Denote by P+(n) (resp. P−(n)) the largest (resp. the smallest) prime factor of the integer n. In this paper, we prove that there exists a positive proportion of integers n having no small prime factor such that P+(n)<P+(n+2). Especially, we prove that the pattern P+(P3)<P+(P3+2) is realized by a positive proportion of P3 with P−(P3)>x1/3−δ,0<δ≤112, where P3 denote an integer having at most three prime factors taken with multiplicity. We also prove that the pattern P+(p−1)<P+(p+1) holds for a positive proportion of primes under the Elliott-Halberstam conjecture.