Solitary fibrous tumor surrounding the carotid sheath

Abstract

Solitary fibrous tumors (SFTs) are rare spindle cell neoplasms that are mostly found arising from the pleura. Although SFTs recently have been reported in other regions, they are rare in the head and neck and have often been misdiagnosed due to their rarity. SFTs are benign in most cases. Clinically, SFTs usually manifest as wellcircumscribed, slow-growing, smooth and painless masses. Symptoms are often minimal, although they may include sore throat, difficulty in swallowing, change of voice or trismus. CT-Scan and MRI are the most sensitive imaging procedures used. The treatment of choice is complete surgical excision of the lesion. Because recurrences have been noted up to 30 years after surgery, long-term follow up is mandatory. In this article, we present a case of a Solitary Fibrous Tumor arising in the parapharyngeal space in a 20-year-old man, involving the carotid sheath, treated by surgical excision with no recurrence after 1 year. The clinical presentation, surgical management and pathological findings are described.

Solitary fibrous tumor of the parapharyngeal space: report of 2 cases and a literature review

“…Preoperative biopsy of these lesions is not a standard and it is only reported in 5 studies, including our report [1,7,8,11]. Although an accurate diagnosis is challenging, there are several immunohistochemical markers, such as CD34, CD99, Bcl-2, SMA, EMA, factor XIIIa, and vimentin, that guide a preoperative diagnosis [11].…”

The Natural History of Parapharyngeal Solitary Fibrous Tumor/Hemangiopericytoma: A Case Report

“…Up to date, only 22 cases of SFT/HPC arising in this region were reported in English literature (summarized in Table 1). 6-27…”

Malignant Solitary Fibrous Tumor of the Renal Vein Presenting as a Giant Renal Artery Aneurysm: A Case Report and Review of Literature

“…There is one previous report 4 of SFT arising from the inferior vena cava, which was relatively small (4 cm) and benign appearing. There are several reports of it arising near vasculature structures (pericardium, carotid sheath, lower extremity), [17][18][19][20] but no other reports of SFT originating from the vessel itself. The vast majority of these tumors have had no malignant features and had varying sizes.…”