We construct K-solitons of the focusing energy-critical nonlinear wave equation in five-dimensional space, i.e. solutions u of the equation such thatwhere K ≥ 2 and for any k ∈ {1, . . . , K}, W k is the Lorentz transform of the explicit standing soliton W (x) = (1 + |x| 2 /15) −3/2 , with any speed ℓ k ∈ R 5 , |ℓ k | < 1 satisfying ℓ k ′ = ℓ k for k ′ = k, and an explicit smallness condition. The proof extends the refined method of construction of asymptotic multi-solitons from [11,12].