Sleep, physical activity, and sedentary behaviors as factors related to depression and health-related quality of life among older women living alone: a population-based study

Jang, Soyoung; Yang, Eunjin

doi:10.1186/s11556-023-00314-7

Cited by 5 publications

(2 citation statements)

References 37 publications

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“…The above is especially important because physical exercise can be used as a non-pharmacological tool to optimize sleep quality in this population. In addition, the practice of physical exercise contributes to improving sleep quality by improving mental health [ 49 ]. In fact, we observed that participants in our work with affective dysfunction (anxiety/depression) tended to be less physically active and that students with greater symptoms of anxiety and depression showed poorer sleep quality.…”

Section: Discussionmentioning

confidence: 99%

Increased Salivary IL-1 Beta Level Is Associated with Poor Sleep Quality in University Students

Ballestar-Tarín,

Ibáñez-del Valle,

Mafla-España

et al. 2023

Diseases

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Poor sleep quality is a major public health concern for all ages. In particular, university students often face stress levels and changes in social life habits that negatively influence their quality of sleep. This could be associated with psychological well-being in terms of anxiety and depressive symptoms, stress levels, and a poor self-perceived health status. The increases in the pro-inflammatory cytokine interleukin 6 (IL-6), IL-1 beta (IL-1β), and tumor necrosis factor alpha (TNFα), in blood have been linked to poor sleep quality in many diseases, but data on salivary cytokine levels in students are missing or are seldom analyzed. In this study we determined the quality of sleep in a sample of university students and the role of psychological assessment and factors affecting sleep (alcohol intake, tobacco, consumption of stimulant drinks, exercise, and body mass index). We also aimed to shed new light on the associations between sleep quality and salivary inflammatory cytokines (IL-1β, IL-6, and TNFα). Sleep quality was measured with the Athens Insomnia Scale (AIS) and Pittsburgh Sleep Quality Index (PSQI). Perceived stress was assessed using Cohen’s Perceived Stress Scale (PSS), and the Goldberg Anxiety and Depression Scale (GADS) was used to assess the level of anxiety or depression. Perceived health status was measured with a visual analogue. Saliva samples was taken in the morning and the inflammatory cytokines was measured via enzyme-linked immunoassay. There was a direct and significant association between the salivary IL-1β concentration and AIS score (r = 0.248; p = 0.038, Pearson correlation) and Pittsburgh scale score (r = 0.274; p = 0.022, Pearson correlation). The relationship between IL-1β and AIS controlling for sex, age, and chronic disease, is still significant (r = 0.260; p = 0.033). The relationship between IL-1β and PSQI controlling for the influence of these variables is also significant (r = 0.279; p = 0.022). Salivary IL-1β concentrations were not significantly associated with any of the scores of the other psychological assessments (PSS, anxiety, depression symptoms, or self-perceived health). Salivary TNFα was significantly and inversely associated with self-perceived health (r = −0.259; p = 0.033, Pearson correlation), but the salivary IL-6 concentration was not associated with any of the sleep quality scale or psychological assessment scores. Our results provide a novel relationship between pro-inflammatory cytokine IL-1β in saliva and poor sleep quality. However, the role of inflammation in poor sleep quality requires further study to identify strategies that could lower inflammation and thus, likely improve sleep quality.

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Section: Discussionmentioning

confidence: 99%

Increased Salivary IL-1 Beta Level Is Associated with Poor Sleep Quality in University Students

Ballestar-Tarín,

Ibáñez-del Valle,

Mafla-España

et al. 2023

Diseases

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“…Therefore, females, living alone and being older may likely have poorer sleep quality [ 31 ]. Scholars have pointed out that sleep quality was associated with depression, especially in elderly women living alone [ 32 ]. Other studies have also demonstrated the impact of sleep quality on depression [ 33 – 35 ].…”

Section: Introductionmentioning

confidence: 99%

The relationship between living alone or not and depressive symptoms in older adults: a parallel mediation effect of sleep quality and anxiety

Huang,

Liu,

Liang

et al. 2023

BMC Geriatr

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Background With modernization and ageing in China, the population of older adults living alone is increasing. Living alone may be a potential risk factor for depressive symptoms. However, no parallel mediation model analysis has investigated the mediating factors for living alone or not (living arrangements) and depressive symptoms. Methods This cross-sectional study included a total number of 10,980 participants from the Chinese Longitudinal Healthy Longevity Survey (CLHLS), 1699 of whom lived alone and 9281 of whom did not live alone. Binary logistic regression and parallel mediation effect model were used to explore the relationship between living alone or not and depressive symptoms and possible mediation effects. Bootstrap analysis was used to examine the mediation effect of living alone or not on depressive symptoms. Results Compared to the participants who were not living alone, the living alone group had a higher rate of depressive symptoms. The binary logistic regression showed that after adjusting for other covariates, the risk of depressive symptoms was approximately 0.21 times higher for living alone compared to not living alone (OR = 1.21, 95% CI: 1.06, 1.37). Further, the results of the bootstrap analysis supported the partial mediating role of sleep quality and anxiety. Mediation analysis revealed that sleep quality and anxiety partially mediate the relationship between living alone and depressive symptoms (β = 0.008, 95% CI [0.003, 0.014]; β = 0.015, 95% CI [0.008, 0.024], respectively). Conclusions Sleep quality and anxiety were identified as partially parallel mediators between living alone or not and depressive symptoms. Older adults living alone with poorer sleep quality and more pronounced anxiety were positively associated with higher levels of depressive symptoms. Older adults living alone should be encouraged to engage in social activities that may improve sleep quality, relieve anxiety, and improve feelings of loneliness caused by living alone. Meanwhile, older adults living alone should receive attention and support to alleviate their depressive symptoms.

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The association of living alone and social isolation with sarcopenia: A systematic review and meta-analysis

Yang,

Huang,

Yang

et al. 2023

Ageing Research Reviews

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Sleep, physical activity, and sedentary behaviors as factors related to depression and health-related quality of life among older women living alone: a population-based study

Cited by 5 publications

References 37 publications

Increased Salivary IL-1 Beta Level Is Associated with Poor Sleep Quality in University Students

Increased Salivary IL-1 Beta Level Is Associated with Poor Sleep Quality in University Students

The relationship between living alone or not and depressive symptoms in older adults: a parallel mediation effect of sleep quality and anxiety

The association of living alone and social isolation with sarcopenia: A systematic review and meta-analysis

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