Soft tissue tumors - Histopathological study of 93 cases

Hasan, Intisar S.; Suliman, Abdulkarem Y.; Hassawi, Bashar A.

doi:10.33899/mmed.2010.29083

Cited by 6 publications

(4 citation statements)

References 15 publications

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“…The mean age of patients with benign tumors was 41.72 years and that of malignant tumors was 51.11 years. On the contrary, in the study by Hassawi et al, 10 the mean age of patients with benign STT was 27.6 years, and in soft-tissue sarcomas, it was 39.1 years. In the present study, out of 152 cases, there were 81 males (53.29 %) and 71 females (46.71%).…”

Section: Discussionmentioning

confidence: 78%

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Histopathological study of soft-tissue tumors in a medical college in South India: A two-year study

Jyoti Brahmaiah,

Bharathi Sree,

Sai Prasad BV

et al. 2023

Asian J Med Sci

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Background: Soft tissue can be defined as non-epithelial extraskeletal tissue of the body exclusive of the reticuloendothelial system, glia, and supporting tissues of different parenchymal organs. These tumors are a highly heterogeneous group and are classified into benign, intermediate, and malignant forms according to the adult tissue they resemble. They can occur in all sites of the body. Aims and Objectives: The present study was undertaken to assess the histopathological pattern of various soft-tissue tumors. Materials and Methods: This is a prospective observational study for a period of 2 years, in which 152 soft-tissue tumors were analyzed and classified primarily as per the WHO classification. The age-wise, sex-wise, and site-wise distribution and the histopathological spectrum of soft-tissue tumors were studied. Results: A total of 152 soft-tissue tumors were included in the study, of which 90.79% were benign tumors, 5.92% were malignant, 2.63% were intermediate grade tumors, and 0.66% was of uncertain malignant potential. Maximum number of patients belonged to the 41–50-year age group. Males constitute 53.29% cases and females, 46.71% with a male-to-female ratio of 1.14:1. Lipoma was the most common soft-tissue tumor in the present study. Conclusion: Overall soft-tissue tumors are a rare category of tumors with benign tumors vastly outnumbering malignant tumors. The diagnosis of soft-tissue tumors needs a meticulous approach and team effort. Proper examination of the gross specimen and careful sampling of the tumor is required for the correct diagnosis. Hematoxylin- and Eosin-stained sections remain very important for the diagnosis of soft-tissue tumors along with immunohistochemistry and molecular markers.

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Section: Discussionmentioning

confidence: 78%

“…Malignant STT constituted 6.67% of all STT in their study. Another study on 93 soft-tissue tumors by Hassawi et al,10 for a period of 1 year (2007-2008) reported the incidence of benign and malignant soft-tissue tumors as 75.2% and 24.8%, respectively. Intermediate-grade tumors consisted of 2.63% of all soft-tissue tumors in the present study.…”

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confidence: 99%

Histopathological study of soft-tissue tumors in a medical college in South India: A two-year study

Jyoti Brahmaiah,

Bharathi Sree,

Sai Prasad BV

et al. 2023

Asian J Med Sci

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“…Abdominal wall endometriosis (AWE) and uterine fibroids (leiomyoma) affect the uterus and occur in females of childbearing age. While leiomyomas are smooth muscle tumors that grow from the uterine wall, AWE is a rare form of extra-pelvic endometriosis, Life 2023, 13, 1485 2 of 12 with the majority of cases occurring after cesarean section or abdominal surgery [3,4]. Desmoid tumors, also known as aggressive fibromatosis, are a rare type of benign STT that arise from fibrous tissue.…”

Section: Introductionmentioning

confidence: 99%

Transarterial Embolization and Percutaneous Ablation of Primary and Metastatic Soft Tissue Tumors

Shu

Lim

Fang

2023

Life

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Soft tissue tumors (STTs) include a range of benign and malignant tumors originating from soft tissues. Transarterial and percutaneous therapies are image-guided and minimally invasive approaches for managing primary and metastatic STTs. The objective of this review is to discuss transarterial and percutaneous therapies by examining the current literature, including indications, patient selection, safety, and effectiveness. Transarterial therapies (e.g., transarterial bland embolization and transarterial chemoembolization) involve the delivery of either embolic or chemotherapeutic particles using a catheter into arteries feeding the tumor, resulting in localized tumor destruction. Percutaneous therapies (e.g., radiofrequency ablation, cryoablation, irreversible electroporation, laser ablation, and magnetic resonance-guided high-intensity focused ultrasound) involve the delivery of either hot or cold temperatures, electrical current, laser, or ultrasound to specifically target tumor cells. Both therapies have been shown to be safe and effective for reducing morbidity and local control of STTs, specifically in patients who are surgically inoperable or who are unresponsive to conventional therapies. Accurate diagnosis, staging, and histological subtype identification are crucial for treatment selection. A multidisciplinary approach, a thorough understanding of tissue anatomy and surrounding structures, as well as individualized strategies based on assessment are essential for optimal patient care.

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“…When a soft tissue mass arises in a patient with no history of trauma or when a mass persisting even after 6 weeks after a local trauma a biopsy isindicated. They arise nearly everywhere in the body, the most important locations being the extremities, trunk, abdominal cavity and head & neck region [2] . It is sometimes possible to make an accurate diagnosis by detail clinical history, physical examination and naked eye examination of the tumors.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of benign and malignant soft tissue tumors presenting in a tertiary care hospital

Sharma,

Holla,

Chwla

et al. 2020

Int. J. Pathol. Sci.

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Soft tissue tumors are defined as mesenchymal proliferations that occur in extraskeletal, none pithelial tissue of the body, excluding the visceral organs. Both benign and malignant soft tissue tumors commonly present as a painless mass. A core biopsy, an excisional biopsy and an incisional biopsy are the appropriate technique used for diagnosing most soft tissue masses. This study was carried out to find out the proportion of different benign and malignant soft tissue tumors presenting in the hospital and to find the correlation between the clinical presentation and histopathological features of the soft tissue lesions. This observational study was conducted at a tertiary care hospital and patients from all age and sex groups were included. Detailed clinical data including history, findings of clinical examination and radiological findings were recorded. Site of soft tissue tumors has been categorised under head and neck, upper and lower extremities and trunk. In our study benign lesions comprise 89% and malignant 11% of total cases. The most common soft tissue tumor in our study is Lipoma followed by hemangioma, fibroma and schwannomas. Most common malignant soft tissue tumor in our study is high grade sarcoma with age predilection of 41-60 yrs age group.

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Soft tissue tumors - Histopathological study of 93 cases

Cited by 6 publications

References 15 publications

Histopathological study of soft-tissue tumors in a medical college in South India: A two-year study

Histopathological study of soft-tissue tumors in a medical college in South India: A two-year study

Transarterial Embolization and Percutaneous Ablation of Primary and Metastatic Soft Tissue Tumors

Prevalence of benign and malignant soft tissue tumors presenting in a tertiary care hospital

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