Socioeconomic Predictors of Treatment Outcomes Among Adults With Major Depressive Disorder

Mills, Jeffrey A.; Suresh, Vikram; Chang, Lenisa V.; Mayes, Taryn L.; Croarkin, Paul E.; Trivedi, Madhukar H.

doi:10.1176/appi.ps.202100559

Cited by 11 publications

(2 citation statements)

References 15 publications

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“…The research's discovery of a concentration of Peruvian adults with depressive symptoms receiving treatment in the wealthiest quintiles reinforces this observation. The favorable socioeconomic conditions in these quintiles facilitate access to a diverse array of therapies-pharmacological, behavioral, and educationalwhich effectively tackle the challenges posed by the extended rehabilitation period and help prevent relapses in chronic conditions like depression (44)(45)(46). Also, low educational levels signi cantly impacted a reduced receipt of treatment for depressive symptoms (47,48).…”

Section: Discussionmentioning

confidence: 99%

Sociodemographic characteristics related to inequality in depression treatment in Peruvian adults: a concentration index decomposition approach

Intimayta-Escalante

2024

Preprint

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Background Depressive symptoms affect a significant proportion of Peruvian population, between 13.8% and 15.1% since 2014 to 2018. However, only the 14.1% did not receive treatment, this gap in treatment is influenced for sociodemographic conditions. The study aim was assessing demographic characteristics related to inequalities in the depression treatment receiving in Peruvian adults.Methods Utilizing data from the 2017–2022 Demographic and Health Survey, we conducted an analytic cross-sectional study. Inequality in treatment receipt was evaluated using concentration curves for estimated Concentration Index (CI), and the Erreygers Concentration Index (ECI), with the wealth index serving as an equity stratified. Decomposition analysis was employed to examine disparities among sociodemographic characteristics, including sex, age, education, residence, health insurance, and ethnicity.Results Of the 35,925 Peruvian adults with depressive symptoms surveyed, only 10.82% received treatment. Our analysis revealed treatment recipients were concentrated in higher wealth quintiles (CI: 22.08, 95% CI: 20.16 to 24.01, p < 0.01). Disparities persisted across various demographic groups, with urban residency (ECI: 0.03, 95% CI: 0.02 to 0.03, p < 0.001), those without education (ECI: 0.05, 95% CI: 0.03 to 0.07, p < 0.001), Afro-Peruvians (ECI: 0.06, 95% CI: 0.04 to 0.08, p < 0.001), and women (ECI: 0.07, 95% CI: 0.06 to 0.08, p < 0.001) experiencing lower received treatment, influenced by wealth quintile.Conclusion Only one in ten Peruvian adults with depressive symptoms received treatment. Sociodemographic conditions such as living in rural areas, outside of the capital region, having low educational level, and identifying as Quechua or Aymara were the main components of inequality in the receipt of treatment for depressive symptoms.

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Section: Discussionmentioning

confidence: 99%

Sociodemographic characteristics related to inequality in depression treatment in Peruvian adults: a concentration index decomposition approach

Intimayta-Escalante

2024

Preprint

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“… 31 However, even when receiving equal access to care, recent research has found poorer treatment outcomes for depression among more disadvantaged groups. 91 The differential exposure hypothesis posits that these observed social inequalities in health arise from variation in levels of exposure to stressors, and highlights that the efficacy of treating an individual in clinical practice may be limited until broader structural changes are meaningfully addressed through policy and public health. While ACEs are experienced by all creeds, they are not randomly distributed across the population.…”

Section: Discussionmentioning

confidence: 99%

An Umbrella Review of the Links Between Adverse Childhood Experiences and Substance Misuse: What, Why, and Where Do We Go from Here?

Grummitt¹,

Barrett²,

Kelly³

et al. 2022

SAR

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Background and Objectives A wealth of research has identified adverse childhood experiences (ACEs; abuse, neglect, violence or disorder in the home) as a strong risk factor for substance misuse. Synthesis of the existing evidence is critical to shape policy and inform directions for future research. Existing reviews have focused on specific substances or substance use outcomes (eg, disorder), and do not include discussion of the mechanisms that operate between ACEs and substance misuse. The current umbrella review aims to synthesize reviews on the relationship between ACEs and substance misuse, review the evidence on the mechanisms linking these, identify existing gaps in our knowledge, and discuss critical directions for future research, practice, and public policy. Methods Two electronic databases (PsycINFO and Medline) were searched for reviews published between 1998 and 2022 on the link between ACEs and substance misuse. Twenty articles met eligibility criteria and were qualitatively synthesized. Results Results overwhelmingly demonstrated an elevated risk of substance misuse or disorder, among adolescents and adults exposed to ACEs. Research on the mechanisms that explain this link highlights a multitude of potential intervention targets, with childhood stress propelling a cascade of effects across neurobiological, endocrine, immune, metabolic, and nervous systems, impacting psychosocial and cognitive functioning. Nonetheless, the literature is subject to limitations surrounding potential unmeasured cofounders and causality, as well as decontextualizing childhood adversity from broader structural issues that influence the link between ACEs and substance misuse. Research, policy, and practice that seek to holistically understand and address the relationship between ACEs and substance misuse within the broader social determinants of health is crucial.

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For Whom and for How Long Does the “Be a Mom” Intervention Work? A Secondary Analysis of Data From a Randomized Controlled Trial Exploring the Mid-Term Efficacy and Moderators of Treatment Response

Carona,

Pereira,

Araújo-Pedrosa

et al. 2024

Behavior Therapy

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Socioeconomic Predictors of Treatment Outcomes Among Adults With Major Depressive Disorder

Cited by 11 publications

References 15 publications

Sociodemographic characteristics related to inequality in depression treatment in Peruvian adults: a concentration index decomposition approach

Sociodemographic characteristics related to inequality in depression treatment in Peruvian adults: a concentration index decomposition approach

An Umbrella Review of the Links Between Adverse Childhood Experiences and Substance Misuse: What, Why, and Where Do We Go from Here?

For Whom and for How Long Does the “Be a Mom” Intervention Work? A Secondary Analysis of Data From a Randomized Controlled Trial Exploring the Mid-Term Efficacy and Moderators of Treatment Response

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