Aim. To highlight the peculiarities of transformational changes in land use in agrarian production in terms of soil fertility and farming effi ciency in Ukraine. To carry out a comparative analysis of the effi ciency of use of land resources in different European countries. To substantiate approaches to farming biologization in conditions of intensifi cation of agrarian production and climate change. Methods. Observation, comparison, analysis and synthesis, system analysis and forecast. Results. The results of long-term fundamental and applied researches on the effect of intensifi cation of agriculture on the productivity level of agrarian production have been analyzed. A benchmarking analysis of the effi ciency of use of land resources in Ukraine and European countries has been carried out. It has been established that as a result of economic activity the basic principle of interaction between the agriculture and livestock sector was violated, which does not allow to combine ef- fectively and use the
intensifi cation factors, the principle of fruit variability is not applied when introducing short crop rotations of the market crops. Conclusions. The effectiveness of agrarian production in conditions of transformational changes depends on the biological farming, which should be targeted at the rational use of land resources, prevention of degradation, preservation and enhancement of soil fertility and sustainable land use in time, use of life factors of agricultural plants taking into account their biological requirements.