Smart Portable Device Based on the Utilization of a 2D Disposable Paper Stochastic Sensor for Fast Ultrasensitive Screening of Food Samples for Bisphenols

Abstract

Since the determination of the high toxicity of bisphenol A, alternative structures for bisphenols have been synthesized, resulting in bisphenols C, E, F, S, and Z. These bisphenols have replaced bisphenol A in plastic bottles, toys, and cans used for preserving food. Later, the toxicity and negative effects of all of these bisphenols on people’s health were proven. Therefore, there is a need for a fast ultrasensitive screening method that is able to detect the presence of these bisphenols in any condition directly from food samples. This paper presented a disposable device based on the utilization of a 2D disposable paper stochastic sensor for the fast ultrasensitive screening of food samples for bisphenols A, C, E, F, S, and Z. The 2D disposable sensor was obtained by the deposition of graphene and silver nanolayers on paper using cold plasma. Furthermore, the active side of the sensor was modified using 2,3,7,8,12,13,17,18-octaethyl-21H,23H Mn porphyrin. The limits of quantification of these bisphenols were 1 fmol L−1 for bisphenols C and E, 10 fmol L−1 for bisphenols A and F, 10 pmol L−1 for bisphenol S, and 1 pmol L−1 for bisphenol Z. The recoveries of these bisphenols in milk, canned fruits, vegetables, and fish were higher than 99.00% with RSD (%) values lower than 1.50%.

Intelligent Miniplatform for On-Site Monitoring of Water Samples and Pharmaceutical Production of Ointments Based on Betamethasone and Gentamicin as Active Pharmaceutical Ingredients

“…A wide range of stochastic sensors has been proposed for the analysis of biomarkers, pharmaceuticals, foods, and water pollutants. [19][20][21][22][23][24][25] The enantiomers of a chiral molecule can be detected with the utilization of stochastic sensors. 26 Screen-printed electrodes (SPE) find extensive utility in electroanalysis due to their wide range of properties such as versatility for a wide array of molecules, reproducibility, ease and convenience in production and handling, flexible design, possibility for modification, and real-time, fast and reliable response.…”