Sodium dodecyl sulfate reduces bacterial contamination in goat colostrum without negative effects on immune passive transfer in goat kids

Abstract

To investigate the use of sodium dodecyl sulfate (SDS) as a biocide on goat colostrum, 2 experiments were performed. In the first, 20 goat colostrum samples were divided into 3 aliquots. A different treatment was performed on each aliquot: pasteurization (56°C, 30 min) or addition of SDS to a final concentration of either 0.1 or 1% (36°C, 10 min). Immunoglobulin G and colony-forming units were evaluated before and after treatment. Both pasteurization and treatment with 1% SDS significantly reduced the colony-forming units in colostrum. Treatment with 0.1% SDS was not effective at reducing the colony-forming units in colostrum. The IgG concentration of pasteurized colostrum was significantly lower than that of untreated colostrum, whereas treatment with 1% SDS did not affect the colostrum IgG concentration. In the second experiment, the effects of SDS colostrum treatment on immune passive transfer were evaluated. Forty goat kids were fed either refrigerated colostrum or colostrum treated with 1% SDS twice daily for 2 d. Blood samples were obtained at birth and every day for 5 d. IgG, IgM, and IgA were measured in blood serum to monitor the passive immune transfer process. Creatinine, glucose, total cholesterol, blood urea nitrogen, bilirubin, and aspartate transaminase were also monitored to evaluate the health of kids. No differences in serum IgG, IgM, IgA, creatinine, glucose, total cholesterol, blood urea nitrogen, bilirubin, or aspartate transaminase levels were observed between groups. Our findings indicate that SDS is an efficient colostrum biocide that, unlike pasteurization, does not affect immune passive transfer or goat kid health.

The effect of colostrum source (goat vs. sheep) and timing of the first colostrum feeding (2 h vs. 14 h after birth) on body weight and immune status of artificially reared newborn lambs

“…The consumption of colostrum by the progeny of ruminant species (cow, sheep, and goat) has a fundamental role in passive immune transfer and in the survival rate of newborns (Lascelles, 1979;Stelwagen et al, 2009;Hernández-Castellano et al, 2014a), as they are born hypo-gammaglobulinemic. For this reason, animals growing under an artificial rearing system need to be fed, by bottle, an adequate amount of colostrum during their first days of life, to obtain adequate passive immune transfer and increase future productivity (Morales-delaNuez et al, 2011). Nevertheless, the amount of colostrum produced by the dam and its composition can be affected by several factors such as nutrition or litter size (Banchero et al, 2004).…”

Preliminary study of bovine colostrum quality in Latvia

“…Contaminated colostrum, however, may contain pathogens and can be an infectious disease transmitter, affecting morbidity and mortality rates of animals in the farms (Stewart et al, 2005;Morales-delaNuez et al, 2011;Mohammed et al, 2018). Bovine milk contains complex microbiota that affects quality and safety of the product.…”

Effect of bovine colostrum administration on plasma protein profile, growth, and survival in Red kid

“…This may be directly associated to the presence of various nutrients in colostrum. Besides providing energy and protein, the supplementation in colostrum probably helped bringing additional levels of vitamins (A and E) and minerals (zinc, selenium and iodine) which gave animals a way to develop and maintain a stronger immunity (Rawal et al, 2008;Morales-delaNuez et al, 2011). Colostrum is also rich in lactoferrin, which plays an important role in defending the body against pathogens (Ajello et al, 2002;Di Mario et al, 2003;Rawal et al, 2008).…”