2015
DOI: 10.1002/ptr.5338
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Some South African Rubiaceae Tree Leaf Extracts Have Antimycobacterial Activity Against Pathogenic and Non‐pathogenic Mycobacterium Species

Abstract: Tuberculosis (TB) caused by

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Cited by 31 publications
(38 citation statements)
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“…The findings for predictor of activity against pathogenic Mycobacterium strains amongst the non-pathogenic Mycobacterium strains used in this study are presented in Table 3 (Altaf et al, 2010). In agreement with our study, M. aurum was reported as a better predictor of anti-M. tuberculosis activity by Aro et al (2015). In this study, the highest r value=0.83 was observed with pathothogenic M. bovis and M. tuberculosis.…”
Section: Pru122537supporting
confidence: 88%
“…The findings for predictor of activity against pathogenic Mycobacterium strains amongst the non-pathogenic Mycobacterium strains used in this study are presented in Table 3 (Altaf et al, 2010). In agreement with our study, M. aurum was reported as a better predictor of anti-M. tuberculosis activity by Aro et al (2015). In this study, the highest r value=0.83 was observed with pathothogenic M. bovis and M. tuberculosis.…”
Section: Pru122537supporting
confidence: 88%
“…Also, Amycolatopsis species have previously been reported to contribute to plant health by antibiotic production [57]. The genus Mycobacterium, which contains important human pathogens [58], was also prevalent in rhizosphere soils. This is not surprising, as most of the species of the genus are ubiquitous saprophytes in many environments [59].…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, all phytochemicals present in whole extracts may simultaneously modulate different targets of action in both human cells and microorganisms, leading to a mixture of pharmacological effects contributing together to improve a patient's health. Hence, we and other researchers have started investigating the anti-infective action of a number of phytocomplexes in a context of a multitarget pharmacological strategy (Lezama-Davila et al, 2014;Aro et al, 2015;Bisignano et al, 2015;Filocamo et al, 2015b;Filocamo et al, 2015a;Kenny et al, 2015;Khalifa et al, 2015;Pogacar et al, 2015;Bisignano et al, 2013a;Bisignano et al, 2013b).…”
Section: Introductionmentioning
confidence: 99%