Women play a role in the domestic sphere as housewives and also have a big role in the public sphere. Women become strategic actors in the community (public), especially in socio-economic development. The opportunity for women to take part in the public sphere, especially in the economic field to improve the social welfare of the family, still has an imbalance. This research is to answer the problem of how the demographic characteristics of socio-economic vulnerable women, forms of empowerment are given to socio-economic vulnerable women, how is the mobility of women to increase family income through productive economic enterprises, and the constraints and support faced by socio-economic vulnerable women in developing a productive economy to improve family welfare. The approach used is qualitative with a descriptive method. Subject targets were determined purposively, namely, women who were vulnerable to socio-economic issues and who had been empowered. The research locations were determined purposively in three provinces, namely Pekanbaru City, Riau Archipelago Province, West Bandung Regency, West Java Province, and Malang Regency, East Java Province. The results of the research can describe the empowerment and mobility of women from the domestic space to the public space to improve family welfare. Research innovations mainly lie in village and urban locations. In rural locations, it can be seen that the condition of women is weaker in terms of education, income, and involvement in the business world. In contrast to those in urban areas, the conditions of education, income, and the existence of corporate social responsibility involvement are the business world in urban areas.