Aiming to address the tracking accuracy and anti-rollover problem of the unmanned mining truck path tracking process under the complex unstructured road conditions in mining areas, a coordinated control strategy for path tracking and anti-rollover based on topology theory is proposed. Moreover, optimal equilibrium weights are assigned to path tracking control and anti-rollover control to ensure that the path tracking accuracy of the mining vehicle can be effectively improved in a safe and stable driving state. Regarding the path tracking problem, a lateral preview error model is established, and a path tracking controller is designed using LQR (linear quadratic regulator) control theory. In the design of the anti-rollover controller, the effects of understeer and trip-type rollover on the stability of the vehicle are taken into account, and the ideal transverse swing angular velocity and trip-type rollover evaluation index are introduced for controller design, which reduce the effects of the curves and roadway excitation on the mining truck and improve the rollover motion. Based on a joint simulation using Trucksim and Simulink and the construction of a hardware-in-the-loop simulation platform for verification, the single control strategy and coordinated control strategy are compared and analyzed. The final simulation results show that the tracking error, yaw velocity, and center of mass side deviation angle are optimized by 45%, 32.5%, and 20%, respectively. Therefore, the Extension theory-based coordinated controller satisfies the complex road conditions in the mining area and improves the tracking accuracy to the maximum extent while ensuring the safety and smoothness of vehicle driving and exhibiting good adaptability and robustness.