Sodium acetate/MWI: a green protocol for the synthesis of tetrahydrobenzo[α]xanthen-11-ones with biological screening

Mane, Prasad; Shinde, Bipin; Mundada, Pankaj S.; Gawade, V. B.; Karale, B. K.; Burungale, Arvind S.

doi:10.1007/s11164-019-03945-7

Cited by 15 publications

(1 citation statement)

References 36 publications

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“…12 Reaction of aldehydes with dimedone in the presence of various catalysts such as ionic liquids, silica sulfuric acid, resins, para dodecyl benzene sulfonic acid, sodium dodecyl sulfate, zinc oxide, acetyl chloride, zirconium, para toluene sulfonic acid, etc., has been reported for the synthesis of xanthenes. [13][14][15][16][17][18][19][20][21] However, some of these methods have long reaction times, harsh conditions and undesirable yields. So, optimization of the methods for the efficient synthesis of xanthenes has been widely demanded by chemists.…”

Section: Introductionmentioning

confidence: 99%

Accelerated synthesis of 1,8-dioxo-octahydroxanthene and 1,8-dioxo-decahydroacridine derivatives using dendritic mesoporous nanosilica functionalized by hexamethylenetetramine: a novel nanocatalyst

Sabri,

Shadjou,

Mahmoudian

2024

RSC Adv.

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Section: Introductionmentioning

confidence: 99%

Accelerated synthesis of 1,8-dioxo-octahydroxanthene and 1,8-dioxo-decahydroacridine derivatives using dendritic mesoporous nanosilica functionalized by hexamethylenetetramine: a novel nanocatalyst

Sabri,

Shadjou,

Mahmoudian

2024

RSC Adv.

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Recent Advances of Thiamine in Organic Synthesis

Zhang

2022

Adv Synth Catal

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Thiamine (VB1) has been proved to be a powerful biocatalyst for various organic transformations. VB1 offers several unique advantages, such as economical, non‐toxic, stable and water soluble. Excellent outcomes have been achieved in synthetic applications using VB1 as a catalyst. This review summarizes recent developments in the field of VB1 biocatalysis, allowing the construction of various biologically active heterocyclic scaffolds.

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New Bis(pyrazolo[5,1‐b]quinazolines) and Bis(9H‐xanthenediones) Linked to Alkane Cores: One‐Pot Synthesis, Antibacterial Screening, and SAR Study

Mekky,

Sanad

2024

Chemistry & Biodiversity

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Effective one‐pot methods were used to synthesize some new alkane‐linked bis(pyrazolo[5,1‐b]quinazolines) and bis(9H‐xanthenediones). The first series was produced, in 80‐88% yields, via the reaction of one equivalent of the appropriate bis(aldehydes) with two equivalents of 1H‐pyrazole‐3,5‐diamine and dimedone in DMF at 150 ºC for 5‐6 h. The second series was prepared, in 82‐89% yields, via the reaction one equivalent of the appropriate bis(aldehydes) with four equivalents of dimedone in acetic acid at 120 ºC for 4‐5 h. The new products displayed a broad range of antibacterial activity against different bacterial strains. Generally, the antibacterial activity of the alkane‐linked bis(pyrazolo[5,1‐b]quinazoline) units is more than 2‐fold their bis(9H‐xanthenedione) analogues. The (p‐tolylthio)methyl)‐linked bis(pyrazolo[5,1‐b]quinazolines) demonstrate the best antibacterial activity with MIC/MBC values up to 3.3/6.6 µM.

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Sodium acetate/MWI: a green protocol for the synthesis of tetrahydrobenzo[α]xanthen-11-ones with biological screening

Cited by 15 publications

References 36 publications

Accelerated synthesis of 1,8-dioxo-octahydroxanthene and 1,8-dioxo-decahydroacridine derivatives using dendritic mesoporous nanosilica functionalized by hexamethylenetetramine: a novel nanocatalyst

Accelerated synthesis of 1,8-dioxo-octahydroxanthene and 1,8-dioxo-decahydroacridine derivatives using dendritic mesoporous nanosilica functionalized by hexamethylenetetramine: a novel nanocatalyst

Recent Advances of Thiamine in Organic Synthesis

New Bis(pyrazolo[5,1‐b]quinazolines) and Bis(9H‐xanthenediones) Linked to Alkane Cores: One‐Pot Synthesis, Antibacterial Screening, and SAR Study

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