Sodium nitrite food poisoning in one family

Cvetković, Danica; Živković, Vladimir; Lukić, Vera; Nikolić, Slobodan

doi:10.1007/s12024-018-0036-1

Cited by 50 publications

(36 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Nevertheless, the lack of this sign in some cases can be attributed to a low concentration of methemoglobin at the time of death. 9 The classical chocolate colored-blood was slightly present in our case. Moreover, one of the most characteristic postmortem change was the blue-gray discoloration of the fingernail beds as signs of hypoxia due to methemoglobinemia.…”

Section: Discussionsupporting

confidence: 45%

“…In other studies, methemoglobinemia of 9.87% and 24.6 ng/mL of nitrites in the blood, 93.91 mg/kg in the stomach contents, and 0.003 mg/kg in the liver and kidney mixture were reported. 9 Blood nitrite levels in death cases following accidental or intentional ingestion were reported to be 0.55-13 μg/mL. 22,23 Methemoglobin concentrations were not analyzed in our case.…”

Section: Discussionmentioning

confidence: 73%

“…4 While non-lethal intoxications by contaminated water and food is widely reported, lethal cases are rarely described. [5][6][7][8][9] The estimated lethal dose of sodium nitrite in adults is approximately 2.6 g, 10,11 but survival was also reported for ingestion of 6 g sodium nitrite. 1 This work presents the first case described in the literature of a suicide by sodium nitrite after ordering a "suicide kit" on the internet.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A fatal case by a suicide kit containing sodium nitrite ordered on the internet

Durão

Pedrosa

Dinis-Oliveira

2020

Journal of Forensic and Legal Medicine

View full text Add to dashboard Cite

Fatal sodium nitrite poisonings are rare in the forensic context. The present work describes a first fatal case of sodium nitrite contained in a suicide kit that the victim acquired over the internet. The results of the autopsy showed general signs of asphyxia, such as intense cyanosis of the extremities, brown-gray-blue-red livor mortis, and some Tardieu petechiae in addition to intense visceral congestion. It is clear that forensic experts must be aware of the proliferation of this market and the risks of improper selling of these substances through suicide support networks available on the internet. The lack of knowledge of this reality may become unidentifiable, when toxicological analysis contemplates only the most classical and frequent substances involved in poisoning and reinforce the importance of a careful analysis of the death scene.

show abstract

Section: Discussionsupporting

confidence: 45%

Section: Discussionmentioning

confidence: 73%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A fatal case by a suicide kit containing sodium nitrite ordered on the internet

Durão

Pedrosa

Dinis-Oliveira

2020

Journal of Forensic and Legal Medicine

View full text Add to dashboard Cite

show abstract

“…As an oxidizer, nitrite can convert the ferrous iron (Fe 2+ ) of hemoglobin to ferric iron (Fe 3+ ), forming MetHb, and thereby impairing oxygen transport. Accumulating MetHb results in MetHb‐mia, which causes tissue or organ hypoxia that can lead to death . As the MetHb concentration increases, toxic symptoms will appear and it is generally lethal when the concentration exceeds 70%, although survival with a MetHb level of 94% has been reported .…”

Section: Discussionmentioning

confidence: 99%

“…Accumulating MetHb results in MetHb‐mia, which causes tissue or organ hypoxia that can lead to death . As the MetHb concentration increases, toxic symptoms will appear and it is generally lethal when the concentration exceeds 70%, although survival with a MetHb level of 94% has been reported . MN can induce MetHb‐mia, leading to symptoms including dizziness, nausea, palpitation, and cyanosis; furthermore, a victim has previously been reported to have “looked a bit blue” .…”

Section: Discussionmentioning

confidence: 99%

Fatal Methemoglobinemia Due to Acute Inhalation of Methyl Nitrite in an Industrial Accident

Huang

Wang²,

Guo³

et al. 2020

Journal of Forensic Sciences

View full text Add to dashboard Cite

Methyl nitrite is suggested to cause methemoglobinemia by generating methemoglobin, which may be lethal when the methemoglobin concentration exceeds 70%. However, intoxication with methyl nitrite is seldom reported compared with that with other nitrites. Here, we present an industrial accident involving methyl nitrite inhalation during its synthesis process that resulted in three fatalities and one survivor. The autopsy revealed conspicuous blue-gray discoloration in various parts of the body, including the skin, airway mucosa, vessels, brain, heart, and among other areas. The toxicological tests on the deceased showed methemoglobin concentrations in the blood over the lethal level and increased nitrite ion levels in the blood, gastric contents, liver, and lung tissue compared with those in control samples. The cause of death was determined to be methemoglobinemia-induced hypoxia due to methyl nitrite inhalation. This report provides evidence that in methyl nitrite intoxication, exposure duration has a significant influence on the postmortem changes and likelihood of a fatal outcome may be related to the age of the victim. More attention is required regarding the industrial hazards of this substance.

show abstract

Current perspective on veterinary drug and chemical residues in food of animal origin

Atta

Nasr

et al. 2022

Environ Sci Pollut Res

View full text Add to dashboard Cite

Sodium nitrite food poisoning in one family

Cited by 50 publications

References 8 publications

A fatal case by a suicide kit containing sodium nitrite ordered on the internet

A fatal case by a suicide kit containing sodium nitrite ordered on the internet

Fatal Methemoglobinemia Due to Acute Inhalation of Methyl Nitrite in an Industrial Accident

Current perspective on veterinary drug and chemical residues in food of animal origin

Contact Info

Product

Resources

About