“…These effects are purportedly elicited by afferents in skin, muscle, joint, and neurovascular structures in response to the mechanical stimulus, producing centrally-mediated (especially periaqueductal grey) pain inhibition, reduced mechanosensitivity, either sympathetic excitation or inhibition, and either increased or decreased ROM [7][8][9][10]. Effects have been shown to extend remotely to influence the shoulder [11][12][13] and elbow [14][15][16][17]. In addition to intrinsic shoulder structures with causation for shoulder pain [18][19][20], extrinsic structures like the cervical [11,12,21] and thoracic spines [22][23][24][25], and upper ribs [26] have been implicated.…”