Soft and dispersed interface-rich aqueous systems that promote and guide chemical reactions

Serrano-Luginbühl, Sandra; Ruiz-Mirazo, Kepa; Ostaszewski, Ryszard; Gallou, Fabrice; Walde, Peter

doi:10.1038/s41570-018-0042-6

Cited by 111 publications

(100 citation statements)

References 178 publications

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“…The tiny droplets of µEs have also been widely used as microreactors for the synthesis of organic and inorganic nanoparticles [ 4 , 102 , 103 ]. Inorganic nanoparticles have been customarily synthesized by w/o µEs.…”

Section: Achievements and Challengesmentioning

confidence: 99%

Microemulsion Microstructure(s): A Tutorial Review

et al. 2020

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Microemulsions are thermodynamically stable, transparent, isotropic single-phase mixtures of two immiscible liquids stabilized by surfactants (and possibly other compounds). The assortment of very different microstructures behind such a univocal macroscopic definition is presented together with the experimental approaches to their determination. This tutorial review includes a necessary overview of the microemulsion phase behavior including the effect of temperature and salinity and of the features of living polymerlike micelles and living networks. Once these key learning points have been acquired, the different theoretical models proposed to rationalize the microemulsion microstructures are reviewed. The focus is on the use of these models as a rationale for the formulation of microemulsions with suitable features. Finally, current achievements and challenges of the use of microemulsions are reviewed.

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Section: Achievements and Challengesmentioning

confidence: 99%

Microemulsion Microstructure(s): A Tutorial Review

et al. 2020

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“…65 Water as a solvent occupies a unique space here, and these subtle forces acting out on complicated potential energy surfaces on a multitude of time scales and distances, drive the final outcome of a chemical reaction. 66,67 For example, supramolecular chemistry is governed by a subtle interplay of non-covalent interactions between molecules, which gives rise to the formation of intricate self-organized chemical structures. 68 These processes were thought to be mostly driven by thermodynamics, but we now know that kinetics can be a determining factor, i.e., the selectivity and yield are dictated by the reaction pathway instead of the free energy of the product.…”

Section: Non-covalent Interactions and Photoionization Dynamicsmentioning

confidence: 99%

From atoms to aerosols: probing clusters and nanoparticles with synchrotron based mass spectrometry and X-ray spectroscopy

Ahmed

Kostko

2020

Phys. Chem. Chem. Phys.

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“…[32] Afterwards we verified, whether the reaction yield in the pH 5.2 can be improved by addition of a surfactant for transforming the homogeneous aqueous solution into a soft dispersed interface-rich aqueous system. [21] The experimental conditions were fixed at 0.1 M of each 1 a, 2 a, and 3 a, and 20 mol % surfactant with a reaction time of 24 hours at ambient temperature. The obtained yields of the product 4 a are given in Table 1.…”

Section: Resultsmentioning

confidence: 99%

“…[18] We have shown that the P-MCR can also proceed in water-surfactant solutions or dispersions, [19] In addition, surfactants were found as the promoters of various organic transformations. [20] Despite the fact of amphiphiles aptitude, [21] common surfactants are often produced from non-renewable feedstock. Also wastes obtained after reaction in the presence of fully synthetic surfactants can be problematic; for example according to the Sigma-Aldrich safety data sheet, DODAB waste should be dissolved or mixed with a combustible solvent and burned in a chemical incinerator equipped with an afterburner and scrubber.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Biodegradable Glucose Based Surfactants as a Promoting Medium for the Synthesis of Peptidomimetics with the Coumarin Scaffold

et al. 2020

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6‐O‐Glucose‐4‐phenylbutyrate was used successfully as promoting aqueous reaction medium for the synthesis of fourteen different α‐acyloxy carboxamides with the biologically relevant coumarin scaffold. Two different one‐pot protocols; chemical and chemoenzymatic, based on the usage of biodegradable surfactants for the synthesis of target products were developed. The chemoenzymatic method consists of 3‐steps in which the first step is oxidation catalyzed by Trametes versicolor laccase/O2, followed by spontaneous condensation reaction, and finally multicomponent Passerini reaction. All transformations occurred at room temperature in the same reaction vials without isolation of the reaction intermediates. The influence of the reaction conditions including substrate structure on the reaction course was studied. The application of an aqueous solution of 6‐O‐glucose 4‐phenylbutyrate as the reaction medium had the pivotal impact of the reaction rate providing target α‐acyloxy carboxamides with the yields up to 65 %. Obtained peptidomimetics were characterized by UV‐VIS and fluorescence spectroscopy.

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Soft and dispersed interface-rich aqueous systems that promote and guide chemical reactions

Cited by 111 publications

References 178 publications

Microemulsion Microstructure(s): A Tutorial Review

Microemulsion Microstructure(s): A Tutorial Review

From atoms to aerosols: probing clusters and nanoparticles with synchrotron based mass spectrometry and X-ray spectroscopy

Evaluation of Biodegradable Glucose Based Surfactants as a Promoting Medium for the Synthesis of Peptidomimetics with the Coumarin Scaffold

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