Social participation in early and established rheumatoid arthritis patients

Benka, Jozef; Nagyová, Iveta; Rosenberger, Jaroslav; Macejová, Želmíra; Lazúrová, Ivica; Klink, Jac L. L. van der; Groothoff, Johan W.; Dijk, Jitse P. van

doi:10.3109/09638288.2015.1076071

Cited by 27 publications

(32 citation statements)

References 31 publications

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“…This is in line with two qualitative studies that highlighted personal empowerment and individual resources for overcoming disease-related restrictions. 35,36 …”

Section: Discussionmentioning

confidence: 99%

Quality of life in patients with established rheumatoid arthritis: A phenomenographic study

et al. 2017

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Objective:Patients with rheumatoid arthritis perceive reduced quality of life in several domains, such as physical health, level of independence, environment and personal beliefs, compared with the healthy population. There is an increasing interest in quality of life in clinical and medical interventions. Few studies have explored patients’ individual conceptions of quality of life, and interviews can thus complement quantitative studies. There is a need for a deeper understanding of the patients’ experiences of quality of life, with regard to living with a long-term condition such as rheumatoid arthritis. The aim of this study was to explore the variation of ways in which patients with established rheumatoid arthritis understand the concept of quality of life.Methods:The study had a qualitative design with a phenomenographic approach, which was used to describe variations in how individuals experience their quality of life. The study is based on interviews with 22 patients with established rheumatoid arthritis enrolled in the BARFOT (better anti-rheumatic pharmacotherapy) study.Results:The concept of quality of life could be understood in three different ways: (1) independence in terms of physical functioning and personal finances, (2) empowerment in how to manage life and (3) participation as an experience of belonging in a social context.Conclusion:The different conceptions of quality of life reflect the complexity in the concept, including physical, psychological and social aspects. This complexity is important to have in mind when health professionals support patients in enhancing their quality of life.

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“…This is in line with two qualitative studies that highlighted personal empowerment and individual resources for overcoming disease-related restrictions. 35,36 …”

Section: Discussionmentioning

confidence: 99%

Quality of life in patients with established rheumatoid arthritis: A phenomenographic study

et al. 2017

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“…Contemporary unmet needs in RA are changing; health domains of pain, fatigue and mood disturbance are closely linked and associated with restrictions in social participation. 10 , 11 In distinction to past generations of RA patients, where joint deformity and consequent disability were very evident to the treating physician, these contemporary unmet needs are of a subjective nature, and known only to the patient themselves. 11 However, key treatment goals of physicians are achieving remission, reduction in inflammation, prevention of structural damage and disability.…”

Section: The Burden Of Pain In Ramentioning

confidence: 99%

Pain in Rheumatoid Arthritis: Could JAK Inhibition be the Answer?

Mehta

Taylor

2020

MJR

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“…Можно с уверенностью утверждать, что РТДС и КН значительно усложняют ведение больных и ухудшают течение основного заболевания [10,11]. Сопутствующие РА ПР увеличивают риск развития коморбидных заболеваний, преждевременной летальности, способствуют прогрессированию связанных с РА функциональных ограничений, существенно затрудняют социальную адаптацию больных, негативно влияют на восприятие боли и выраженность ощущения усталости [10][11][12][13]. Что немаловажно, ПР также ассоциируются с низкой приверженностью больных РА лечению и являются ее предиктором [14].…”

Section: Factors Influencing the Efficiency Of Therapy In Patients Wiunclassified

Factors Influencing the Efficiency of Therapy in Patients With Rheumatoid Arthritis: The Role of Comorbid Mental and Somatic Diseases

Абрамкин¹,

Лисицына²,

Veltishchev³

et al. 2018

rsp

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The response rate to therapy for rheumatoid arthritis (RA) rarely exceeds 60%. Mental disorders (MDs) of the anxiety-depressive spectrum (ADS) and cognitive impairment (CI) substantially affect the evaluation of the efficiency of RA therapy. Adequate psychopharmacotherapy is one of the possible approaches to optimizing the treatment of RA. The factors influencing the efficiency of RA therapy with standard disease-modifying antirheumatic drugs (DMARDs) and biological agents (BAs) in combination with adequate psychopharmacotherapy have not been previously identified. Objective: to determine the predictors of response to therapy in patients with RA receiving DMARDs and BAs with or without adequate psychopharmacotherapy for ADS disorders. Subjects and methods. The investigation included 128 patients (13% men and 87% women) with a reliable diagnosis of RA. At baseline, 75.1% of patients received DMARDs; 7.8% – BAs. ADS disorders were detected in 123 (96.1%) patients. Psychopharmacotherapy was offered to all the patients with MDs; 52 patients agreed to treatment and 71 refused. The following therapeutic groups were identified according to the performed therapy: 1) DMARDs (n = 39); 2) DMARDs + psychopharmacotherapy (n = 43); 3) DMARDs + BAs (n = 32); 4) DMARDs + BAs + psychopharmacotherapy (n = 9). The changes of MDs symptoms and the outcomes of RA were assessed in 83 (67.5%) patients at five-year follow-up. The efficiency of RA therapy was evaluated with DAS28 (EULAR criteria). Predictors of response to therapy were determined using linear regression modeling. Results and discussion. At 5 years, 22 (26.5%) and 37 (44.6%) patients were recorded to show good and moderate responses to therapy, respectively; 24 (28.9%) patients were non-respondents. The linear regression model included 14 factors (p<0.001). The high values of DAS28 (β=0.258) at the inclusion; belonging to therapeutic groups 2 (β=0.267), 3 (β=0.235), and 4 (β=0.210), the absence of diabetes mellitus (β=-0.230), and experience in using glucocorticoids (β=-0.230) were associated with a high likelihood of response to therapy; high body mass index (β=-0.200) and long RA duration (β=-0,181), a high level of rheumatoid factor (β=-0.176), a history of myocardial infarction (β=-0.153), schizotypic disorder (β=-0.132), and extra-articular manifestations of RA (β=-0.106), and older age (β=-0.102) were related to a low probability of response. The area under the ROC curve for the model was 0.99 (p><0.001). Conclusion. BA therapy and psychopharmacotherapy, along with younger age, shorter duration and high activity of RA, a low level of rheumatoid factor, lower body mass index, the absence of diabetes mellitus, myocardial infarction, and extra-articular manifestations of RA in the history, schizotypic disorder, and experience in using glucocorticoids are associated with a greater likelihood of a good and moderate treatment response. Keywords: rheumatoid arthritis; mental disorders; disease-modifying antirheumatic drugs; biological agents; efficiency of therapy; predictors; psychopharmacotherapy; therapy adherence><0.001). The high values of DAS28 (β=0.258) at the inclusion; belonging to therapeutic groups 2 (β=0.267), 3 (β=0.235), and 4 (β=0.210), the absence of diabetes mellitus (β=-0.230), and experience in using glucocorticoids (β=-0.230) were associated with a high likelihood of response to therapy; high body mass index (β=-0.200) and long RA duration (β=-0,181), a high level of rheumatoid factor (β=-0.176), a history of myocardial infarction (β=-0.153), schizotypic disorder (β=-0.132), and extra-articular manifestations of RA (β=-0.106), and older age (β=-0.102) were related to a low probability of response. The area under the ROC curve for the model was 0.99 (p<0.001). Conclusion. BA therapy and psychopharmacotherapy, along with younger age, shorter duration and high activity of RA, a low level of rheumatoid factor, lower body mass index, the absence of diabetes mellitus, myocardial infarction, and extra-articular manifestations of RA in the history, schizotypic disorder, and experience in using glucocorticoids are associated with a greater likelihood of a good and moderate treatment response. Keywords: rheumatoid arthritis; mental disorders; disease-modifying antirheumatic drugs; biological agents; efficiency of therapy; predictors; psychopharmacotherapy; therapy adherence><0.001). Conclusion. BA therapy and psychopharmacotherapy, along with younger age, shorter duration and high activity of RA, a low level of rheumatoid factor, lower body mass index, the absence of diabetes mellitus, myocardial infarction, and extra-articular manifestations of RA in the history, schizotypic disorder, and experience in using glucocorticoids are associated with a greater likelihood of a good and moderate treatment response.

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Social participation in early and established rheumatoid arthritis patients

Cited by 27 publications

References 31 publications

Quality of life in patients with established rheumatoid arthritis: A phenomenographic study

Quality of life in patients with established rheumatoid arthritis: A phenomenographic study

Pain in Rheumatoid Arthritis: Could JAK Inhibition be the Answer?

Factors Influencing the Efficiency of Therapy in Patients With Rheumatoid Arthritis: The Role of Comorbid Mental and Somatic Diseases

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