Small cell lung cancer: staging with MR imaging.

Abstract

Small cell lung cancer is an aggressive neoplasm; metastases are detected in two-thirds of patients at diagnosis with use of conventional staging, which includes bilateral bone marrow biopsy, bone scintigraphy, and computed tomography (CT) of the head and abdomen. In 25 patients, small cell lung cancer was staged prospectively with both conventional staging and a magnetic resonance (MR) imaging protocol that included 1.5-T MR imaging of the pelvis, abdomen, spine, and brain. According to conventional staging, 14 patients had extensive disease and 11 patients had limited disease; according to staging with MR, 19 patients had extensive disease and six had limited disease. All metastatic disease sites seen with conventional staging were identified on MR images. MR images showed additional metastatic involvement in bone (four patients) and liver (three patients) not detected at conventional staging. A low-attenuation hepatic lesion on a CT scan was identified as a hemangioma on MR images. These preliminary data suggest that small cell lung cancer may be accurately staged with use of a single MR imaging study.

Usefulness of magnetic resonance imaging for evaluation of cardiovascular invasion: Evaluation of sliding motion between thoracic mass and adjacent structures on cine MR images

“…Chest MRI may improve the detection of mediastinal disease and local invasion of an intrathoracic neoplasm by virtue of the short T1 value of fat, which is particularly useful in the case of allergies or renal insufficiency. The sensitivity and specificity of chest MRI are similar to those of the chest CT scan in identifying mediastinal and hilar metastases (14, 20). Despite the many merits of chest MRI, the utility of chest MRI is somewhat limited and less attractive for application to thoracic neoplasms because of its inability to produce images of the lung, its limited coverage due to longer image acquisition times, and its greater requirement for physician supervision compared to the chest CT scan for directing the imaging and maintaining examination quality (18, 19).…”

Role of positron emission tomography computed tomography in carcinoma lung evaluation

“…[55,56] SCLC is staged according to the Veterans Administration Lung Cancer Study Group recommendations, as limited disease (LD) or extended disease (ED). [57] LD is defined as tumor confined to the hemithorax and regional lymph nodes while ED includes tumor with non-contiguous metastasis to the contralateral lung and distant metastasis. [58] Most patients with SCLC have ED at presentation.…”

Kernspintomographie zum Metastasen-Screening? Ein prospektiver Vergleich mit der Skelettszintigraphie

“…In Übereinstimmung mit früheren Studien zur kernspintomographischen Erfassung von Sklettmetastasen (2,3,4,8,11,12,16,17,19,22) Die KST sollte derzeit nicht zum Screening nach ossären Metastasen angewandt werden, sondern eher als gezielte Zusatzuntersuchung bei fraglichen SkSz-Befunden. Eventuell werden zwar die neuen schnellen Bildgebungssequenzen (12) zukünftig eine kernspintomographische Ganzkörperuntersuchung erlauben, jedoch bleibt fraglich, ob die KST als Schnittbildverfahren Skelettbereiche wie Rippe und Schädel ähnlich sicher wie die 3-D-SPECT-Anwendung bei der SkSz darstellen kann.…”