1982
DOI: 10.1093/clinchem/28.3.449
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Sodium ion binding in human serum.

Abstract: The amount of sodium ion binding in human sera and in dialyzed human sera was estimated from standard-addition titrations with an ion-selective electrode and from measurements of 23Na nuclear magnetic resonance (NMR) linewidth. For the untreated sera, maximum binding was 1% (1.4 mmol/L) as indicated by NMR; virtually no binding was found via the titration method. For dialyzed sera with low-sodium, normal-protein content, NMR indicated that sodium binding was less than 1.3% (0.14 mmol/L). The same dialyzed flui… Show more

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Cited by 14 publications
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“…At the same time, much effort was made toward the integration of the resulting sensors into analytical systems, especially those intended for routine clinical analysis involving the rapid and, often, automated determination of electrolytes and dissolved gases in body fluid samples (1,3).…”
Section: Bioanalysis With Potentiometric Membrane Electrodesmentioning
confidence: 99%
“…At the same time, much effort was made toward the integration of the resulting sensors into analytical systems, especially those intended for routine clinical analysis involving the rapid and, often, automated determination of electrolytes and dissolved gases in body fluid samples (1,3).…”
Section: Bioanalysis With Potentiometric Membrane Electrodesmentioning
confidence: 99%