Solid-pseudopapillary tumor of the pancreas: MR imaging findings in 21 patients

Guerrache, Youcef; Soyer, Philippe; Dohan, Anthony; Faraoun, S.A.; Laurent, V.; Tasu, Jean‐Pierre; Aubé, Christophe; Cazejust, J.; Boudiaf, Mourad; Hoeffel, Christine

doi:10.1016/j.clinimag.2014.01.015

Cited by 34 publications

(17 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Infiltrative growth pattern might cause the disruption of capsule and indicate the malignant behavior. Capsule morphology was significant between two groups ( P < 0.05), consistent with some studies [17, 18]. Notably, two patients who died of SPN had the incomplete capsule with infiltrative growth pattern.…”

Section: Discussionsupporting

confidence: 89%

Solid Pseudopapillary Neoplasm of the Pancreas: Clinicopathologic Feature, Risk Factors of Malignancy, and Survival Analysis of 53 Cases from a Single Center

Dong

Zhou

et al. 2017

BioMed Research International

View full text Add to dashboard Cite

Introduction Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare tumor of low malignant potential. The aim of this study was designed to evaluate the clinicopathologic feature, predictive factors of malignancy, and survival from experience of a single center. Methods 53 consecutive patients who underwent surgery for a pathologically definitive SPN were retrospectively reviewed. Results A total of 53 cases included 7 male cases and 46 female cases with the median age of 35.4 years (14–67). Abdominal pain and mass were the most common clinical presentations. The radiological presentations were consistent with solid and cystic pattern in 18 cases, solid pattern in 25 cases, and cystic pattern in 10 cases. The predominant location of tumor was pancreatic body and tail. The mean size of the tumors was 6.4 cm. Aggressive en bloc resection combined with organ-preserving should be indicated whenever feasible. Follow-up information was available for 48 patients with a median follow-up time of 48 months. The 5-year disease-specific survival was 95.7%. Incomplete capsule was not only the predictive factor of malignancy but also the significant predictor of disease-specific survival. Conclusion Incomplete capsule may suggest a malignant SPN and a prognostic indicator of disease-specific survival. We recommend that surgeons consider a more radical resection with an incomplete capsule of tumor.

show abstract

Section: Discussionsupporting

confidence: 89%

Solid Pseudopapillary Neoplasm of the Pancreas: Clinicopathologic Feature, Risk Factors of Malignancy, and Survival Analysis of 53 Cases from a Single Center

Dong

Zhou

et al. 2017

BioMed Research International

View full text Add to dashboard Cite

show abstract

“…Most patients have unclear clinical features including abdominal pain or discomfort, poor appetite and nausea, which are related to tumor compression on adjacent organs. Pain is the most pronounced complaint in these patients [1]. In our study, all patients had abdominal pain and abdominal discomfort while two patients had additional complaints of nausea/vomiting and one had palpable mass in the abdomen.…”

Section: Discussionmentioning

confidence: 45%

“…Solid Pseudopapillary Neoplasia (SPN) of the pancreas is a neoplasm with a low malignant potential, usually affecting young women in the second or third decade of life [1]. First reported by Frantz in 1959, it is an uncommon but distinct pancreatic neoplasm, constitutes only about 5% of cystic pancreatic tumors and about 1 to 2% of exocrine pancreatic neoplasms [2][3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of solid pseudopapillary tumor of the pancreas: one tertiary center experience

Kayar¹,

Ünver²,

Çoban³

et al. 2018

biomedicalresearch

View full text Add to dashboard Cite

Solid Pseudo-Papillary Neoplasia (SPN) is the rare tumors of the pancreas. The aim of the current study is documentation of the data of the patients. The data of patients with pancreatic neoplasm were presented to Gastroenterology Department between 2010 and 2014 were evaluated retrospectively. A database of the characteristics of these patients was developed, including demographic, laboratory, radiological, surgical and pathological features and the immuno-histochemical staining of tumor specimens. Analysis of 323 patients diagnosed with pancreas malignancies in our hospital between 2010 and 2014 demonstrated that 5 patients (1.5%) were diagnosed with SPN. Of these five patients, four were females and one was male. Their average age was 27 (range: 16-50). CA 19-9 levels were normal in four patients while slightly increase in one (60 U/mL (0-33)) and there were the other tumor markers under a normal range 5-10.3 cm diameter in size, mean: 7.6 cm. Immunohistochemical analysis demonstrated that CD10, CD56, Ki-67 and β-catenine was positive for all patients while other markers were variable. Progesteron and estrogen receptors were positive in histo-pathologic specimens of four patients. SPN is a rare tumor that develops principally in young women and has a good prognosis. Immunohistochemical staining is important in the differential diagnosis of SPN and estrogen positivity may have a role in pathogenesis of a limited patients.

show abstract

“…However, at present no reported study has definitely confirmed this assumption. (119). Solid pseudopapillary tumors have a lower ADC compared with normal parenchyma (2,38,64,101) with a mean ADC of 1.208 3 10 23 mm 2 / sec (range: 1.05 3 10 23 mm 2 /sec to 2.793 3 10 23 mm 2 /sec) at 1.5 T using b values of 0, 500 and 0, 400, 800 sec/mm 2 (2,64) and 0.98 3 10 23 mm 2 /sec 6 0.01 (range: 0.92 3 10 23 mm 2 /sec to 1.05 3 10 23 mm 2 /sec) at 3.0 T using b values of 0, 600 and 0, 100, 800 sec/mm 2 (Table 5) (38,101).…”

Section: Focal Pancreatic Diseasesmentioning

confidence: 99%

Diffusion-weighted MR Imaging of the Pancreas: Current Status and Recommendations

Barral¹,

Taouli²,

Guiu³

et al. 2015

Radiology

Self Cite

186

128

View full text Add to dashboard Cite

Advances in image quality over the past few years, mainly due to refinements in hardware and coil systems, have made diffusion-weighted ( DW diffusion weighted ) magnetic resonance (MR) imaging a promising technique for the detection and characterization of pancreatic conditions. DW diffusion weighted MR imaging can be routinely implemented in clinical protocols, as it can be performed relatively quickly, does not require administration of gadolinium-based contrast agents, and enables qualitative and quantitative assessment of tissue diffusivity (diffusion coefficients). In this review, acquisition parameters, postprocessing, and quantification methods applied to pancreatic DW diffusion weighted MR imaging will be discussed. The current common clinical uses of DW diffusion weighted MR imaging (ie, pancreatic lesion detection and characterization) and the less-common applications of DW diffusion weighted MR imaging used for the diagnosis of pancreatic parenchymal diseases will be reviewed. Also, the limitations of the technique, mainly image quality and reproducibility of diffusion parameters, as well as future directions for pancreatic DW diffusion weighted MR imaging will be discussed. The utility of apparent diffusion coefficient ( ADC apparent diffusion coefficient ) measurement for the characterization of pancreatic lesions is now well accepted but there are a number of limitations. Future well-designed, multicenter studies are needed to better determine the most appropriate use of ADC apparent diffusion coefficient in the area of pancreatic disease.

show abstract

Solid-pseudopapillary tumor of the pancreas: MR imaging findings in 21 patients

Cited by 34 publications

References 35 publications

Solid Pseudopapillary Neoplasm of the Pancreas: Clinicopathologic Feature, Risk Factors of Malignancy, and Survival Analysis of 53 Cases from a Single Center

Solid Pseudopapillary Neoplasm of the Pancreas: Clinicopathologic Feature, Risk Factors of Malignancy, and Survival Analysis of 53 Cases from a Single Center

Evaluation of solid pseudopapillary tumor of the pancreas: one tertiary center experience

Diffusion-weighted MR Imaging of the Pancreas: Current Status and Recommendations

Contact Info

Product

Resources

About