Soft tissue calcifications: a pictorial essay

Faria, Luisa Leitão de; Babler, Fernanda; Ferreira, Lorena Carneiro; Noronha, Ozeas Alves de; Marsolla, Felipe Lorenzo; Ferreira, Deusmaque Carneiro

doi:10.1590/0100-3984.2019.0100

Cited by 10 publications

(3 citation statements)

References 10 publications

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“…Other causes include disorders of calcium and phosphate metabolism, including hypoparathyroidism and PHP. Gout, which arises from hyperuricemia, is another potential cause of such calcifications [28]. Idiopathic calcifications can occur in tumoral calcinosis, a rare familial disease characterized by abnormal regulation of phosphate metabolism [29].…”

Section: Discussionmentioning

confidence: 99%

Cutaneous Calcified Mass of Foot in Pseudohypoparathyoidism: Case Report

Lee,

Kim,

Choi

et al. 2024

Medicina

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Soft tissue calcifications frequently appear on imaging studies, representing a prevalent but non-specific discovery, varying from a local reaction without clear cause to suggesting an underlying systemic condition. Because calcifications like these can arise from various causes, an accurate differential diagnosis is crucial. Differential diagnosis entails a methodical assessment of the patient, encompassing clinical presentation, medical history, radiological and pathological findings, and other pertinent factors. Through scrutiny of the patient’s medical and trauma history, we can refine potential causes of calcification to vascular, metabolic, autoimmune, neoplastic, or traumatic origins. Furthermore, routine laboratory assessments, including serum levels of calcium, phosphorus, ionized calcium, vitamin D metabolites, and parathyroid hormone (PTH), aid in identifying metabolic etiologies. We describe a rare occurrence of osteoma cutis in a 15-year-old female patient with a history of pseudohypoparathyroidism (PHP) and Albright’s hereditary osteodystrophy (AHO). The patient presented with a painful mass on the lateral side of her left foot. The diagnosis was based on medical history, laboratory tests, and imaging, leading to an excisional biopsy and complete pain relief post-surgery. Understanding such rare occurrences and related conditions is crucial for accurate diagnosis and management.

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Section: Discussionmentioning

confidence: 99%

Cutaneous Calcified Mass of Foot in Pseudohypoparathyoidism: Case Report

Lee,

Kim,

Choi

et al. 2024

Medicina

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“…It plays a vital role in several physiological events like muscle contraction, nerve conduction, haemostasis, bone formation 1 , etc. Soft tissue calcification is a common phenomenon affecting a wide range of tissues in the body; it could be of different varieties like dystrophic, iatrogenic, metastatic, or idiopathic 2 . Tissue calcification may involve various types of calcium salt depositions like calcium carbonate, calcium phosphate, hydroxyapatite, calcium apatite, calcium oxalate, etc.…”

Section: Introductionmentioning

confidence: 99%

Dystrophic Calcified Mass Found in the Semimembranosus Muscle in a Cadaver: A Case Report

2023

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Most of the soft tissue calcified mass formations are sporadic incidences that occur in an idiopathic form. Ectopic calcification changes were seen in various soft tissues beyond the skeleton. They are often asymptomatic masses located in the superficial or deeper aspect of the body, but may not be related to the bone directly. Increased levels of serum calcium, phosphate, or Vitamin D hypervitaminosis may be associated with the calcification process, causing mass accretion in the tissues like bones of limbs, and cranium, or showing some dental abnormalities. During the routine dissection of the hamstring compartment of the left lower limb in a male cadaver aged around 70 years in the Department of Anatomy, we noticed nodular fragments and lengthy slender pieces, which were hard in consistency and bony in its appearance found within the semimembranosus muscle. The histopathology of these masses was revealed as “Dystrophic Calcified Masses”. A holistic description of calcification changes in the soft tissues will be considered in the article. Keywords: calcification, dystrophy, hypervitaminosis

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“…Some STCs do not require any intervention or long-term surveillance, while others can be life-threatening with the underlying cause requiring treatment. Imaging methods such as MRI, CT, ultrasound, and even histological examination may be insufficient for the diagnosis of calcifications in some soft tissue-associated diseases [ 2 ]. Recently, the American College of Radiology (ACR) revised the criteria for imaging soft tissue masses.…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Radiographic Features of Head and Neck Soft Tissue Calcifications on Digital Panoramic Radiographs: A Retrospective Study

Acikgoz,

Akkemik

2023

Cureus

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Background In this study, we aimed to determine the prevalence and radiographic features of incidental head and neck soft tissue calcifications (STCs) on panoramic imagesand assess their clinical significance. Methodology Following well-established training and calibration procedures, 9,553 digital panoramic radiographs (DPRs) taken between January 1, 2021, and January 31, 22, were retrospectively evaluated. Only obvious calcifications and clear differential diagnoses were considered. The presence, type, side (i.e., unilateral or bilateral), number (single or multiple), and the presence of different calcifications in the same individual were recorded. STCs were recorded according to age and gender. Data were analyzed using the chi-square test and Fisher’s exact test using SPSS version 18.0 (IBM Corp., Armonk, NY, USA). Results Overall, 35.8% of the DPRs studied showed the presence of STCs, including ossified stylohyoid complex (OSHC) (10.3%), thyroid cartilage (9.8%), tonsillolith (9.2%), atherosclerotic plaques (5.8%), calcified triticeous cartilage (CTC) (5.1%), sialolith (1.9%), as well as intra-articular (1.3%) and other calcifications (0.1-0.8%), i.e., calcified lymph node, antrolith, rhinolith, phlebolith, and osteoma cutis. STCs were found to be more prevalent in middle-aged patients and in females. A significant relationship was identified between the presence of carotid artery calcification and calcified superior horn of thyroid cartilage (CSHTC), as well as between the presence of CSHTC and CTC. Calcifications were detected either bilaterally (n = 2,003) or unilaterally (n = 2,388); however, OSHC mostly showed bilateral calcifications (8.5%). Conclusions Panoramic radiographs of dental patients reveal the frequent occurrence of STCs in the head and neck region with differing radiographic features. Certain calcifications show gender and age differences. Accurate detection of STCs may guide the identification of potential underlying diseases and help initiate referral to the relevant multidisciplinary teams.

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Soft tissue calcifications: a pictorial essay

Cited by 10 publications

References 10 publications

Cutaneous Calcified Mass of Foot in Pseudohypoparathyoidism: Case Report

Cutaneous Calcified Mass of Foot in Pseudohypoparathyoidism: Case Report

Dystrophic Calcified Mass Found in the Semimembranosus Muscle in a Cadaver: A Case Report

Prevalence and Radiographic Features of Head and Neck Soft Tissue Calcifications on Digital Panoramic Radiographs: A Retrospective Study

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