Soft dendritic microparticles with unusual adhesion and structuring properties

Roh, Sangchul; Williams, Austin; Bang, Rachel S.; Stoyanov, Simeon D.; Velev, Orlin D.

doi:10.1038/s41563-019-0508-z

Cited by 64 publications

(77 citation statements)

References 32 publications

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“…Formation of soft dendritic colloids from alginate. The alginate SDCs used as reinforcement networks were fabricated using a turbulent shear-driven precipitation process for the manufacturing of polymer dendricolloids 41 . In order to obtain hydrogel SDCs, a solution of alginate (120 -190 kDa) was injected in an aqueous solution of Ca 2+ ions, which effectively bind and crosslink two -COO-side groups on the alginate backbone (Fig.…”

Section: Fig1 | Turbulent Shear-driven Precipitation and Morphology mentioning

confidence: 99%

“…The hypothesis is that in aqueous suspensions, SDCs will adhere strongly to one another through van der Waals forces to form a percolating network of branched fiber sub-contacts ( Fig. 2a) 41 .…”

Section: Fig1 | Turbulent Shear-driven Precipitation and Morphology mentioning

confidence: 99%

“…The high degree of branching around the cores of the SDC particulates makes them morphologically similar to polymeric molecular dendrimers, but SDCs are orders of magnitude larger than these dendrimers 42,43 . Our previous studies with polymer SDCs dispersed in an organic oil medium showed that the branched, nanofibrous structure of the dendricolloids enables efficient network formation leading to gelation at low volume fraction due to enhanced van der Waals interactions 41,44 .…”

Section: Introductionmentioning

confidence: 99%

“…The hierarchically branched SDCs are expected to serve as efficient reinforcement in composite materials. Their branches provide large surface area, which could increase the composite stability by distributing the stress more uniformly 41,[45][46][47][48][49] . We investigate here the SDC effectiveness in reinforcing homocomposite hydrogels, expecting that the high surface area and maximized adhesivity between the SDC network and the matrix will result in hydrogels of outstanding mechanical properties.…”

Section: Introductionmentioning

confidence: 99%

“…These HHGs are reinforced by a fibrillar network of alginate soft dendritic colloids (SDCs). The SDCs are a hierarchically structured class of soft matter synthesized through a scalable process of shear-driven precipitation in a turbulent medium, described in our recent report 41 . The high degree of branching around the cores of the SDC particulates makes them morphologically similar to polymeric molecular dendrimers, but SDCs are orders of magnitude larger than these dendrimers 42,43 .…”

Section: Introductionmentioning

confidence: 99%

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Printable homocomposite hydrogels with synergistically reinforced molecular-colloidal networks

Williams

Roh

Jacob

et al. 2020

Preprint

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The design of hydrogels where multiple interpenetrating networks enable enhanced mechanical properties could benefit applications such as biomedical products, 3D printing, and soft robotics. We report a class of self-reinforced homocomposite hydrogels (HHGs) comprised of interpenetrating networks of multiscale hierarchy. A molecular alginate gel is reinforced by a colloidal network of hierarchically branched soft dendritic colloids (SDCs), which are also made of alginate. The reinforcement of the molecular gel with the nanofibrillar SDC network of the same biopolymer results in a remarkable increase of the HHG mechanical properties. The viscoelastic HHGs show >3× larger storage modulus and >4× larger Young's modulus than either constitutive network at the same concentration. Such synergistically enforced colloidal-molecular HHGs open numerous opportunities for formulation of biocompatible gels with robust structure-property relationships. Balance of the ratio of their precursors facilitates precise control of the yield stress and rate of self-reinforcement, enabling HHG 3D printing by extrusion.

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Section: Fig1 | Turbulent Shear-driven Precipitation and Morphology mentioning

confidence: 99%

Section: Fig1 | Turbulent Shear-driven Precipitation and Morphology mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Printable homocomposite hydrogels with synergistically reinforced molecular-colloidal networks

Williams

Roh

Jacob

et al. 2020

Preprint

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Engineering Natural Pollen Grains as Multifunctional 3D Printing Materials

Chen

Shi

Jang

et al. 2021

Adv Funct Materials

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The development of multifunctional 3D printing materials from sustainable natural resources is a high priority in additive manufacturing. Using an eco-friendly method to transform hard pollen grains into stimulus-responsive microgel particles, we engineered a pollen-derived microgel suspension that can serve as a functional reinforcement for composite hydrogel inks and as a supporting matrix for versatile freeform 3D printing systems. The pollen microgel particles enabled the printing of composite inks and improved the mechanical and physiological stabilities of alginate and hyaluronic acid hydrogel scaffolds for 3D cell culture applications. Moreover, the particles endowed the inks with stimulus-responsive controlled release properties. The suitability of the pollen microgel suspension as a supporting matrix for freeform 3D printing of alginate and silicone rubber inks was demonstrated and optimized by tuning the rheological properties of the microgel. Compared with other classes of natural materials, pollen grains have several compelling features, including natural abundance, renewability, affordability, processing ease, monodispersity, and tunable rheological features, which make them attractive candidates to engineer advanced materials for 3D printing applications.

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Evolution of Self‐Assembled Lignin Nanostructure into Dendritic Fiber in Aqueous Biphasic Photocurable Resin for DLP‐Printing

Wang,

Wu,

Wang

et al. 2024

Adv Funct Materials

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The design of lignin nanostructures where interfacial interactions enable enhanced entanglement of colloidal networks can broaden their applications in hydrogel‐based materials and light‐based 3D printing. Herein, an approach for fabricating surface‐active dendritic colloidal microparticles (DCMs) characterized by fibrous structures using nanostructured allylated lignin is proposed for the development of lignin‐based photocurable resins. With allyl‐terminated surface functionality of 0.61 mmol g−1, the entanglement between lignin‐DCM fibrils with a size of 1.4 µm successfully produces only lignin‐based hydrogels with structural integrity through photo‐crosslinking. The colloidal network of lignin dendricolloids reinforces the poly(ethylene glycol) (PEG) hydrogels during a digital light processing (DLP) 3D printing process by generating bicontinuous morphologies, resulting in six‐fold increases in toughness values with respect to the neat PEG hydrogel. The dual effectiveness of photoabsorption and free‐radical reactivity of lignin‐DCMs allow the light‐patterning of rather dilute PEG hydrogels (5–10%) with high geometric fidelity and structural complexity via DLP 3D printing. This study demonstrates a green and effective strategy for the design of 1D lignin‐DCMs that increases the versatility of the nanostructured biopolymer, opening up numerous opportunities for formulating functional hydrogels with robust structure‐property correlations.

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Soft dendritic microparticles with unusual adhesion and structuring properties

Cited by 64 publications

References 32 publications

Printable homocomposite hydrogels with synergistically reinforced molecular-colloidal networks

Printable homocomposite hydrogels with synergistically reinforced molecular-colloidal networks

Engineering Natural Pollen Grains as Multifunctional 3D Printing Materials

Evolution of Self‐Assembled Lignin Nanostructure into Dendritic Fiber in Aqueous Biphasic Photocurable Resin for DLP‐Printing

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