Solitary isolated neurofibroma of the soft palate

Kodiya, Aliyu Mohammed; Ngamdu, Yusuf Bukar; Sandabe, MB; Isa, Abdullahi; Garandawa, Hamman I.

doi:10.1093/jscr/rjs029

Cited by 7 publications

(5 citation statements)

References 9 publications

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“…Surgical excision is considered as the gold standard treatment for neurofibroma,11 especially when it causes dysphagia and respiratory obstruction. A similar case has been reported by Kodiya et al where a soft palate neurofibroma was successfully excised after the patient being tracheostomised 12. Microscopic examination usually revealed a non-encapsulated, spindle cell lesion in the subepithelium with intact overlying stratified squamous epithelium and the wavy nuclei in the spindle cells are arranged in loose fascicles admixed with bundles of collagen without cellular atypia.…”

Section: Discussionsupporting

confidence: 73%

Solitary vallecular neurofibroma presenting with respiratory obstruction: an unusual presentation

Pradhan¹,

Mallick

Samal

et al. 2018

BMJ Case Reports

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An occurrence of vallecular neurofibroma with airway obstruction is extremely rare and to the best of our knowledge, no case report has been documented in the literature to date. Although microlaryngeal surgery with cold knife excision is the standard surgical procedure offered to patients of vallecular lesions, it can be successfully managed with the help of endoscopic coblation as later can provide a bloodless surgical field preventing the unmet need for the tracheostomy and reducing the postoperative morbidities.

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Section: Discussionsupporting

confidence: 73%

Solitary vallecular neurofibroma presenting with respiratory obstruction: an unusual presentation

Pradhan¹,

Mallick

Samal

et al. 2018

BMJ Case Reports

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“…[9] Its occurrence is between the age of 10 months and 70 years old, but it is common mostly during the third decade of life. [14] In a case reported by Dalili et al (2012) there was mandible, maxilla, and orbit concurrent involvement. Radiographically, the lesion showed bone destruction in the maxilla, and the walls of right maxillary sinus displacement into the antral cavity.…”

Section: Discussionmentioning

confidence: 97%

“…[1] The gold standard treatment of solitary neurofibroma is complete surgical excision; similar to the one we performed for our case. [14] Radiotherapy alone is not adequate, but it can reduce the tumor size and growth. [14,18] Diode lasers presented good results for small and accessible tumors.…”

Section: Discussionmentioning

confidence: 99%

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Solitary central neurofibroma of the maxilla: A Case Report

Danesteh

Sadeghzade

Jafarpour

2020

BDS

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Neurofibroma is a benign tumor which rarely occurs in the oral cavity. Generally, oral neurofibroma is part of a neurofibromatosis type-1 like syndrome (Von Recklinghausen’s disease) and rarely occurs as a solitary lesion of oral cavity. Up to now, few cases have been reported with the solitary neurofibromas of tongue and submandibular gland. The tumor can also be rarely located centrally in the bone. This research presents a central neurofibroma case in the maxillary bone which has no relationship with the neurofibromatosis. Keywords Central neurofibroma; Neurofibromatosis; Solitary neurofibroma; Von Recklinghausen’s disease.

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“…Some pedunculated lesions were not included in clinical diagnostic hypothesis, as fibroma and hyperplasia (12), because of the fast-growing enlargement of the nodule. Neural tumors also occur on the palate, and only in rare occasions can be pedunculated, as solitary neurofibroma (13). Moreover, the pedunculated morphology was decisive to rule out all salivary gland tumors from the list of differential clinical diagnoses.…”

Section: Discussionmentioning

confidence: 99%

Oral Adenosquamous Carcinoma Mimicking a Pyogenic Granuloma: A Challenging Diagnosis

Anbinder

Faig

Carta

et al. 2015

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

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Adenosquamous carcinoma is an aggressive variant of squamous cell carcinoma. This report describes a case of adenosquamous carcinoma with clinical features of a benign lesion and discusses the differential diagnoses, especially regarding histopathological and immunohistochemical analyses. A 45-year-old male was referred to our outpatient clinic complaining about a rapid-growing enlargement in hard palate. Clinical examination revealed an erythematous and pedunculated nodule with lobulated non-ulcerated surface. Excisional biopsy was performed following clinical diagnosis of pyogenic granuloma. Histologically, the specimen consisted of areas characterizing both welldifferentiated squamous cell carcinoma and true adenocarcinoma. After a broad list of immunohistochemical markers was evaluated (AE1/AE3, CEA, CK5, CK7, CK8/18, p53, p63 and Ki67), the diagnosis of adenosquamous carcinoma was rendered and the patient referred to complementary surgery. Adenosquamous carcinoma represents a challenge in diagnostic routine due to its rarity, diverse range of clinical presentations and histological features. Furthermore, classical clinical benign features may be present in malignant lesions; hence the submission of every surgical specimen to histological analysis is mandatory to provide the patient the adequate treatment.

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Solitary isolated neurofibroma of the soft palate

Cited by 7 publications

References 9 publications

Solitary vallecular neurofibroma presenting with respiratory obstruction: an unusual presentation

Solitary vallecular neurofibroma presenting with respiratory obstruction: an unusual presentation

Solitary central neurofibroma of the maxilla: A Case Report

Oral Adenosquamous Carcinoma Mimicking a Pyogenic Granuloma: A Challenging Diagnosis

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