Perturbative spectra and related factorization properties of one-loop open string amplitudes in the presence of a constant external background B are analysed in detail. While the pattern of the closed string spectrum, obtained after a careful study of the properly symmetrized amplitudes, turns out to be unaffected by the presence of B, a series of double open-string poles, which would be absent when B is turned off, can couple owing to a partial symmetry loss. These features are studied first in a bosonic setting and then generalized in the more satisfactory superstring context. When the background is of an "electric" type, a classical perturbative instability is produced beyond a critical value of the electric field. In the Seiberg-Witten limit this instability is the origin of the unphysical tachyonic cut occurring in the non-planar amplitudes of the corresponding noncommutative field theories.