Some subpopulations of lymphocytes in individuals exposed to ionizing radiation in utero

Рыбкина, В. Л.; Sinel’shchikova, O.A.; Ослина, Д. С.; Kirillova, E N; Azizova, Tamara V.; Adamova, Galina; Zhuntova, G.V.

doi:10.33029/0206-4952-2021-42-3-261-269

Cited by 2 publications

(3 citation statements)

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“…Chernobyl cleanup workers (liquidators) underwent regular medical checkups so that detection rates of various diseases were higher among them compared to the general population [24] . Other reports on enhanced risks of non-malignant conditions under the impact of low-dose irradiation [12,13,[25][26][27][28][29][30] have been discussed previously [2,3,11] .…”

Section: Resultsmentioning

confidence: 99%

“…The tendency to overestimate health-related risks from low-dose low-rate exposures to ionizing radiation in publications from the former SU has been noticed in Chernobyl-related studies since the 1990 [42][43][44] and in those from the Urals since the mid-2000s [12,13,[25][26][27][28][29][30] ; commented previously [2,3,11,[45][46][47] . Earlier data by the same and other Russian researchers did not confirm associations of cataracts with doses ≤ 2-4 Gy [48][49][50][51] .…”

Section: Discussionmentioning

confidence: 99%

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Exaggeration of consequences of low-dose radiation exposures with special reference to cataracts

Jargin

2024

Imaging. Radiat. Res.

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Publications overestimating the medical and ecological sequels of a slight anthropogenic increase in the radiation background have been reviewed recently with examples of different organs and pathological conditions. The overestimation contributed to the strangulation of atomic energy. The use of nuclear energy for electricity production is on the agenda today due to the increasing energy needs of humankind. Apparently, certain scientific writers acted in the interests of fossil fuel producers. Health risks and environmental damage are maximal for coal and oil, lower for natural gas, and much lower for atomic energy. This letter is an addition to previously published materials, this time focused on studies of cataracts in radiation-exposed populations in Russia. Selection and self-selection bias are of particular significance. Apparently, the self-reporting rate correlates with dose estimates and/or with professional awareness about radiation-related risks among nuclear workers or radiologic technologists, the latter being associated with their work experience/duration and hence with the accumulated dose. Individuals informed of their higher doses would more often seek medical advice and receive more attention from medics. As a result, lens opacities are diagnosed in exposed people earlier than in the general population. This explains dose-effect correlations proven for the incidence of cataracts but not for the frequency of cataract surgeries. Along the same lines, various pathological conditions are more often detected in exposed people. Ideological bias and the trimming of statistics have not been unusual in the Russian medical sciences. It is known that ionizing radiation causes cataracts; however, threshold levels associated with risks are understudied. In particular, thresholds for chronic and fractionated exposures are uncertain and may be underestimated.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Exaggeration of consequences of low-dose radiation exposures with special reference to cataracts

Jargin

2024

Imaging. Radiat. Res.

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“…Thus, the authors note that the study of people exposed to intrauterine irradiation did not detect abnormalities in the main lymphocyte subpopulations. A tendency to decrease the relative number of lymphocytes expressing the early activation marker CD25 in individuals exposed to intrauterine irradiation was observed as a function of the increase in the total dose of external γ radiation absorbed in the bone marrow during the mother's pregnancy (41).…”

Section: Effects Of Ir On Children Whose Parents Were Irradiatedmentioning

confidence: 97%

Clinical, immunological and genetic research on the participants in mitigating the consequences of the Chernobyl nuclear accident

CORETCHI,

GINCU,

BAHNAREL

et al. 2022

OH&RM

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Introduction. The paper presents the results of research on the influence of IR sources on the health of professionally and accidentally exposed personnel. Particular emphasis is placed on: identifying the relationships between the level of radiation dose and the development of oncological diseases; use of contemporary biological dosimetry methods for retrospective analysis of irradiation doses; the impact of parental irradiation on the health of the offspring; the structure of morbidity, including oncological diseases in patients exposed to IR sources. Material and methods. The study material was used by subjects professionally and accidentally exposed to IR sources: medical staff and PMCCNA born in the Republic of Moldova, Ukraine and the Russian Federation, as well as their descendants, victims of the accident at the Fukushima Daiichi nuclear power plant (Japan) and residents of the region. Chelyabinsk. Clinical, immunological and cytogenetic methods were used. Results. A wide range of mental pathologies was observed at PMCCNA, at the victims of the accident at the Fukushima Daiichi nuclear power plant, etc. The structure of immune deficiency syndromes was dominated by allergic and autoimmune syndromes. Based on the analysis of stable chromosomal aberrations, exposure doses were established. Conclusions. In the absence of dose information received by staff professionally/accidentally exposed to IR sources, assessment of stable chromosomal aberrations makes it possible to reconstruct the radiation dose for PMCCNA exposed to low doses of IR.

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Some subpopulations of lymphocytes in individuals exposed to ionizing radiation in utero

Cited by 2 publications

References 1 publication

Exaggeration of consequences of low-dose radiation exposures with special reference to cataracts

Exaggeration of consequences of low-dose radiation exposures with special reference to cataracts

Clinical, immunological and genetic research on the participants in mitigating the consequences of the Chernobyl nuclear accident

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