Solid State Reactions of Hemin with Basic Substances: Formation of bis and Mixed Complexes

Paneque, Armando; Bertrán, José Fernández; Reguera, E.; Yee‐Madeira, H.

doi:10.1023/b:stuc.0000007566.08376.02

Cited by 5 publications

(6 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To understand the mutual coordination of hemin, OBBA, and Tb 3+ , we measured the FT-IR spectrum of Tb-OBBA-Hemin. As shown in Figure b, the peaks at 1703 cm –1 , which is assigned to the stretching vibration of CO of hemin, and the peak at 1685 cm –1 , which is attributed to the stretching vibration of CO of OBBA disappeared in the IR spectrum of Tb-OBBA-Hemin. , Meanwhile, the asymmetric and symmetric vibration peaks of C–O of OBBA shifted from 1690 and 1501 cm –1 to 1599 and 1541 cm –1 , respectively . These changes suggest that hemin and OBBA might combine with Tb 3+ ion through their respective carboxyl groups.…”

Section: Resultsmentioning

confidence: 89%

“…36,37 Meanwhile, the asymmetric and symmetric vibration peaks of C−O of OBBA shifted from 1690 and 1501 cm −1 to 1599 and 1541 cm −1 , respectively. 38 These changes suggest that hemin and OBBA might combine with Tb 3+ ion through their respective carboxyl groups. In addition, a new broad peak around 3400 cm −1 appeared in the spectrum of Tb-OBBA-Hemin, implying the presence of uncoordinated COOH group and hydrogen-bonded COOH group of Tb-OBBA-Hemin.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Luminescence-Sensing Tb-MOF Nanozyme for the Detection and Degradation of Estrogen Endocrine Disruptors

Wang

Chen

2020

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

Using flexible structures and components of metal-organic framework (MOF) materials, we designed and developed an artificial nanozyme with dual functions of a catalyst and luminescent sensor specifically for the determination and degradation of hormone 17β-estradiol (E2) and its derivatives (E1, E3, and EE2), a class of disruptors with strong effect on the human endocrine system. This nanozyme composed of the luminescent Tb3+ ion, catalytic coenzyme factor hemin, and light-harvesting ligand can be used to both degrade E2 like natural horseradish peroxidase (HRP) and sense E2 as low as 50 pM by its luminescence. The nanozyme catalyzes the decomposition of E2 and its derivatives through a mechanism of active hydroxyl radicals and oxidative high-valent iron-oxo intermediates. The prepared nanozyme is pluripotent, stable, and cheap and can replace the widely used combination of natural enzyme and chromogenic substrate. The present strategy of constructing artificial enzymes directly from functional units provides a new way for the design and development of smart, multifunctional artificial enzymes.

show abstract

Section: Resultsmentioning

confidence: 89%

Section: Resultsmentioning

confidence: 99%

Luminescence-Sensing Tb-MOF Nanozyme for the Detection and Degradation of Estrogen Endocrine Disruptors

Wang

Chen

2020

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

show abstract

“…The FTIR spectrum in the fingerprint region of hemin showed the side-chain carboxy ethyl, vinyl, and methyl groups of the protoporphyrin ring (Figure B, curve a) . The sharp band at 1706 cm –1 corresponded to the CO stretch of the carboxylic acid groups .…”

Section: Resultsmentioning

confidence: 99%

Electrochemiluminescent Quenching of Quantum Dots for Ultrasensitive Immunoassay through Oxygen Reduction Catalyzed by Nitrogen-Doped Graphene-Supported Hemin

et al. 2013

View full text Add to dashboard Cite

A hemin functionalized graphene sheet was prepared via the noncovalent assembly of hemin on nitrogen-doped graphene. The graphene sheet could act as an oxygen reduction catalyst to produce sensitive electrochemiluminescent (ECL) quenching of quantum dots (QDs) due to the annihilation of dissolved oxygen, the ECL coreactant, by its electrocatalytic reduction. With the use of the catalyst with high loading of hemin as a signal tag of the secondary antibody, a novel ultrasensitive immunoassay method for biomarker detection was proposed. In an air-saturated pH 8.0 buffer, the immunosensor constructed by a stepwise immobilization of bidentate-chelated CdTe QDs and capture antibody showed an intensive cathodic ECL irradiation, which could be scavenged upon the formation of the catalyst-bound sandwich immunocomplex. With the use of the carcinoembryonic antigen as a model analyte, the immunoassay method showed a linear range from 0.1 pg mL(-1) to 10 ng mL(-1) and a detection limit of 24 fg mL(-1). The immunosensor exhibited good stability, acceptable fabrication reproducibility, and practicability. The electrocatalytic reduction-based ECL quenching strategy provided a powerful avenue for the design of the ultrasensitive detection method, showing great promise for clinical application.

show abstract

“…Besides the peripheral -COOH groups, the axial positions of the central iron atom give hemin another possible reaction site. 31 Since the presence of the N1s (Fig. 5) and Fe-2p core-level lines (Fig.…”

Section: Xpsmentioning

confidence: 96%

Hemin interaction with bare and 4,4′-thio-bis-benzene-thiolate covered n-GaAs (110) electrodes

Preda

Negrilǎ

Lazarescu

et al. 2011

Phys. Chem. Chem. Phys.

View full text Add to dashboard Cite

Cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) investigations on the redox behavior of hemin at bare and 4,4'-thio-bis-benzene-thiolate (TBBT) covered n-GaAs (110) electrodes in dimethylsulfoxide (DMSO) revealed the high irreversibility of the electroreduction process, which appeared to be closely related to the stable adsorbed species strongly interfering with the electronic properties of the semiconducting substrate. The subsequent exploration of the hemin-modified electrodes by second harmonic generation (SHG), X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM) measurements pointed to significant differences between the iron protoporphyrin species adsorbed on the bare- and TBBT-GaAs (110) electrodes. Only Fe(2+) species having a flat configuration with the porphyrin plane oriented parallel to the surface were detected on GaAs, unlike the TBBT-GaAs, where Fe(2+) and Fe(3+) species having both flat and vertical adsorption positions could be observed. These differences originate from the mutual interactions between the solvent, hemin and dithiolate molecules as well as their competition for the surface sites found to play a key role in the electrochemical process under discussion.

show abstract

Solid State Reactions of Hemin with Basic Substances: Formation of bis and Mixed Complexes

Cited by 5 publications

References 12 publications

Luminescence-Sensing Tb-MOF Nanozyme for the Detection and Degradation of Estrogen Endocrine Disruptors

Luminescence-Sensing Tb-MOF Nanozyme for the Detection and Degradation of Estrogen Endocrine Disruptors

Electrochemiluminescent Quenching of Quantum Dots for Ultrasensitive Immunoassay through Oxygen Reduction Catalyzed by Nitrogen-Doped Graphene-Supported Hemin

Hemin interaction with bare and 4,4′-thio-bis-benzene-thiolate covered n-GaAs (110) electrodes

Contact Info

Product

Resources

About