Social and behavioral interventions for improving quality of life of HIV infected people receiving antiretroviral therapy: a systematic review and meta-analysis

Bhatta, Dharma Nand; Liabsuetrakul, Tippawan; McNeil, Edward

doi:10.1186/s12955-017-0662-4

Cited by 29 publications

(18 citation statements)

References 49 publications

(120 reference statements)

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“…Social and behavioral plans must be systematically integrated to potentially lower risk and consequently, disease transmission. However, there is a dearth in literature, specially with meta-analyses and comprehensive systematic reviews, regarding QoL of HIV infected patients receiving ART [13].…”

Section: Introductionmentioning

confidence: 99%

“…Additional factors include lower HIV viral load [19], higher CD4+ cell count [19–21] and less symptoms associated with HIV [22]. There is limited evidence on the impact of prevention plans and QoL, further meta-analyses and comprehensive systematic reviews focusing QoL among PWLHs’ who receive ART are lacking from the literature [13]. Therefore, the aim of this meta-analysis is to summarize the available clinical evidence reports (CD4 count, ART etc..) and its effects on QoL.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Clinical determinants associated with quality of life for people who live with HIV/AIDS: a Meta-analysis

Ghiasvand

Waye

Noroozi

et al. 2019

BMC Health Serv Res

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BackgroundDuring recent years, Quality of Life (QoL) is a significant assessment factor in clinical trials and epidemiological researches due to the advent of Antiretroviral Therapy (ART), Human Immunodeficiency Virus (HIV) has become a manageable,chronic disease. With regards, more attention must be paid to the QoL of infected patients. Limited evidence exists on the impact of ART on QoL among HIV infected patients. Due to lacking of a systematic approach to summarizing the available evidence on the clinical determinants of People Who Live with HIV/AIDS (PWLHs’) QoL, this study aimed to analyze the impact of clinical determinants (ART experience, CD4 count < 200, co-morbidities, time diagnosis and accessibility to cares) on QoL among PWLHs’.MethodsThis study was designed in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). PubMed, Science Direct, Web of Science, and Cochrane electronic databases were searched in February 2017 to identify all past studies that discussed social and behavioral characteristics of QoL in PLWHA. To recognize effective factors on social and behavioral QoL, a meta-analysis was conducted. Polled Odds Ratios (ORs) were utilized at a 95% confidence level. Since sampling methods differed between articles in the systematic review, we evaluated pooled estimates using a random effect model. Metan, metareg, metacum, and metabias commands in STATA version 13.0 were applied to analyze the data.ResultsOur findings indicated that ART has a positive impact on QoL, with a pooled effect size at approximately 1.04 with a confidence interval between 0.42 to 1.66 which indicates this impact is not very considerable and may be relatively neutral. The pooled effect size for CD4 count on QoL was .29 (95%CI = .22–.35), indicating that there is a negative associate between CD4 count and QoL. The co-morbidity as a negative determinant for QoL among HIV/AIDS infected people. The pooled effect size implies on a relative neutral association, although the confidence interval is wide and ranges between 0.32 to 1.58. The pooled effect size is about 1.82 with confidence interval 1.27 to 2.37 which indicates a considerable positive association with lowest level of heterogeneity.ConclusionsThe results illustrated that time diagnosing and availability to hospital services had significant relationship with a higher QoL and CD4 < 200 was associated with a lower QoL. In conclusion, policy makers should set an agenda setting to provide a suitable diagnostic and therapeutic facilities to early detecting and continues monitoring the health status of People Who Live with HIV/AIDS (PWLHs’).

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Clinical determinants associated with quality of life for people who live with HIV/AIDS: a Meta-analysis

Ghiasvand

Waye

Noroozi

et al. 2019

BMC Health Serv Res

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“…Improved health services for HIV/AIDS patients are needed to make sufferers healthier, more qualified and productive, so that they do not fall into the condition of AIDS and bring about many symptoms (14). Health services for people with HIV/AIDS must be provided early, especially when a patient's diagnosis is established (15). Patients will feel quality of life if the disease is at the stage of acceptance (16).…”

Section: Discussionmentioning

confidence: 99%

“…HIV sufferers can give each other support and work together. Some of the sufferers join the HIV/AIDS community and there are many events or activities to build their confidence and support each other (15,17,19).…”

Section: Discussionmentioning

confidence: 99%

Family Empowerment Model Based on Belief and Health-Related Quality of Life among Housewives With HIV/AIDS

Nursalam¹,

Efendi²,

Tristiana³

et al. 2020

SRP

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The trend of Human Immunodeficiency Virus/ Acquired Immunodeficiency Syndrome (HIV/AIDS) prevalence in Indonesia has increased significantly. This study was aimed to develop family empowerment model based on belief and analyze the effects of health-related quality of life (HRQL) in patients infected by HIV/AIDS. Mixed methods design with the first stage using quantitative research with cross sectional approach. A total 135 respondents with HIV/AIDS were determined from purposive sampling. For developing the model, we conducted focus group and expert discussion to make the model and the intervention tool for the second stage. We analyzed the collected data using Structural Equation Model Partial Least Squares (SEM-PLS) test. The outer loading value measured the sub-variable validity value of its latent variable, where the outer loading is valid if the value is >0.4. Based on the research results, nine indicators were invalid (outer loading value ≤ 0.4), and the indicator must be removed from the model. Evaluation of inner models was used to test the research hypotheses. The research hypothesis can be accepted if the value of T count >T table. The health services, patient factors, family factors and empowerment have a significant influence between some of these factors on HQRL (T >1.96). The development of a family empowerment model based on belief has a good effect in healthrelated quality of life among women with HIV/AIDS. From the developed model, it be seen that HRQL is related to health services, patient factors, family factors and empowerment.

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“…The better the personal system will affect health behavior and better quality of life. Bhatta et al (2017), stated that improving the quality of life in people living with HIV was influenced by healthy behaviors can affect PLWHA in the treatment or consume antiretroviral drugs that can improve the health of people living with HIV. Mental health care, healthy behaviors, and effective treatment can reduce risky sexual behavior and improve adherence to HIV care and treatment that can lead to reduced HIV transmission that can improve the quality of life of people living with HIV (Sikkema et al, 2010).…”

Section: The Effect Of Healthy Behaviour and Quality Of Lifementioning

confidence: 99%

The Effect of Depression, Stigma, and Peer Support Group, on the Quality of Life of People Living with HIV/AIDS in Solo Plus Peer Support Group, Surakarta, Central Java

Fajriyah

Demartoto

Murti

2018

J HEALTH PROMOT BEHAV

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Background: People Living with HIV/AIDS (PLWH) often face rough social problems, such as social rejection, stigma, and discrimination. Factors that affect PLWH's quality of life may include psychosocial factors, economic status, immunological status, social support, and co-morbidity. This study aimed to determine the effect of depression, stigma, and peer support group on the quality of life of people living with HIV/AIDS in Solo Plus peer support group, Surakarta, Central Java. Subjects and Method: This was an analytic observational study with a cross-sectional design. The study was conducted at Solo plus peer support group, Surakarta, Central Java, from January to February 2018. A sample of 100 PLWH was selected for this study by simple random sampling. The dependent variable was quality life of PLWH. The independent variables were healthy behavior, depression, family income, stigma, peer support, and social support. The data were collected by questionnaire and analyzed by path analysis. Results: Quality of life of PLWH increased with involvement in peer support group (b= 3.40; 95% CI= 0.71 to 6.10; p=0.001), social support (b= 0.70; 95% CI= 0.01 to 1.40; p=0.046), and healthy behavior (b=9.33; 95% CI= 5.30 to 13.36; p<0.001). Quality of life of PLWH decreased with stigma (b= -1.10; 95% CI=-1.84 to -0.36; p=0.003), and depression (b=-4.23; 95% CI=-6.62 to -1.83; p=0.001). Quality of life of PLWH was indirectly affected by income (b=0.06; 95% CI=10.14 to 18.61; p<0.001). Conclusion: Quality of life of PLWH is affected by healthy behavior, depression, stigma, peer support group, social support, and income.

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Social and behavioral interventions for improving quality of life of HIV infected people receiving antiretroviral therapy: a systematic review and meta-analysis

Cited by 29 publications

References 49 publications

Clinical determinants associated with quality of life for people who live with HIV/AIDS: a Meta-analysis

Clinical determinants associated with quality of life for people who live with HIV/AIDS: a Meta-analysis

Family Empowerment Model Based on Belief and Health-Related Quality of Life among Housewives With HIV/AIDS

The Effect of Depression, Stigma, and Peer Support Group, on the Quality of Life of People Living with HIV/AIDS in Solo Plus Peer Support Group, Surakarta, Central Java

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