Solitary Extramedullary Plasmacytoma of the Thyroid Gland

Ridal, M.; Ouattassi, Naouar; Harmouch, T.; Amarti, Afaf; Alami, M. N. El

doi:10.1155/2012/282784

Cited by 11 publications

(13 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Lymphocytic thyroiditis is usually accompanies EMP of thyroid gland [4] however, some studies have not found any association between lymphocytic thyroiditis and EMP. [10] In our case; we did not find any histological features of underlying lymphocytic thyroiditis. Common histological mimickers of EMP thyroid include medullary carcinoma of thyroid [11] and lymphoplasmacytic lymphoma.…”

Section: Discussioncontrasting

confidence: 42%

Primary Plasmacytoma of Thyroid Gland—an Interesting Case Diagnosed By FNAC

Bhattacharjee¹,

Mondal²,

Dey³

et al. 2017

OGH Reports

View full text Add to dashboard Cite

Introduction: Primary plasmacytoma of the thyroid gland is a rare disease. Extramedullary plasmacytoma (EMP) comprises 3-5% of all plasma cell neoplasm. Case report: A 57-yearsold female presented with a large thyroid swelling involving the left lobe and isthmus, firm in consistency and moved a little with deglutition. CT scan revealed a large solid tumor (9.5 cm in greatest dimension) affecting thyroid gland. CT scan report gave differential diagnoses of plasmacytoma and metastatic carcinoma. FNAC revealed hypercellular smears composed of plasma cells with eccentrically placed nuclei and perinuclear hoff. Hematological work up and other relevant investigations including urine for Bence Jones protein ruled out multiple myeloma or other plasma cell dyscrasias. Subsequent histopathological examination and IHC (immunohistochemistry) confirmed the diagnosis of primary plasmacytoma of thyroid. Discussion: EMP can present with elevated anti thyroid antibodies and can be associated with lymphocytic thyroiditis; however, in our patient these findings were not present.

show abstract

Section: Discussioncontrasting

confidence: 42%

Primary Plasmacytoma of Thyroid Gland—an Interesting Case Diagnosed By FNAC

Bhattacharjee¹,

Mondal²,

Dey³

et al. 2017

OGH Reports

View full text Add to dashboard Cite

show abstract

“…Similarly Ridal et al . [ 9 ] diagnosed a case of EMP as lymphoplasmacytic lymphoma on cytology. Sarin et al .…”

Section: Discussionmentioning

confidence: 99%

Extramedullary plasmacytoma of thyroid - a mimicker of medullary carcinoma at fine needle aspiration cytology: A case report

Bhat

Shariff

Reddy

2014

J Cytol

View full text Add to dashboard Cite

A rare case of extra medullary plasmacytoma (EMP) of thyroid gland in a 60 year old male, occurring against a background of Hashimoto's thyroiditis is reported. The fine needle aspiration cytology (FNAC) initially done as an outpatient procedure, showed atypical epithelial cells on a background of amyloid. Considering these findings we gave a diagnosis of medullary carcinoma. Histology of the total thyroidectomy specimen showed an extensive infiltration of neoplastic plasma cells against a background of Hashimoto's thyroiditis, with a bizarre Hurthle cell change. Immunohistochemistry on the histology sections confirmed the diagnosis of solitary plasmacytoma of thyroid against a background of Hashimoto's thyroiditis.

show abstract

“…The treatment of EMP remains controversial; all three modalities, including radiotherapy alone, surgery alone, or a combined approach, are advocated by various authors [ 11 ]. Although EMP is very sensitive to radiotherapy and complete remission can be achieved by irradiation alone in most cases, surgery remains the treatment of choice if the tumor is resectable.…”

Section: Discussionmentioning

confidence: 99%

“…The patient has been followed up regularly in the surgical OPD for the last eight months and has remained asymptomatic to date. Long-term follow-up of EMP is advised, as around 20% cases of EMP may progress to MM [ 11 ].…”

Section: Discussionmentioning

confidence: 99%