Solubility of Zaltoprofen in Five Binary Solvents at Various Temperatures: Data Determination and Thermodynamic Modeling

Sun, Renren; Wan, Yameng; He, Hui; Sha, Jiao; Li, Tao; Ren, Baozeng

doi:10.1021/acs.jced.9b01180

Cited by 7 publications

(4 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the article published by our research team, 16 the method was used to measure the solubility of sodium chloride in water. 17 The difference between the experimental value and the literature value was within 0.5%. It was proved that the research methods and experimental instruments in this study are accurate and reliable.…”

Section: Solubility Measurementmentioning

confidence: 65%

See 1 more Smart Citation

Solubility Measurement and Hansen Solubility Parameter of Forchlorfenuron in 12 Organic Pure Solvents at Various Temperatures

Wang

et al. 2022

J. Chem. Eng. Data

Self Cite

View full text Add to dashboard Cite

In this work, the solubility of forchlorfenuron [N-(2-chloro-4pyridinyl)-N′-phenylurea (CPPU)] in 12 selected pure solvents (n-pentanol, nbutanol, n-propanol, ethanol, methanol, ethyl acetate, n-propyl acetate, n-butyl acetate, i-propyl acetate, i-butyl acetate, i-amyl acetate, and acetone) was determined under the conditions of 0.1 MPa and 278.15−323.15 K using the laser detection method. The results indicate that the solubility of CPPU in the selected solvents is proportional to temperature. Five models (Two-Suffix Margules, NRTL, λh, Universal Quasi-Chemical, and the modified Apelblat) were selected to fit the solubility data of CPPU in pure solvents. By comparison, it is found that the modified Apelblat model has a better fitting effect. The solubility rules of CPPU in different solvents were analyzed using Hansen solubility parameters and polarity. The solvent effect of CPPU solubility in different solvents studied was discussed using the KAT-LSER model. The above studies can supply some primary data for the crystallization process of CPPU.

show abstract

Section: Solubility Measurementmentioning

confidence: 65%

“…The laser detection method has high precision. In the article published by our research team, the method was used to measure the solubility of sodium chloride in water . The difference between the experimental value and the literature value was within 0.5%.…”

Section: Experimental Sectionmentioning

confidence: 99%

Solubility Measurement and Hansen Solubility Parameter of Forchlorfenuron in 12 Organic Pure Solvents at Various Temperatures

Wang

et al. 2022

J. Chem. Eng. Data

Self Cite

View full text Add to dashboard Cite

show abstract

“…The Sun model − can be expressed as follows ln nobreak0em0.25em⁡ x 1 = A 1 + A 2 T + A 3 x 2 0 + A 4 x 2 0 T + A 5 ( x 2 0 ) 2 T + A 6 ( x 2 0 ) 3 T + A 7 ( x 2 0 ) 4 T where x 1 is the mole fraction of 3-aminophenol, T is the absolute thermodynamic temperature, x 2 0 represents the initial molecular fraction composition of a binary solvent mixture without solutes, and A 1 to A 9 are the model parameters.…”

Section: Theoretical Modelsmentioning

confidence: 99%

Solubility Determination, Modeling, and Thermodynamic Analysis of 3-Aminophenol in Ten Monosolvents and Three Binary Mixed Solvents

Wu,

Xue,

Wang

et al. 2024

J. Chem. Eng. Data

View full text Add to dashboard Cite

The solubilities of 3-aminophenol in monosolvents (ethyl acetate, isopropyl acetate, n-butyl acetate, amyl acetate, 1,2-dichloroethane, trichloromethane, benzene, 1,4-dioxane, tetrahydrofuran, and acetonitrile) and binary solvent mixtures (1,4-dioxane + water, tetrahydrofuran + water, and acetonitrile + water) were determined by a static gravimetric method at temperatures ranging from 283.15 to 328.15 K under atmospheric pressure. The solubility of 3-aminophenol in all solvent systems is positively correlated with temperature. In monosolvents, the solubility order of 3-aminophenol was as follows: THF > 1,4-dioxane > acetonitrile > ethyl acetate > isopropyl acetate > n-butyl acetate > amyl acetate > 1,2-dichloroethane > trichloromethane > benzene. The maximum solubility value occurred in 1,4-dioxane (x 1 = 0.3700 mol·mol–1, T = 328.15 K), and the minimum solubility value occurred in benzene (x 1 = 0.0005505 mol·mol–1, T = 288.15 K). In general, the solubility of 3-aminophenol in 1,4-dioxane + water and THF + water is greater than that in acetonitrile + water. There is a cosolvency phenomenon of 3-aminophenol in the solvents of 1,4-dioxane + water and acetonitrile + water. The experimental solubility data were correlated by the modified Apelblat model, the Yaws model, the λh model, the Sun model, the modified Jouyban–Acree model, and the Wilson model. The modified Apelblat model best fitted the experimental data among all of the selected models in monosolvents (with relative average deviation (RAD) and root-mean-square deviation (RMSD) less than 0.0156 and 0.001212, respectively) and binary solvent mixtures (with RAD and RMSD less than 0.0102 and 0.001408, respectively). Based on the experimental data of the solubility of 3-aminophenol in mono and binary solvents, the Wilson model was used to calculate the dissolution properties (Δdis H, Δdis S, and Δdis G). The results indicate that the dissolution process of 3-aminophenol is endothermic, entropy-increasing, and spontaneous. All of the selected models for both mono and binary solvents provide satisfactory correlation results.

show abstract

“…Crystallization, as the most important purification step in industry, especially in the pharmaceutical industry, has received more and more attention . Solubility can provide basic data for the selection of crystallization methods and processes, − while knowledge of the solubility of substances in different solvents provides a reference for the optimization of crystal morphology, − the development of new crystal forms, to solve the problems of low bioavailability, and medical solutions. Therefore, to select a suitable solvent and optimize the crystallization process, the systematic determination of solubility data is of great significance.…”

Section: Introductionmentioning

confidence: 99%

Measurement and Correlation of Solubility Data for Cytosine in Fourteen Pure Solvents from 288.15 to 328.15 K

et al. 2022

View full text Add to dashboard Cite

The solubility of cytosine in fourteen pure solvents at 288.15–328.15 K was determined by the gravimetric method, and the solubility data were correlated using the modified Apelblat equation, the λh model, and the van′t Hoff equation. The relative deviation (RD), average relative deviation (ARD), and root-mean-square deviation (RMSD) values of the above models were calculated. The results showed that the three models have a good correlation with experimental data. Especially, the modified Apelblat equation had the best correlation effect on solubility. Theoretical knowledge of solubility is essential for the crystallization of cytosine.

show abstract

Solubility of Zaltoprofen in Five Binary Solvents at Various Temperatures: Data Determination and Thermodynamic Modeling

Cited by 7 publications

References 21 publications

Solubility Measurement and Hansen Solubility Parameter of Forchlorfenuron in 12 Organic Pure Solvents at Various Temperatures

Solubility Measurement and Hansen Solubility Parameter of Forchlorfenuron in 12 Organic Pure Solvents at Various Temperatures

Solubility Determination, Modeling, and Thermodynamic Analysis of 3-Aminophenol in Ten Monosolvents and Three Binary Mixed Solvents

Measurement and Correlation of Solubility Data for Cytosine in Fourteen Pure Solvents from 288.15 to 328.15 K

Contact Info

Product

Resources

About