Somatosensory lateralization in the newborn brain

Erberich, Stephan G.; Panigrahy, Ashok; Friedlich, Philippe; Seri, István; Nelson, Marvin D.; Gilles, Floyd H.

doi:10.1016/j.neuroimage.2005.07.024

Cited by 90 publications

(81 citation statements)

References 37 publications

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“…41,42 Erberich et al recently used fMRI to study cortical BOLD signal induced by passive extension and flexion of the hand in 24 preterm and term infants; a group of 6 term infants aged 3-9 months served as controls. 45 In contrast to the contralateral localization of BOLD response found in the older control infants, BOLD signal in response to unilateral stimulation was found in the somatosensory areas in the precentral and postcentral gyri of both hemispheres of the neonatal group at term-equivalent age.…”

Section: Functional Mri Studies Assess Sensory Modalities In the Premmentioning

confidence: 63%

Injury and recovery in the developing brain: evidence from functional MRI studies of prematurely born children

Ment

Constable

2007

Nat Rev Neurol

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SUMMARYFunctional MRI (fMRI) might provide important insights into emerging data that suggest that recovery from injury can occur in the brains of children born prematurely. Strategies employing auditory stimulation demonstrate blood-oxygen-level-dependent (BOLD) activation in preterm infants as young as 33 weeks' gestational age, and reliable BOLD signal in response to visual stimulation occurs at term-equivalent age. Strategies based on fMRI are particularly suited to the study of language and memory, and emerging data are likely to provide insights into perplexing reports that have demonstrated improving cognitive scores but persistent volumetric and microstructural changes in frontotemporal language systems in the prematurely born. Even when sex, gestational age and early medical and environmental interventions are taken into account, fMRI data from several investigators suggest the engagement of alternative neural networks for language and memory in the developing preterm brain.

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Section: Functional Mri Studies Assess Sensory Modalities In the Premmentioning

confidence: 63%

Injury and recovery in the developing brain: evidence from functional MRI studies of prematurely born children

Ment

Constable

2007

Nat Rev Neurol

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“…To this end, task-evoked fMRI signal changes in response either to a reversing checkerboard (22) or to a flickering light (23) were observed in the primary visual cortex along the calcarine sulcus in sleeping infants. Moreover, somatosensory areas in sedated infants were activated bilaterally in response to a unilateral, passive extension and flexion of the hand (24). In the case of auditory perception, activity in the temporal lobe has been reported for both simple tone stimuli in sleeping infants (25) as well as for speech processing in awake infants (26,27).…”

Section: Discussionmentioning

confidence: 98%

Resting-state networks in the infant brain

Fransson

Skiöld²,

Horsch³

et al. 2007

Proc. Natl. Acad. Sci. U.S.A.

621

527

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In the absence of any overt task performance, it has been shown that spontaneous, intrinsic brain activity is expressed as systemwide, resting-state networks in the adult brain. However, the route to adult patterns of resting-state activity through neuronal development in the human brain is currently unknown. Therefore, we used functional MRI to map patterns of resting-state activity in infants during sleep. We found five unique resting-states networks in the infant brain that encompassed the primary visual cortex, bilateral sensorimotor areas, bilateral auditory cortex, a network including the precuneus area, lateral parietal cortex, and the cerebellum as well as an anterior network that incorporated the medial and dorsolateral prefrontal cortex. These results suggest that resting-state networks driven by spontaneous signal fluctuations are present already in the infant brain. The potential link between the emergence of behavior and patterns of resting-state activity in the infant brain is discussed.development ͉ functional MRI ͉ spontaneous activity R ecent research on functional connectivity in the brain, in particular during resting-state conditions, has come to focus on low-frequency (Ͻ0.1 Hz), spontaneous fluctuations in the functional MRI (fMRI) signal. Discovered by Biswal et al. (1), it has been shown that systemwide networks in the resting brain are synchronized in time through intrinsic low-frequency signal fluctuations. Whereas early fMRI studies demonstrated synchronicity of intrinsic brain activity across hemispheres in primary sensory cortices (2, 3), succeeding studies have shown temporal synchronization in a resting-state network encompassing higher-order cortices (4). A systematic investigation of resting-state activity in the adult human brain was recently presented by Damoiseaux et al. (5). Using independentcomponent analysis (ICA), a data-driven explorative data analysis approach, they showed that there are numerous networks in the brain that are driven by spontaneous activity. Besides networks that are in part or fully described by the previously reported default mode (6) and task-positive network (7, 8), they found consistent patterns of resting-state activity in the visual cortex, sensorimotor areas, auditory areas, as well as extrastriate brain regions. These findings together with previous investigations on spontaneous activity suggest that the assumption that the brain during rest is idle and waiting to be triggered and respond to changes in the environment is not strictly valid. Rather, in addition to responding to changes in external stimuli or tasks, the brain is characterized by intrinsic dynamics in the form of coherent and spontaneous fluctuations, clustered together in networks that are credible from an anatomical and functional perspective.Interestingly, recent studies have presented evidence that spontaneous activity is relevant for human behavior. Momentary lapses of attention, affecting goal-oriented behavior on a global/ local selective attention task, were related to a fai...

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“…Much of our present-day knowledge about brain-behavior relationships shortly after birth comes from task-based fMRI studies (Allievi et al, 2016;Anderson et al, 2001;Arichi et al, 2013Arichi et al, , 2012Arichi et al, , 2010Born et al, 1996;Dehaene-Lambertz et al, 2010, 2002Erberich et al, 2006;Heep et al, 2009;Konishi et al, 2002;Morita et al, 2000). These studies have provided important background on the brain's responses to sensory input during the earliest phases of development of brain-behavior interactions.…”

Section: Functional Connectivity and Behavioral Counterpartsmentioning

confidence: 99%

“…These studies have provided important background on the brain's responses to sensory input during the earliest phases of development of brain-behavior interactions. Adult-like activation patterns were observed in response to a variety of sensory stimuli, including tactile and proprioceptive stimulation (passive hand movement) (Arichi et al, , 2010Erberich et al, 2006), auditory (Anderson et al, 2001), olfactory (the odor of infant formula) ) and visual input. fMRI studies in two-to three-month-old infants demonstrated leftlateralized activation of perisylvian regions including the superior temporal gyrus, angular gyrus and Broca's area in response to native-language speech (Dehaene-Lambertz et al, 2006, 2002.…”

Section: Functional Connectivity and Behavioral Counterpartsmentioning

confidence: 99%

The emergence of functional architecture during early brain development

2017

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Early human brain development constitutes a sequence of intricate processes resulting in the ontogeny of functionally operative neural circuits. Developmental trajectories of early brain network formation are genetically programmed and can be modified by epigenetic and environmental influences. Such alterations may exert profound effects on neurodevelopment, potentially persisting throughout the lifespan. This review focuses on the critical period of fetal and early postnatal brain development. Here we collate findings from neuroimaging studies, with a particular focus on functional MRI research that interrogated early brain network development in both health and high-risk or disease states. First, we will provide an overview of the developmental processes that take place from the embryonic period through early infancy in order to contextualize brain network formation. Second, functional brain network development in the typically developing brain will be discussed. Third, we will touch on prenatal and perinatal risk factors that may interfere with the trajectories of functional brain wiring, including prenatal substance exposure, maternal mental illness and preterm

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Somatosensory lateralization in the newborn brain

Cited by 90 publications

References 37 publications

Injury and recovery in the developing brain: evidence from functional MRI studies of prematurely born children

Injury and recovery in the developing brain: evidence from functional MRI studies of prematurely born children

Resting-state networks in the infant brain

The emergence of functional architecture during early brain development

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