Solitary fibrous tumor located in the sella turcica: A report of two cases and review of the literature

Xiao, Yang; Jiang, Qingjun; Yu, Bin

doi:10.3892/ol.2015.3162

Cited by 11 publications

(14 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 17 Still, CT and MRI features of SFTs are nonspecific, revealing well-defined and often lobulated soft tissue space-occupying masses that displace adjacent anatomic structures. 18 , 19 For our 20 cases, 12/20 patients with SFTs who were diagnosed in our single hospital were located in extrapleural sites (60%). SFTs of different sizes had different features according to CT and MRI.…”

Section: Discussionmentioning

confidence: 96%

Variable Solitary Fibrous Tumor Locations

et al. 2016

View full text Add to dashboard Cite

The aim of the study is to describe the radiological imaging features of different solitary fibrous tumors (SFTs) locations and present histopathological correlations.From 2007 to 2013, 20 cases of histologically confirmed that SFTs were retrospectively analyzed with computed tomography (CT; 9/20), magnetic resonance imaging (MRI; 5/20), or both CT and MRI (6/20).All 20 SFTs were well defined, lobular, soft-tissue masses, and 60% were located outside of the pleura. One pleural case invaded to the 10th thoracic vertebra and had lung metastases. Images revealed 11 heterogeneous lesions that exceeded 3.0 ± 0.203 cm along the greatest axis with patchy necrotic foci, and 9 homogeneous lesions <3.0 ± 0.203. Microscopically, all SFTs were proliferative spindle cells with varying degrees of fibrosis and interspersed vessel branching. Cells were strongly immunopositive for CD34.Here we review variable imaging findings of SFTs, which can be within the pleura as well as within other serosal tissues such as the meninges and postperitoneum. SFTs > 3.0 ± 0.203 cm along the greatest axis appeared to be mixed patterns, whereas SFTs < 3.0 ± 0.203 cm had isodense appearances. SFTs cells were CD34 immunopositive and surgery was a first-line treatment choice.

show abstract

Section: Discussionmentioning

confidence: 96%

Variable Solitary Fibrous Tumor Locations

et al. 2016

View full text Add to dashboard Cite

show abstract

“…But the intracranial SFTs are more common in women around 50 years of age [ 6 ]. Most SFTs are benign, but about 10–15% of cases have malignant features such as recurrence or metastasis [ 7 ]. Patients with intracranial SFTs may have several non-specific symptoms associated with location of tumor or increased intracranial pressure, such as dizziness, headache, hemiplegia, gait disturbance, hearing or mental disorder [ 8 ].…”

Section: Discussionmentioning

confidence: 99%

Malignant Solitary Fibrous Tumor of the Right Cerebellum: A Case Report

et al. 2021

View full text Add to dashboard Cite

Solitary fibrous tumor is a very rare mesenchymal tumor that occurs mostly in the pleura, and there are few reported cases of a presence in the central nervous system, particularly in the cerebellum. In 2016, the WHO classified solitary fibrous tumors into grade I. In this article, we present a case of malignant solitary fibrous tumor recurring 8 years after surgery in a 63-year-old male. Magnetic resonance imaging showed low to intermediate mixed signal intensity on T1W1. Immunohistochemical staining positivity for Vimentin, CD99, CD34 and Bcl-2, it is consistent with the immunohistochemical characteristics of solitary fibrous tumor. We resected the patient’s tumor, and the patient was followed up for 3 months with no signs of recurrence. Solitary fibrous tumors are very rare in the central nervous system. Immunohistochemical staining positivity for CD34 and Bcl-2 is strongly expressed in most solitary fibrous tumor. Surgical resection is the preferred treatment. Due to the small number of cases, the biological behavior and prognosis of this tumor need to be further explored.

show abstract

“…1) Visual disturbance followed by headache is the most common presenting symptom of sellar SFT or HPC. [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] As with other suprasellar tumors, these tumors often compress the pituitary gland and stalk. Therefore, pituitary dysfunction is also a common symptom.…”

Section: Fig 2 Histology and Immunohistochemistry He Staining Shows Spindle-shaped Cells Arranged Around The Blood Vessels (A) (×200) Prementioning

confidence: 99%

“…To date, there are only 17 case reports of sellar and suprasellar SFT or HPC published in the English literature since 2001. [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] Most of these tumors reportedly occur in middle aged patients, with higher preponderance in male individuals, as shown in Table 1. We present the case of a sellar SFT or HPC in an 87-year-old woman who achieved treatment efficacy with fractionated gamma knife radiosurgery after partial resection of the tumor.…”

Section: Introductionmentioning

confidence: 99%

Solitary Fibrous Tumor or Hemangiopericytoma of the Sella in an Older Patient Treated with Partial Removal Followed by Fractionated Gamma Knife Radiosurgery

Thapa

Shimizu

Kitazono

et al. 2021

NMC Case Report Journal

View full text Add to dashboard Cite

Solitary fibrous tumor (SFT) or hemangiopericytoma (HPC) is a rare fibroblastic tumor of mesenchymal origin. SFT or HPC comprises <1% of all primary central nervous system tumors. SFT or HPC of the sellar or suprasellar region is even more unusual. We herein report a sellar SFT or HPC in an octogenarian who achieved favorable progress with partial removal followed by fractionated gamma knife radiosurgery. An 87-year-old woman presented with occasional headache and visual field defects. A rapidly growing tumor of the sella turcica was diagnosed. The patient underwent endoscopic transnasal transsphenoidal surgery; however, only partial resection of the tumor was possible, as it was fibrous and hard with increased vascularity. A histological examination confirmed the tumor to be grade II SFT or HPC. Two months after the resection, the residual tumor grew rapidly. Given the patient's advanced age, re-surgery was not the preferred option; thus, fractionated gamma knife radiosurgery (marginal dose, 30 Gy in five fractions) was performed. MRI and visual field examination performed 3 months after irradiation revealed tumor shrinkage and improvement in the visual field, respectively. One year and three months after irradiation, the tumor continued to shrink and her visual field had improved. Taking age into consideration, partial resection with fractionated gamma knife radiosurgery was the more appropriate choice for both local tumor control and the safety of the optic apparatus.

show abstract

Solitary fibrous tumor located in the sella turcica: A report of two cases and review of the literature

Cited by 11 publications

References 19 publications

Variable Solitary Fibrous Tumor Locations

Variable Solitary Fibrous Tumor Locations

Malignant Solitary Fibrous Tumor of the Right Cerebellum: A Case Report

Solitary Fibrous Tumor or Hemangiopericytoma of the Sella in an Older Patient Treated with Partial Removal Followed by Fractionated Gamma Knife Radiosurgery

Contact Info

Product

Resources

About