Skin whitening activity of supercritical fluid extract from spent coffee in B16F10 melanoma cell

Sung, Hea Mi; Jung, Hyun Jung; Sin, Ji Sun; Kim, Ki Myong; Wee, Ji‐Hyang

doi:10.1007/s10068-015-0139-3

Cited by 7 publications

(10 citation statements)

References 20 publications

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“…The results also yielded evidence of eicosenoic, behenic, and lignoceric acids that were present at below 1% of the oil. The results are in agreement with those reported by Sung et al (2015) on Vietnamese coffee. [8] It is noted that studies conducted by Jenkins et al (2014) and Dang and Nguyen (2019) indicated fatty acid composition of SCG obtained from Vietnamese coffee was different with respect to weight percentages of palmitic, oleic, and linoleic acids.…”

Section: Oil Content and Fatty Acid Compositionsupporting

confidence: 93%

“…[3][4][5][6][7] Spent coffee ground is also used for development of skin-whitening products due to its inhibition of tyrosinase activity and melanin synthesis. [8,9] Sufficient amounts of dietary fiber, protein, lipid, and low glycemic sugars in SCG and acceptable rheological properties of SCG-supplemented dough give rise to its application in biscuit products. [10] In addition, SCG reportedly contains a wide variety of bioactive constituents that can be exploited as a nutraceutical or used in food products.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of fatty acids, phenolics and bioactivities of spent coffee grounds prepared from Vietnamese coffee

Huynh

et al. 2021

International Journal of Food Properties

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Spent coffee ground (SCG) is a residue released during coffee brewing. Disposal of SCG is able to lead to a loss of bioactive constituents and have a negative impact upon the environment. This study aimed to explore fatty acids, bioactive phenolics, antioxidant and anti-aging potentials of SCG samples obtained from coffee shops in Ho Chi Minh city, Vietnam. The oil content of the SCG samples ranged from 6.3 to 10.5%, and linoleic (43%), palmitic (33.4%) and oleic (11%) acids were identified as major constituents of the oil. Chlorogenic acid was the most abundant phenolic acid examined (832.9-7657.7 μg/g of dry weight), followed by ferulic acid (40.5-1041.7 μg/ g). Through anti-collagenase and anti-elastase assays, SCG showed a promising anti-aging activity, with IC 50 values comparable with those of epigallocatechin gallate. The correlation analysis revealed gallic acid positively correlated with the free radical scavenging potential evaluated by DPPH (2,2-diphenyl-1-picrylhydrazyl) assay and the inhibitory effect on elastase. The results demonstrated that utilization of SCG prepared from Vietnamese coffee could open new avenues for food and cosmeceutical industry.

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Section: Oil Content and Fatty Acid Compositionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Evaluation of fatty acids, phenolics and bioactivities of spent coffee grounds prepared from Vietnamese coffee

Huynh

et al. 2021

International Journal of Food Properties

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“…The previous study has shown that the SFC from spent coffee exhibited significantly high activities in the inhibition of melanin synthesis and tyrosinase activity [ 14 ], which is in accordance with our results. The authors concluded that high fatty acid content did not correspond with the capacity to inhibit melanin synthesis or tyrosinase activity.…”

Section: Discussionsupporting

confidence: 93%

“…The inhibitory effects of spent coffee grounds SFE on melanogenesis were reported by Sung et al [ 14 ]. However, the action mechanisms of spent coffee grounds for depigmentation still remained to be elucidated.…”

Section: Introductionmentioning

confidence: 68%

Supercritical Fluid Extract of Spent Coffee Grounds Attenuates Melanogenesis through Downregulation of the PKA, PI3K/Akt, and MAPK Signaling Pathways

Huang

Wei

Siao

et al. 2016

Evidence-Based Complementary and Alternative Medicine

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The mode of action of spent coffee grounds supercritical fluid CO2 extract (SFE) in melanogenesis has never been reported. In the study, the spent coffee grounds were extracted by the supercritical fluid CO2 extraction method; the chemical constituents of the SFE were investigated by gas chromatography-mass spectrometry (GC-MS). The effects of the SFE and its major fatty acid components on melanogenesis were evaluated by mushroom tyrosinase activity assay and determination of intracellular tyrosinase activity and melanin content. The expression level of melanogenesis-related proteins was analyzed by western blotting assay. The results revealed that the SFE of spent coffee grounds (1–10 mg/mL) and its major fatty acids such as linoleic acid and oleic acid (6.25–50 μM) effectively suppressed melanogenesis in the B16F10 murine melanoma cells. Furthermore, the SFE decreased the expression of melanocortin 1 receptor (MC1R), microphthalmia-associated transcription factor (MITF), tyrosinase, tyrosinase-related protein-1 (TRP-1), and tyrosinase-related protein-2 (TRP-2). The SFE also decreased the protein expression levels of p-JNK, p-p38, p-ERK, and p-CREB. Our results revealed that the SFE of spent coffee grounds attenuated melanogenesis in B16F10 cells by downregulation of protein kinase A (PKA), phosphatidylinositol-3-kinase (PI3K/Akt), and mitogen-activated protein kinases (MAPK) signaling pathways, which may be due to linoleic acid and oleic acid.

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“…Besides, stearic and oleic acid are found to be present in the oil, at the levels of 10 and 15 g/g, respectively. The results are in agreement with prior research on Vietnamese coffee by Sung et al (2015) (Sung, Jung, Sin, Kim, & Wee, 2015). Linoleic acid is a polyunsaturated fatty acid found abundantly in vegetable oil.…”

Section: Fatty Acidssupporting

confidence: 92%

Spent coffee grounds collected in Ho Chi Minh city: A good source of phenolic acids and fatty acids

2021

EJS

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Coffee is among the favorite drinks in Vietnam and many other countries. Production and consumption of coffee have released a huge amount of spent coffee ground. This study aimed to determine phenolic acids and fatty acids of spent coffee grounds collected in Ho Chi Minh city and how phenolic acid profile was affected by different environmentally friendly extractants. The results showed that average level of chlorogenic acid in ethanol/water extracts (840.4 779.9g/g) was significantly higher compared to water extracts (300.0g/g). Furthermore, the average total level of phenolic acids in ethanol/water extracts (1215.3g/g dry weight) was greater than that in the water extracts (779.9g/g dry weight). This indicated that ethanol/water outperformed water in regard to extraction of phenolic acids in the spent coffee grounds. Oil extracted from the spent coffee grounds was rich in linoleic acid (61g/g) and palmitic acid (47g/g). The findings of our study showed that the spent coffee grounds originating in Vietnam are a good source of phenolic acids and polyunsaturated fatty acids that could be utilized for food and nutraceutical production.

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Skin whitening activity of supercritical fluid extract from spent coffee in B16F10 melanoma cell

Cited by 7 publications

References 20 publications

Evaluation of fatty acids, phenolics and bioactivities of spent coffee grounds prepared from Vietnamese coffee

Evaluation of fatty acids, phenolics and bioactivities of spent coffee grounds prepared from Vietnamese coffee

Supercritical Fluid Extract of Spent Coffee Grounds Attenuates Melanogenesis through Downregulation of the PKA, PI3K/Akt, and MAPK Signaling Pathways

Spent coffee grounds collected in Ho Chi Minh city: A good source of phenolic acids and fatty acids

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