Solution behavior of quenched or strongly charged polyampholytes  in aqueous-salt solutions

Toleutay, Gaukhar; Shakhvorostov, Alexey; Kabdrakhmanova, Sana; Kudaibergenov, Sarkyt E.

doi:10.31489/2019ch2/35-44

Cited by 11 publications

(11 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One of the open problems in the behavior of synthetic polyampholytes is to shed light on the internal globular structure of amphoteric macromolecules, which are considered to be densely folded three‐dimensional nucleations consisting of a core surrounded by a hydrophilic edge from which monomers force out solvents. The discovery of a highly ordered structure of synthetic water‐soluble and water‐swelling polyampholytes, whether in a solution or solid state, at the isoelectric point (IEP) opens up a challenging task, which requires theoretical, computational, and simulation approaches in order to achieve a better understanding of the driving forces behind the self‐organizing structure of polyampholytes at the IEP 109 …”

Section: Future Advances In Polyampholytesmentioning

confidence: 99%

Synthetic and natural polyampholytes: Structural and behavioral similarity

Kudaibergenov

2020

Polymers for Advanced Techs

View full text Add to dashboard Cite

The ability of synthetic polyampholytes to adopt globular, coil, helix, and stretched conformations and to exhibit coil–globule, helix–coil, liquid–liquid, sol–gel phase transitions with respect to internal (structure, composition, charge distribution, hydrophobicity, hydrophilicity, and so forth) and external factors (pH, temperature, ionic strength, thermodynamic quality of solvents, and so forth) is very important in duplicating the structural hierarchy of proteins. In this review, the structural and behavioral similarities between synthetic and natural polymers are analyzed, primarily concentrating on synthetic polyampholytes, amphoteric polypeptides, and intrinsically disordered proteins (IDPs) in order to demonstrate the close relationship. The application aspects of polyampholytes and future opportunities are briefly outlined.

show abstract

Section: Future Advances In Polyampholytesmentioning

confidence: 99%

Synthetic and natural polyampholytes: Structural and behavioral similarity

Kudaibergenov

2020

Polymers for Advanced Techs

View full text Add to dashboard Cite

show abstract

“…The antipolyelectrolyte effect was confirmed by experimental results of authors [ 21 , 22 , 23 ] obtained for both annealed and quenched polyampholytes in solution and gel state. Earlier, the same research team showed that the intrinsic viscosity of charged-balanced polyampholyte APTAC 50 -co-AMPS 50 increases in saline solution, another example of the antipolyelectrolyte effect [ 24 ]. The behavior of charge-balanced amphoteric nanogel NIPAM 90 -APTAC 5 -AMPS 5 at the IEP (or in a quasi-neutral state) is in good agreement with the theory of Khokhlov et al [ 25 ], e.g., the swelling of polyampholyte gel near the IEP should increase with the increase in the ionic strength of the solution.…”

Section: Resultsmentioning

confidence: 99%

Temperature and Salt Responsive Amphoteric Nanogels Based on N-Isopropylacrylamide, 2-Acrylamido-2-methyl-1-propanesulfonic Acid Sodium Salt and (3-Acrylamidopropyl) Trimethylammonium Chloride

et al. 2022

View full text Add to dashboard Cite

Polyampholyte nanogels based on N-isopropylacrylamide (NIPAM), (3-acrylamidopropyl) trimethylammonium chloride (APTAC) and 2-acrylamido-2-methyl-1-propanesulfonic acid sodium salt (AMPS) were synthesized via conventional redox-initiated free radical copolymerization. The resultant nanogels of various compositions, specifically [NIPAM]:[APTAC]:[AMPS] = 90:5:5; 90:7.5:2.5; 90:2.5:7.5 mol.%, herein abbreviated as NIPAM90-APTAC5-AMPS5, NIPAM90-APTAC7.5-AMPS2.5 and NIPAM90-APTAC2.5-AMPS7.5, were characterized by a combination of 1H NMR and FTIR spectroscopy, TGA, UV–Vis, DLS and zeta potential measurements. The temperature and salt-responsive properties of amphoteric nanogels were studied in aqueous and saline solutions in a temperature range from 25 to 60 °C and at ionic strengths (μ) of 10−3 to 1M NaCl. Volume phase transition temperatures (VPTT) of the charge-balanced nanogel were found to reach a maximum upon the addition of salt, whereas the same parameter for the charge-imbalanced nanogels exhibited a sharp decrease at higher saline concentrations. A wide bimodal distribution of average hydrodynamic sizes of nanogel particles had a tendency to transform to a narrow monomodal peak at elevated temperatures and higher ionic strengths. According to the DLS results, increasing ionic strength results in the clumping of nanogel particles.

show abstract

“…Schematic representation of a core‐shell structure, and the behavior of QPA in aqueous‐salt solutions. Reproduced from Reference 45 with permission from Bulletin of Karaganda University…”

Section: Properties Of Quenched Polyampholytes In Water and Aqueous‐salt Solutionsmentioning

confidence: 99%

“…Another specific property of QPA is the antipolyelectrolyte effect in response to salt addition 25‐27 . Charge‐balanced and charge‐unbalanced QPA consisting of a core (polyampholyte regime) and shell (polyelectrolyte regime) structure show antagonism in aqueous salt solutions 45,46 . Addition of low‐molecular‐weight salts tends to shrink the shell part and to swell the core part.…”

Section: Introductionmentioning

confidence: 99%

Behaviors of quenched polyampholytes in solution and gel state

Kudaibergenov

Okay

2020

Polymers for Advanced Techs

View full text Add to dashboard Cite

The quenched or strongly charged polyampholytes represent amphoteric macromolecules consisting of static positive and negative charges that slightly depend on pH. Here, the behavior of linear and cross‐linked quenched polyampholytes (QPA) in aqueous salt solutions is reviewed together with their stimuli‐responsive character as functions of temperature and ionic strength. The volume‐phase, swelling‐deswelling, self‐healing, viscoelastic, and mechanical properties of QPA gels are also discussed. Complexation of QPA with dye molecules, surfactants, and proteins is outlined. Application aspects of QPA cover biotechnology, biomedicine, oil recovery, desalination, etc.

show abstract

Solution behavior of quenched or strongly charged polyampholytes in aqueous-salt solutions

Cited by 11 publications

References 0 publications

Synthetic and natural polyampholytes: Structural and behavioral similarity

Synthetic and natural polyampholytes: Structural and behavioral similarity

Temperature and Salt Responsive Amphoteric Nanogels Based on N-Isopropylacrylamide, 2-Acrylamido-2-methyl-1-propanesulfonic Acid Sodium Salt and (3-Acrylamidopropyl) Trimethylammonium Chloride

Behaviors of quenched polyampholytes in solution and gel state

Contact Info

Product

Resources

About