Smart Nanogels for Biomedical Applications

Vashist, Arti; Kaushik, Ajeet; Chinnapaiyan, Srinivasan; Vashist, Atul; Nair, Madhavan

doi:10.1039/bk9781782626459-00267

Cited by 3 publications

(3 citation statements)

References 44 publications

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“…Pharmaceutical nanotechnology focuses on the development of therapeutically effective, biocompatible, and biodegradable nanoparticulate systems for enhanced drug bioavailability, targeted drug administration, and stability against chemical/enzymatic degradation [26]. Nanogels are regarded as a potential drug delivery system because of their beneficial features that combine those of hydrogels and nanoparticles.…”

Section: Advantages Of Biopolymer-based Nanogels Over Other Drug Deli...mentioning

confidence: 99%

Biopolymer-Based Nanogel Approach in Drug Delivery: Basic Concept and Current Developments

et al. 2023

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Due to their increased surface area, extent of swelling and active substance-loading capacity and flexibility, nanogels made from natural and synthetic polymers have gained significant interest in scientific and industrial areas. In particular, the customized design and implementation of nontoxic, biocompatible, and biodegradable micro/nano carriers makes their usage very feasible for a range of biomedical applications, including drug delivery, tissue engineering, and bioimaging. The design and application methodologies of nanogels are outlined in this review. Additionally, the most recent advancements in nanogel biomedical applications are discussed, with particular emphasis on applications for the delivery of drugs and biomolecules.

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Section: Advantages Of Biopolymer-based Nanogels Over Other Drug Deli...mentioning

confidence: 99%

Biopolymer-Based Nanogel Approach in Drug Delivery: Basic Concept and Current Developments

et al. 2023

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“…Nevertheless, the use of SMART materials within the biological field brings distinct obstacles and prospects. The increasing intricacy of healthcare needs necessitates the development of materials that possess the ability to adapt, respond, and seamlessly integrate into the complex biological systems of the human body [2]. This paper examines the progress and obstacles related to SMART materials in the field of biomedical applications within the given context.…”

Section: Introductionmentioning

confidence: 99%

SMART Materials for Biomedical Applications: Advancements and Challenges

Kumar,

Rajitha,

Rao

et al. 2023

E3S Web Conf.

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The advancement of SMART (Self-Healing, Multifunctional, Adaptive, Responsive, and Tunable) materials has had a significant impact on the domain of biomedical applications. These materials possess distinct characteristics that exhibit responsiveness to alterations in their surroundings, rendering them exceedingly appealing for a wide range of therapeutic applications. This study aims to examine the progress and obstacles related to SMART materials within the field of biomedicine. In recent decades, notable advancements have been achieved in the development, synthesis, and analysis of intelligent materials specifically designed for biomedical purposes. Self-healing materials have been employed in the development of implants, wound healing scaffolds, and drug delivery systems, drawing inspiration from natural regeneration mechanisms. The ongoing advancements in SMART materials have significant opportunities for transforming biological applications. The progression of nanotechnology, biomaterials, and bioengineering is expected to play a significant role in the advancement of materials that possess enhanced qualities and capabilities. The integration of SMART materials with emerging technologies such as 3D printing, gene editing, and microfluidics has the potential to create novel opportunities in the field of precision medicine and personalised healthcare. The effective translation of SMART materials from the laboratory to the clinic will need concerted efforts by researchers, physicians, regulatory agencies, and industry partners to address the present difficulties.

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“…This opened the possibility of gel interaction at the cellular level and the feasibility of systemic administration. Nanogels formation improved the stability and stimuli responsive characteristics, while restricting the swelling ability (Vashist et al, 2017;Verma et al, 2016).…”

Section: Introductionmentioning

confidence: 99%