Smooth muscle-like cells in ovaries of the hamster and gerbil

McReynolds, Hal D.; Siraki, C.; Bramson, Paul H.; Pollock, Robert

doi:10.1007/bf00307055

Cited by 18 publications

(4 citation statements)

References 23 publications

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“…This study shows that some of the cells of the mouse ovary (mainly those located in the theca externa) have the cytological characteristics of SMC and confirms other ultrastructural observations on different mammalian species [Fumagalli and Motta, 1969;O 'Shea, 1970;Osvaldo-Decima, 1970;Fumagalli et al, 1971;Burden, 1973;Me Reynolds et al, 1973;Amenta et al, 1979;Pendergrass and Talbot, 1979].…”

Section: Discussionsupporting

confidence: 67%

Occurrence of a Contractile Tissue in the Theca externa of Atretic Follicles in the Mouse Ovary

Motta¹,

Familiari²

1981

Cells Tissues Organs

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In mature mouse ovaries, smooth muscle cells (SMC) are as a rule concentrated in the perifollicular stroma of developing follicles but are also present in different ovarian regions. In growing antral follicles SMC form a conspicuous investment (‘capsule’) of concentric layers of stretched and elongated elements located in the zones of the theca externa. On the contrary, in antral follicles reaching approximately the same growth phase but with clear signs of atresia, the contractile capsule of the follicles has an irregular outline due to an apparent dislocation and shortening of SMC. The ultrastructural findings show that in atretic follicles the majority of the cells forming this capsule possess the cytological characteristics of SMC fixed in contraction. The occurrence of compressed SMC in the wall of atretic follicles suggests that some relationship exists between follicle contraction and the atretic process. In the case of the follicle at ovulation, it may be suggested that the activation of such perifollicular contractile tissue, even if incapable of producing alone the dehiscence of the follicle, may nevertheless be capable of squeezing the follicular wall. Then, if other factors do not simultaneously occur to cause a normal ovulatory processs, the contraction of this tissue, instead of assisting in the rupture of the follicle, may favor its collapse and subsequent involution during atresia.

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Section: Discussionsupporting

confidence: 67%

Occurrence of a Contractile Tissue in the Theca externa of Atretic Follicles in the Mouse Ovary

Motta¹,

Familiari²

1981

Cells Tissues Organs

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“…There is an increasing amount of literature demonstrating the presence of smooth muscle or smooth muscle-like fibres in mammalian follicles (Burden, 1971(Burden, ,1973Fumagalli, Motta & Calvieri, 1971 ;McReynolds, Siraki, Branson & Polloch, 1973), but there is controversy whether such fibres are present in sufficient numbers and in the correct location to effect ovulation. While the thecal cells and microfilaments of Oryzias appear similar to the smooth muscle-like cells and fibres reported in the theca of the mammalian follicle (Osvaldo-Decima, 1970;O'Shea, 1971;Fumagalli et al, 1971;Burden, 1972Burden, , 1973Bjersing & Cajander, 1974), structures characteristic of smooth muscle, i.e.…”

Section: Discussionmentioning

confidence: 99%

The ultrastructure of the thecal cell of the teleost, Oryzias latipes, during ovulation in vitro

Pendergrass¹,

Schroeder²

1976

Reproduction

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Summary Ultrastructural examination of the follicular envelope of the teleost, Oryzias latipes, during ovulation in vitro showed that the follicle cell layer became increasingly dissociated. Microfilaments, measuring 50-70 \ l =A%o\ were sparse in the thecal cells at the start of incubation, but were organized into bands after 5 hr, and into bundles after 10 hr of incubation. It is suggested that these microfilaments are contractile and are involved in cell movement during ovulation.

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“…In some day-8 CL, a few SMC persist and may occur singly or in cords composed of several cells. Numerous studies have identified SMC in the ovarian stroma that are not associated with follicles, CL, or blood vessels (Osvaldo-Decima, 1970;McReynolds et al, 1973;Walles et al, 1978). They may be responsible for the spontaneous and drug induced contractions of the ovary that have been recorded by several researchers (Rocereto et al, 1969;Palti and Freund, 1972;Okamura et al, 1974;O'Shea and Phillips, 1974;Virutamasen et al, 1973).…”

Section: Discussionmentioning

confidence: 99%

“…In most mammals, excluding the hamster, the theca externa of preovulatory follicles is composed of spindle-shaped cells containing different amounts of cytoplasmic filaments (O'Shea, 1971(O'Shea, , 1973Burden, 1972;McReynolds et al, 1973). In the hamster, the apical theca externa is composed of fibroblasts whereas cells in the basal hemisphere display the characteristics of SMC (Gabella, 1973;Martin and Talbot, 1981a).…”

Section: Discussionmentioning

confidence: 99%

The fate of thecal smooth muscle cells in postovulatory hamster follicles

Martin¹,

Steenwyk²,

Miller‐Walker³

1983

Anat. Rec.

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Smooth muscles cells (SMC) have been identified in the theca externa of preovulatory follicles in several mammals. The function of these cells is not clear. It has been suggested that they are involved in ovulation and may play a role in the collapse of ruptured follicles and their transformation into corpora lutea (CL). In this study we used transmission electron microscopy (TEM) to examine the ultrastructure of SMC at the base of hamster follicles during the formation and regression of CL. For the first three days following ovulation, the CL are surrounded by a distinct theca externa composed of 1-3 layers of spindle-shaped cells. The cells were identified as SMC by the masses of filaments in the cytoplasm, dense attachment plaques and caveolae along the plasma membrane and an external lamina surrounding each cell. On the fourth day after ovulation, the theca externa is fragmented and TEM observations suggest the following three fates for theca externa cells: 1) many cells degenerate, 2) some cells persist as SMC, 3) some cells possess few or no filaments and appear similar to fibroblasts. The significance of these results is discussed in regard to ovarian contractions, the fate of CL, and the recycling of ovarian tissues.

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Smooth muscle-like cells in ovaries of the hamster and gerbil

Cited by 18 publications

References 23 publications

Occurrence of a Contractile Tissue in the Theca externa of Atretic Follicles in the Mouse Ovary

Occurrence of a Contractile Tissue in the Theca externa of Atretic Follicles in the Mouse Ovary

The ultrastructure of the thecal cell of the teleost, Oryzias latipes, during ovulation in vitro

The fate of thecal smooth muscle cells in postovulatory hamster follicles

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