Solubilities of the xanthines caffeine, theophylline and theobromine in supercritical carbon dioxide

Purification method development for chiral separation in supercritical fluid chromatography with the solubilities in supercritical fluid chromatographic mobile phases

“…Measuring solubility in supercritical fluidic conditions has been one of the major research topics of the supercritical fluid extraction field [21][22][23]. Solubility has been determined by using a phase monitor, observing formation of a single phase or by directly connecting a saturated chamber to a detection device such as UV or flame ionization [24][25][26][27].…”

A combined determination of phase diagrams of asymmetric binary mixtures by equations of state and transitiometry

“…Phase equilibria of solid caffeine with supercritical carbon dioxide had been measured by Ebeling and Franck [30] as well as by Johannsen and Brunner [35]. The data sets do not match very well; the latter set shows considerable scatter.…”

Impact of ethanol addition on the solubility of various soybean isoflavones in supercritical carbon dioxide and the effect of glycoside chain in isoflavones

“…Supercritical carbon dioxide has been employed as the favorite extraction medium for many food functional components, i.e., caffeine (Iwai et al, 2006;Johannsen and Brunner, 1994;Kopcak and Mohamed, 2005;Li et al, 1991), capsaicin (Duarte et al, 2002;de la Fuente et al, 2005), carotenoids (Cygnarowicz et al, 1990;de la Fuente et al, 2006;Škerget et al, 1995;Subra et al, 1997), polyphenol (Berna et al, 2001;Cháfer et al, 2002;Nunes et al, 2007;Wang and Cheng, 2005), aspirin (Huang et al, 2005), and coenzyme Q10 (Matias et al, 2004).…”