Solventless Synthesis of 2,4,10a‐Triaryl‐1,10a‐dihydro‐2H‐pyrazino[2,1‐b][1,3]benzoxazole.

Abstract

Pyrazine derivatives R 0550Solventless Synthesis of 2,4,10a-Triaryl-1,10a-dihydro-2H-pyrazino[2,1-b][1,3]benzoxazole. -(RAVINDRAN, G.; MUTHUSUBRAMANIAN*, S.; SELVARAJ, S.; PERUMAL, S.; Indian J.

A convenient one pot synthesis of highly substituted piperidines through a Michael addition-aldol cyclization sequence

“…In continuation to our exploration on the synthetic utility of N,N-diphenacylaniline, [15][16][17][18] we investigated the reaction of this substrate with chalcones in the presence of a base. A mixture of 2-[(2-oxo-2-arylethyl)anilino]-1-aryl-1-ethanones 1 with different arylidene acetophenone 2 and a catalytic amount of sodium ethoxide was taken in a glass tube and mixed thoroughly.…”