Some health benefits of physical activity. The Framingham Study

Kannel, W. B.

doi:10.1001/archinte.139.8.857

Cited by 347 publications

(333 citation statements)

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“…Alcohol consumption was measured in ounces per month, but only in eight examinations (2,4,7,19,(20)(21)(22)(23). Physical activity was collected as a continuous score, derived from the number of hours individuals spend daily at different activity levels (16) , in four examinations (4,11,12,19).…”

Section: Measurement Of Other Variablesmentioning

confidence: 99%

The duration of obesity and the risk of type 2 diabetes

Abdullah

Stoelwinder

Shortreed

et al. 2010

Public Health Nutr.

150

115

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Objective: The evidence for the association between obesity and the risk of type 2 diabetes has been derived mainly from the analysis of the degree of obesity. The role of the duration of obesity as an independent risk has not been fully explored. The objective of the present study was to investigate the association between the duration of obesity and the risk of type 2 diabetes. Design: Prospective cohort study. Setting: The Framingham Heart Study (FHS), follow-up from 1948 to 1998. Subjects: A total of 1256 FHS participants who were free from type 2 diabetes at baseline, but were obese on at least two consecutive of the study's twenty-four biennial examinations, were included. Type 2 diabetes status was collected throughout the 48 years of follow-up of the study. The relationship between duration of obesity and type 2 diabetes was analysed using time-dependent Cox models, adjusting for a number of covariates. Results: The unadjusted hazard ratio (HR) for the risk of type 2 diabetes for men was 1?13 (95 % CI 1?09, 1?17) and for women was 1?12 (95 % CI 1?08, 1?16) per additional 2-year increase in the duration of obesity. Adjustment for sociodemographic variables, family history of diabetes, health behaviour and physical activity made little difference to these HR. For women the evidence of a doseresponse relationship was less clear than for men, particularly for women with an older age at obesity onset. Conclusions: The duration of obesity is a relevant risk factor for type 2 diabetes, independent of the degree of BMI.

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Section: Measurement Of Other Variablesmentioning

confidence: 99%

The duration of obesity and the risk of type 2 diabetes

Abdullah

Stoelwinder

Shortreed

et al. 2010

Public Health Nutr.

150

115

View full text Add to dashboard Cite

show abstract

“…The subjects were informed about the experimental protocol, and signed consent was obtained. Subjects were also required to pass a physical exam and fill out a physical activity readiness form before participation (19 Subjects were studied during the follicular phase of their menstrual cycles and included some subjects taking and some subjects not taking birth control pills. Inclusion and exclusion criteria were identical to those used in our previously published study (13).…”

Section: Effect Of Exercise Intensity On Dietary Fat Usementioning

confidence: 99%

Prior Exercise Increases Dietary Oleate, but Not Palmitate Oxidation

2003

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VOTRUBA, SUSANNE B., RICHARD L. ATKINSON, AND DALE A. SCHOELLER. Prior exercise increases dietary oleate, but not palmitate oxidation. Obes Res. 2003; 11:1509 -1518. Objective: Higher levels of physical activity have been associated with body weight maintenance, but previous work in our laboratory suggests that this is not purely related to energy balance. We hypothesize that this may be related to the partitioning of dietary fat between oxidation and storage. Research Methods and Procedures: Healthy women (age 24 Ϯ 1 years, BMI ϭ 21.2 Ϯ 0.4 kg/m 2 ) were recruited to participate in rest (n ϭ 10) or exercise sessions of light (n ϭ 11), moderate (n ϭ 10), and heavy (n ϭ 7) exercise. All exercises (1250 kJ above rest) were performed on a stationary cycle inside of a whole-body calorimeter. Results: Cumulative oxidation of [1-13 C]oleate was significantly greater after light (45 Ϯ 3%), moderate (54 Ϯ 4%), and heavy (51 Ϯ 4%) exercise than that with rest (33 Ϯ 3%) (p ϭ 0.0008). Cumulative oxidation of [d 31 ]palmitate did not differ among trials (12 Ϯ 2%, 14 Ϯ 1%, 17 Ϯ 2%, and 14 Ϯ 2% for rest, light, moderate, and heavy, respectively; p ϭ 0.30). Discussion: Exercise standardized for energy expenditure increases monounsaturated fat oxidation more than saturated fat oxidation and that the increase occurs regardless of intensity. Recommendations for physical activity for the purposes of weight control may be specific for dietary fat composition.

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“…Alcohol use was dichotomized as current drinker vs. nondrinker. Our physical activity score was constructed from information collected with a modified version of the Harvard Alumni Physical Activity questionnaire (21) and based on the methodology used in the Framingham Heart Study (22). Subjects were questioned about the hours per day (mean of a regular weekday and a regular weekend day) spent in sleep, sedentary, light, moderate, and vigorous activities, with interviewer probing to ensure that the total hours added up to 24.…”

Section: Data Collectionmentioning

confidence: 99%

Total and Central Obesity among Elderly Hispanics and the Association with Type 2 Diabetes

Bermúdez

Tucker

2001

Obesity Research

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BERMUDEZ, ODILIA I. AND KATHERINE L. TUCKER. Total and central obesity among elderly Hispanics and the association with type 2 diabetes. Obes Res. 2001;9:443-451. Objective: To report the prevalence of total and central obesity in a representative sample of Puerto Rican and Dominican elders in Massachusetts, to compare them with a neighborhood-based group of non-Hispanic white elders, and to examine associations of obesity indices with the presence of type 2 diabetes. Research Methods and Procedures:We examined the prevalence of overweight, obesity, and central obesity in 596 Hispanics of Caribbean origin, ages 60 to 92 years, and 239 non-Hispanic whites, and tested linear and logistic regression models to determine associations among body mass index (BMI), waist circumference (WC), and diabetes. Results: Obesity (BMI Ն 30 kg/m 2 ) was prevalent among all ethnic groups, ranging from 17% to 29% for Dominican and Puerto Rican men, respectively, and from 29% to 40% for non-Hispanic white and Dominican women, respectively. These differences were not statistically significant. Among Hispanic men and women, diabetes was prevalent across all BMI and WC categories but tended to be greatest among those with BMI of 25 to 29 kg/m 2 (41% to 43%). In contrast, diabetes was most prevalent in the obese group (36% to 45%) of non-Hispanic whites. Both BMI and WC were associated with the presence of diabetes, but the coefficients were greater for non-Hispanic whites than for Hispanics. Discussion: Caribbean Hispanics and non-Hispanic whites living in the same Massachusetts localities had high prevalences of overweight and obesity. Total and central obesity exerted a differential effect on the presence of diabetes among ethnic groups; for Hispanics, diabetes was prevalent even among non-obese individuals, whereas for non-Hispanic white women, the prevalence of diabetes was strongly associated with total and central obesity. Additional research is needed to investigate the factors associated with the differential effect of obesity on the prevalence of type 2 diabetes among Hispanic and non-Hispanic white elders.

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Some health benefits of physical activity. The Framingham Study

Cited by 347 publications

References 0 publications

The duration of obesity and the risk of type 2 diabetes

The duration of obesity and the risk of type 2 diabetes

Prior Exercise Increases Dietary Oleate, but Not Palmitate Oxidation

Total and Central Obesity among Elderly Hispanics and the Association with Type 2 Diabetes

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