Solid-phase immunofluorometric assay for quantification of CSF immunoglobulins

Takeoka, Tsuneyuki; Shinohara, Yukito; Mori, Kosuke; Furumi, Koichi

doi:10.1016/0022-510x(90)90135-a

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Intrathecal Synthesis Of Igm In Early Multiple Sclerosis1

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1991

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Cited by 3 publications

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“…We do not agree completely with this objection. In spite of the high hydrodynamic size of IgM, many studies showed a good correlation between the IgM level in the CSF and serum of normal subjects (4,5). We also had a good correlation between the CSF/plasma IgM ratio and the CSF/plasma albumin ratio in 57 tension headache subjects (r = 0.75, p < 0.01), suggesting that IgM physiologically penetrates the blood-brainbarrier in a way that can be compared with that of albumin (6).…”

Section: Intrathecal Synthesis Of Igm In Early Multiple Sclerosismentioning

confidence: 99%