Semiconducting poly(3-aminophenylboronic acid) (PABA) and poly(thiophene-3-boronic acid) (PTBA) nanoparticles are synthesized using KIO 3 and (NH4) 2 S 2 O 8 as initiators, respectively; and structural, morphological, and surface characterizations are carried out by various well-known techniques. Electrokinetic properties of PABA and PTBA dispersions are determined by zeta ( ζ )-potential measurements in aqueous medium by taking the effects of pH, various electrolytes, surfactants, and temperature into account. Colloidally stable range of +30 mV ≤ ζ ≤ −30 mV is obtained in the presence of NaCl and Na 2 SO 4 for PABA and PTBA, respectively. Addition of anionic surfactant, sodium dodecyl sulfate, to PABA and PTBA dispersions shifts the ζ -potentials to more negative values and enhances their colloidal stabilities. ζ -Potential values of PABA increase with rising temperature, whereas almost no change is observed for PTBA at elevated temperatures up to 65 °C. ζ -Potentials of PABA and PTBA dispersions in silicone oil with the absence and presence of Triton X-100 are also determined to be high. nanostructured organoboron conducting polymers have been attracted by many scientists due to their extraordinary properties which are very different from the bulk. [ 3 ] In the last decades, organoboron polymers attracted many researchers as a new class of materials since introduction of boron atom to π-conjugated systems provides supreme properties such as electrical conductivity, anion sensing ability, third-order nonlinear optical property, and fl uorescence emission. [ 4 ] So, this new class of polymers has potential applications for environmental protections, displays, and biomedical applications. [ 5,6 ] Among the organoborons, boronic acids possessing trivalent boron atoms bonded to alkyl/aryl and two hydroxyl groups are most preferable since they are thermally stable, inert against water and oxygen, also water soluble, and have low toxicity. [ 7 ] Furthermore, since their ability to reversibly form covalent complexes with 1,2 and 1,3 diols, boronic acid containing polymers have been extensively investigated for biomedical applications such as RNA isolation, [ 8 ] sugar sensing systems, [ 9 ] glycopeptide enrichments, [ 10 ] and hemoglobin detections. [ 11 ]