In this paper the Burzynski criterion, which was introduced for isotropic pressure-dependent materials, is modified for anisotropic pressure-dependent materials in plane-stress condition. The modified criterion can be calibrated with 10 experimental data points such as tensile stress at 0°, 45°and 90°, compressive stress at 0°and 90°and R-values in tensile stress at 0°, 45°and 90°from rolling direction and also biaxial tensile stress and tensile R-value. To identify the anisotropic parameters an error function is set up through comparison of the predicted yield stresses and R-values with those from experiments. Then the Downhill simplex method is applied to solve 10 high-nonlinearity equations. Finally, considering Al 2008-T4 (BCC), Al 2090-T3 (FCC), AZ31 (HCP) and also Mg-0.5% Th alloy, Mg-4% Li alloy, pure textured magnesium, textured magnesium and Ti-4Al-1/4O 2 , which are HCP materials with e p ¼ 1%; 5%; 10% as case studies and comparing the results for the modified Burzynski criterion with experiments, it is shown that the Burzynski criterion is appropriate for pressure-dependent anisotropic materials with proper accuracy.