“…Moreover, all phytochemicals present in whole extracts may simultaneously modulate different targets of action in both human cells and microorganisms, leading to a mixture of pharmacological effects contributing together to improve a patient's health. Hence, we and other researchers have started investigating the anti-infective action of a number of phytocomplexes in a context of a multitarget pharmacological strategy (Lezama-Davila et al, 2014;Aro et al, 2015;Bisignano et al, 2015;Filocamo et al, 2015b;Filocamo et al, 2015a;Kenny et al, 2015;Khalifa et al, 2015;Pogacar et al, 2015;Bisignano et al, 2013a;Bisignano et al, 2013b).…”