2004
DOI: 10.1016/j.pnpbp.2004.08.003
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Somatodendritic and postsynaptic serotonin-1A receptors in the attenuation of haloperidol-induced catalepsy

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Cited by 36 publications
(20 citation statements)
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“…This is in a good agreement with the published data on anti-cataleptic action of 5-HT 1A receptor selective agonists (Haleem et al, 2004) and on localization of the main QTL for catalepsy in the region of the 13 chromosome that includes 5-HT 1A receptor gene (Kulikov et al, 2003). Important is the advantage of PCR with gel-detection of products that it does not require producing expensive hybridization probes and, consequently, studies using this method can be performed almost in any laboratory.…”
Section: Discussionsupporting
confidence: 89%
“…This is in a good agreement with the published data on anti-cataleptic action of 5-HT 1A receptor selective agonists (Haleem et al, 2004) and on localization of the main QTL for catalepsy in the region of the 13 chromosome that includes 5-HT 1A receptor gene (Kulikov et al, 2003). Important is the advantage of PCR with gel-detection of products that it does not require producing expensive hybridization probes and, consequently, studies using this method can be performed almost in any laboratory.…”
Section: Discussionsupporting
confidence: 89%
“…It is unclear why only partial antagonism was observed. It is possible that full reversal of quinpirole's effect would be achieved with higher doses of the antagonists than those used in the present experiments, although the use of substantially higher doses would incur the risk of contaminating timing performance with non-specific behavioural effects such as stereotypy and catalepsy (Wanibuchi and Usuda 1990;Fowler and Lion 1998;Haleem et al 2004). It is possible, however, that the partial antagonism of quinpirole's effect may reflect an action of quinpirole at another receptor in addition to D 2 -like receptors.…”
Section: Discussionmentioning
confidence: 92%
“…HPLC-EC method as before [30][31][32] was used to determine the levels of 5-HT and 5-HIAA in brain. 4 mm diameter and 150 mm length Shim-pack ODS column of 5 µm was utilized.…”
Section: Estimations Of Whole Brain 5-ht and 5-hiaa By Hplc-ec Methodsmentioning
confidence: 99%