomaterials in various biomedical fields, including tissue engineering, drug delivery, and wearable sensors, are systematically summarized. At last, the challenges and future prospects of silk fibroin hydrogels in biomedical applications are discussed.

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Section: Polar Reagentsmentioning

confidence: 99%

Silk fibroin hydrogels for biomedical applications

Zhang

et al. 2022

Smart Medicine

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“…However, EtOH, which is a common antiseptic and disinfectant used to clean and disinfect wounds, is not routinely used in wound dressings, given that prolonged EtOH exposure can impair the proliferative response during healing, and cause delays in epithelial coverage, collagen synthesis, and blood vessel regrowth . However, recent evidence on some of the advantages of EtOH-treated or -embedding wound dressings and scaffolds − has started to emerge. Since wound dressings with CNTs − and with antibiotics − have been widely discussed to date, both presenting important advantages for specific applications, we find it useful to investigate potential synergies between these three antibacterial agents: CNTs, EtOH, and antibiotics.…”

Section: Introductionmentioning

confidence: 99%

Antibacterial Interactions of Ethanol-Dispersed Multiwalled Carbon Nanotubes with Staphylococcus aureus and Pseudomonas aeruginosa

Asaftei,

Lucidi,

Anton

et al. 2024

ACS Omega

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Infectious diseases are acknowledged as one of the leading causes of death worldwide. Statistics show that the annual death toll caused by bacterial infections has reached 14 million, most of which are caused by drug-resistant strains. Bacterial antibiotic resistance is currently regarded as a compelling problem with dire consequences, which motivates the urgent identification of alternative ways of fighting bacteria. Various types of nanomaterials have been reported to date as efficient antibacterial solutions. Among these, carbon-based nanomaterials, such as carbon nanodots, carbon graphene oxide, and carbon nanotubes (CNTs), have been shown to be effective in killing a wide panel of pathogenic bacteria. With this study, we aim to provide additional insights into this topic of research by investigating the antibacterial activity of a specific type of multiwalled CNTs, with diameters from 50 to 150 nm, against two representative opportunistic pathogens, i.e., the Gram-positive bacterium Staphylococcus aureus and the Gramnegative bacterium Pseudomonas aeruginosa, both included among the top antibiotic-resistant pathogens. We also test the synergistic effect of CNTs with different antibiotics commonly used in the treatment of infections caused by S. aureus and/or P. aeruginosa. Additionally, a novel approach for quantitatively analyzing bacterial aggregation in brightfield microscopy images was implemented. This method was utilized to assess the effectiveness of CNTs, either alone or in combination with antibiotics, in dispersing bacterial aggregates. Finally, atomic force microscopy coupled with a newly devised image analysis pipeline was used to examine any potential morphological changes in bacterial cells following exposure to CNTs and antibiotics.

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Skin-friendly dressing with alcohols treatment for enhancement of mechanical and biocompatible properties

Cited by 2 publications

References 42 publications

Silk fibroin hydrogels for biomedical applications

Silk fibroin hydrogels for biomedical applications

Antibacterial Interactions of Ethanol-Dispersed Multiwalled Carbon Nanotubes with Staphylococcus aureus and Pseudomonas aeruginosa

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