Smartphone controlled interactive portable device for theranostics in vitro

Sailapu, Sunil Kumar; Dutta, Deepanjalee; Simon, Anitha T.; Ghosh, Siddhartha Sankar; Chattopadhyay, Arun

doi:10.1016/j.bios.2019.111745

Cited by 4 publications

(2 citation statements)

References 19 publications

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“…The device can be adapted for different radiation doses, and even can be used with a wireless operation in a smartphone application. [ 67 ] Au and Ag nanomaterials cannot be easily oxidized that are biologically inert in vivo. Besides, these nanomaterials present fascinating optical, chemical, and electrical properties in their nanoscale structures nanostructures, such as NPs, NRs, nanoshells, and nanostars.…”

Section: Multifunctional Inorganic Npsmentioning

confidence: 99%

All‐in‐One Nanomedicine: Multifunctional Single‐Component Nanoparticles for Cancer Theranostics

Cai

Chen

et al. 2021

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The development of cancer diagnostic imaging and treatment is a major concern worldwide. By integrating imaging and therapy into one theranostic nanoplatform for simultaneously detecting tumors, evaluating the targeting ability and timely monitoring therapeutic responses provide more opportunities for precision medicine. Among various theranostic nanosystems, a series of single‐component nanoparticles (NPs) have been developed for “all‐in‐one” theranostics, which presents the unique properties of facile preparation, simple composition, defined structure, high reproducibility, and excellent biocompatibility. Specifically, utilizing single‐component NPs for both diagnostics and therapeutics can reduce the possible numerous untoward side effects and risks to the living body. In this review, the recent progress of multifunctional single‐component NPs in the applications of cancer theranostics is systematically summarized. Notably, the structure design, categories of NPs, targeted strategies, biomedical applications, potential barriers, challenges, and prospects for the future clinical practice of this rapidly growing field are discussed.

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Section: Multifunctional Inorganic Npsmentioning

confidence: 99%

All‐in‐One Nanomedicine: Multifunctional Single‐Component Nanoparticles for Cancer Theranostics

Cai

Chen

et al. 2021

Small

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“…So far, many detection methods have been developed for the detection of the tau protein, including surface plasmon resonance (SPR) [ 7 , 8 ], surface-enhanced Raman spectroscopy (SERS) [ 9 ], field-effect transistors [ 10 , 11 ], colorimetry [ 12 ], fluorescence [ 13 , 14 ], and electrochemistry [ 15 , 16 , 17 ]. Among these methods, a portable electrochemical biosensor has tremendous potential for home health monitoring and personal healthcare due to its easy miniaturization, high sensitivity, and low cost [ 18 , 19 , 20 , 21 , 22 ]. A portable biosensor can be particularly significant as home health monitoring and personal healthcare become more and more common during the COVID-19 pandemic [ 23 , 24 ].…”

Section: Introductionmentioning

confidence: 99%

Portable Vertical Graphene@Au-Based Electrochemical Aptasensing Platform for Point-of-Care Testing of Tau Protein in the Blood

Liu

et al. 2022

Biosensors

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Alzheimer’s disease (AD) is a long-term neurodegenerative disease that poses a serious threat to human life and health. It is very important to develop a portable quantitative device for AD diagnosis and personal healthcare. Herein, we develop a portable electrochemical sensing platform for the point-of-care detection of AD biomarkers in the blood. Such a portable platform integrates nanoAu-modified vertical graphene (VG@Au) into a working electrode, which can significantly improve sensitivity and reduce detection limit due to the large specific surface, excellent electrical conductivity, high stability, and good biocompatibility. The tau protein, as an important factor in the course of AD, is selected as a key AD biomarker. The results show that the linear range of this sensing platform is 0.1 pg/mL to 1 ng/mL, with a detection limit of 0.034 pg/mL (S/N = 3), indicating that this portable sensing platform meets the demand for the detection of the tau protein in the blood. This work offers great potential for AD diagnosis and personal healthcare.

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An affordable automated LED array system for optimizing photodynamic therapy protocols

Larraga-Urdaz,

Vizcaíno,

Valledor

et al. 2023

Biosensors and Bioelectronics: X

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Smartphone controlled interactive portable device for theranostics in vitro

Cited by 4 publications

References 19 publications

All‐in‐One Nanomedicine: Multifunctional Single‐Component Nanoparticles for Cancer Theranostics

All‐in‐One Nanomedicine: Multifunctional Single‐Component Nanoparticles for Cancer Theranostics

Portable Vertical Graphene@Au-Based Electrochemical Aptasensing Platform for Point-of-Care Testing of Tau Protein in the Blood

An affordable automated LED array system for optimizing photodynamic therapy protocols

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