Some novel hexa‐coordinated cadmium Schiff base complexes: X‐ray structure, Hirshfeld surface analysis, antimicrobial and thermal analysis

Abstract

A series of cadmium (II) complexes with the general formula of CdLX2, where X = Cl−, Br−, I−, SCN− and N3− and L is a tetradentate N4‐donor Schiff base ligand; were synthesized by a sonochemical process as a simple, cost effective and environmentally friendly method. The organic ligand was obtained by condensation reaction of triethylenetetraamine (trien) and cinnamaldehyde. The characterization of coordination compounds was carried out by FT‐IR, 1HNMR, 13CNMR, UV–visible spectroscopies and then conductivity measurements. The crystal structure of the cadmium azide complex was determined by single crystal X‐ray diffraction. This complex crystallizes in the monoclinic space group of C2/c. The cadmium ion is hexa‐coordinated by four nitrogen atoms from the tetradendate Schiff base ligand and two terminal azide nitrogen atoms. The crystal packing and Hirshfeld surface analysis of the CdL(N3)2 complex indicates the essential role of intermolecular interactions related to azido groups in the formation of supramolecular structure. The thermal behavior of complexes was studied by TG/DTG analysis. Moreover, an antibacterial bioassay of the cadmium complexes has been performed in vitro against two gram‐positive (Staphylococcus aureus and Bacillus subtilis) and two gram‐negative (Escherichia coli and Pseudomonas aeruginosa) bacterial strains. Furthermore antifungal activities of the compounds against two fungal strains of Aspergilus niger and Candida albicans were also investigated.

Novel flame retardant paint based on Co(II) and Ni(II) metal complexes as new additives for surface coating applications

“…Moreover, ligand (IAAP) have shown sharp band at 3,456 cm −1 which are the characteristic features of the –NH of isatin molecule. [ 40 ] Owing to the hydrated nature of the complexes, it is difficult to observe the absence and the presence of the (–NH) of the isatin molecule in all the complexes. The presence of the band around 3,400 cm −1 in the complexes of Co(II) and Ni(II) complexes is the indication of coordinated/lattice celled water molecule.…”

Synthesis, Characterization, and Antibacterial Evaluation of Heteroleptic Oxytetracycline-Salicylaldehyde Complexes

“…However, the parent drug oxytetracycline has shown a greater inhibitory effect relative to complexes. Moreover, the growth inhibitory effect is greater at higher concentrations of the complexes [49,50]. Antibacterial potency of the complexes is based on the chelation theory.…”

Computational studies, antimicrobial activity, inhibition of biofilm production, and safety profile of the cadmium complex of 1,10‐phenanthroline and cyanoguanidine

“…Moreover, the [Cd(1‐[[3‐methyl‐pyridine‐2‐ylimino]‐methyl]‐naphthalen‐2‐ol)Cl] complex showed significant antioxidant activity against DPPH (IC 50 = 138 μg ml −1 ) and antibacterial properties (judged by the diameters of inhibition zones), 20 like the cadmium (II) complex with reduced Schiff bases derived from N , N ′‐ o ‐phenylenebis (salicylideneimine) 21 . Other reports of cadmium based compounds proposed antibacterial and antifungal properties employing preliminary screening techniques based on Kirby‐Bauer's method 22–27 . Few reports of antibiofilm activity of cadmium complexes are available in the literature.…”

“…21 Other reports of cadmium based compounds proposed antibacterial and antifungal properties employing preliminary screening techniques based on Kirby-Bauer's method. [22][23][24][25][26][27] Few reports of antibiofilm activity of cadmium complexes are available in the literature. Likewise, two tetranuclear Cd (II) complexes with salen-type Schiff base ligands showed antibiofilm activity against Enterococcus gallinarum MTCC7049 and Proteus vulgaris MTCC744, 15 whereas the [Cd (sulfamethoxazolate) 2 ] complex showed greater biofilm inhibition (and destruction of already formed biofilm) than the free antibiotic against Mycobacterium fortuitum and Mycobacterium abscessus.…”