Sleep disordered breathing and subjective excessive daytime sleepiness in relation to the risk of motor vehicle crash: the Toon Health Study

Matsuo, Ryotaro; Tanigawa, Takeshi; Tomooka, Kiyohide; Ikeda, Ai; Wada, Hiroo; Maruyama, Koutatsu; Saito, Isao

doi:10.1038/s41598-020-74132-7

Cited by 7 publications

(3 citation statements)

References 28 publications

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“…This study was conducted as part of the Toon Health Study, which is a community-based prospective cohort study to characterize the risk factors for CVD in Toon City, Ehime Prefecture, Japan [26][27][28] . In this study, we recruited participants from approximately 22,000 residents of Toon City aged ≥ 30-＜80 years using direct invitations, newspaper advertisements, and posters.…”

Section: Study Subjectsmentioning

confidence: 99%

Longitudinal Changes in Arterial Stiffness Associated with Physical Activity Intensity: The Toon Health Study

Matsuo,

Ikeda,

Tomooka

et al. 2024

JAT

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Aims: Several studies have revealed an association between moderate-to-vigorous physical activity (MVPA) and arterial stiffness, which is a known risk factor for cardiovascular disease. However, a few studies have considered the difference in the longitudinal effect of its intensity in a large general population. Therefore, we examined the effect of MVPA intensity on longitudinal changes in arterial stiffness. Methods:We conducted a prospective cohort study involving 1,982 Japanese men and women. Arterial stiffness was measured using the cardio-ankle vascular index (CAVI) at baseline and 5-year follow-up. Physical activity was quantified using the Japan Arteriosclerosis Longitudinal Study Physical Activity Questionnaire and categorized into quartiles as MVPA levels. Linear mixed models were used to examine the differences at baseline and the rate of changes in CAVI associated with MVPA levels for over 5 years. Results:The multivariable-adjusted mean differences in CAVI at baseline were significantly lower in the third (β = −0.019 [95% confidence interval {CI}=−0.033 to −0.005]) and fourth (β=−0.018 [95% CI=−0.035 to −0.001]) quartiles of the MVPA group compared with those in the lowest quartile of MVPA, and the significant effect persisted 5 years later. Conclusions:In summary, this study provides evidence to support the existence of a threshold for beneficial levels of MVPA in the prevention of arterial stiffness. Furthermore, this study suggests that exceeding this threshold may exert similar effects on arterial stiffness. These findings suggest that an optimal level of MVPA exists for preventing arterial stiffness, and exceeding this threshold may not engender additional benefits.

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Section: Study Subjectsmentioning

confidence: 99%

Longitudinal Changes in Arterial Stiffness Associated with Physical Activity Intensity: The Toon Health Study

Matsuo,

Ikeda,

Tomooka

et al. 2024

JAT

Self Cite

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“…[9][10][11] EDS symptoms are associated with lower cognitive function and quality of life. [12][13][14][15] And individuals with EDS symptoms were more likely to develop disability and mortality than those without these symptoms. 16 In adolescents, EDS symptoms may negatively impact academic performance and individual developments, leading to a higher unemployment rate and a lower income level in the future.…”

Section: Introductionmentioning

confidence: 99%

Excessive Daytime Sleepiness and Insomnia Symptoms in Adolescents With Major Depressive Disorder: Prevalence, Clinical Correlates, and the Relationship With Psychiatric Medications Use

Shi,

Li,

Chen

et al. 2023

Psychiatry Investig

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Objective Excessive daytime sleepiness (EDS) and insomnia symptoms are common in patients with major depressive disorder (MDD), which might lead to a poor prognosis and an increased risk of depression relapse. The current study aimed to investigate the prevalence, and sociodemographic and clinical correlates of EDS and insomnia symptoms among adolescents with MDD.Methods The sample of this cross-sectional study included 297 adolescents (mean age=15.26 years; range=12–18 years; 218 females) with MDD recruited from three general and four psychiatric hospitals in five cities (Hefei, Bengbu, Fuyang, Suzhou, and Ma’anshan) in Anhui Province, China between January and August, 2021. EDS and insomnia symptoms, and clinical severity of depressive symptoms were assessed using Epworth sleepiness scale, Insomnia Severity Index, and Clinical Global Impression-Severity.Results The prevalence of EDS and insomnia symptoms in adolescents with MDD was 39.7% and 38.0%, respectively. Binary logistic regression analyses showed that EDS symptoms were significantly associated with higher body mass index (odds ratio [OR]=1.097, 95% confidence interval [CI]=1.027–1.172), more severe depressive symptoms (OR=1.313, 95% CI=1.028–1.679), and selective serotonin reuptake inhibitors use (OR=2.078, 95% CI=1.199–3.601). And insomnia symptoms were positively associated with female sex (OR=1.955, 95% CI=1.052–3.633), suicide attempts (OR=1.765, 95% CI=1.037–3.005), more severe depressive symptoms (OR=2.031, 95% CI=1.523–2.709), and negatively associated with antipsychotics use (OR=0.433, 95% CI=0.196–0.952).Conclusion EDS and insomnia symptoms are common among adolescents with MDD. Considering their negative effects on the clinical prognosis, regular screening and clinical managements should be developed for this patient population.

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“…2,3 Daytime sleepiness is often prioritized due to immediate safety risks, as individuals with untreated OSA are 243% more likely to have a motor vehicle accident than drivers without OSA. [4][5][6] In addition to excessive daytime sleepiness 7 and increased risk of motor vehicle accidents, 5,8 untreated OSA is associated with additional adverse daytime symptoms including impaired cognitive performance, [9][10][11] and mood disturbances. [12][13][14] It is also associated with negative health consequences, including cardiovascular disease and hypertension, 15,16 diabetes, [17][18][19] stroke, 20,21 and death.…”

Section: Introductionmentioning

confidence: 99%

Personalized and Patient-Centered Strategies to Improve Positive Airway Pressure Adherence in Patients with Obstructive Sleep Apnea

Watach¹,

Hwang²,

Sawyer³

2021

PPA

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Obstructive sleep apnea (OSA), a common sleep disorder characterized by repeated pauses in breathing during sleep, is effectively treated with positive airway pressure (PAP) therapy. The magnitude of improvements in daily functioning and reduced negative health risks are dependent on maintaining PAP adherence, which is a significant challenge. Evidence-based interventions to improve PAP use are not easily translated to clinical practice because they are labor-intensive and require specialty expertise. Further, to date, individualized care, inclusive of personalized medicine and patient-and person-centered care have been marginally incorporated in the field's understanding of OSA and PAP adherence. This integrative review describes current PAP adherence assessment processes, interventions to improve adherence, and outlines future opportunities to advance the field, particularly as it relates to individualizing care and the use of implementation science to apply evidence to practice.

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Sleep disordered breathing and subjective excessive daytime sleepiness in relation to the risk of motor vehicle crash: the Toon Health Study

Cited by 7 publications

References 28 publications

Longitudinal Changes in Arterial Stiffness Associated with Physical Activity Intensity: The Toon Health Study

Longitudinal Changes in Arterial Stiffness Associated with Physical Activity Intensity: The Toon Health Study

Excessive Daytime Sleepiness and Insomnia Symptoms in Adolescents With Major Depressive Disorder: Prevalence, Clinical Correlates, and the Relationship With Psychiatric Medications Use

Personalized and Patient-Centered Strategies to Improve Positive Airway Pressure Adherence in Patients with Obstructive Sleep Apnea

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