Sonochemical Coating of Cotton and Polyester Fabrics with “Antibacterial” BSA and Casein Spheres

Abstract

A novel antibacterial coating for cotton and polyester fabrics has been developed by using drug-loaded proteinaceous microspheres made of bovine serum albumin and casein proteins. The microbubbles were created and anchored onto the fabrics (see figure) in a one-step reaction that lasts 3 min. The sonochemically produced "antibacterial fabrics" have been characterized. The efficiency of the sonochemical process in converting the native proteins into microspheres, encapsulating the drug, and coating the fabric has also been studied.

Bioactive microsphere-based coating for biomedical-textiles with encapsulated antimicrobial peptides (AMPs)

“…The Control samples (cotton gauze without microspheres) did not present any inhibition, as expected (see Table 1). Quite different were the results presented by the samples coated with Alg/CS multilayers in chitosan microspheres, since inhibition rates of 28.33% and 29.00% were obtained against K. pneumoniae and S. aureus, respectively, an antibacterial effect comparable with the qualitative results given by Shimanovih and co-workers [4] since no quantitative average was provided.…”

“…In the above described conditions, the CS microspheres have spherical shape and a size about 2 μm, as it can be seen in the inverted microscopy images and SEM images presented in figure 2. Thus they have the shape and size that are in accordance with the previous results obtained by Shao and co-workers [10] with the advantage of being obtained in a much faster and simple method than the reported by Agnihotri and coworkers [18] who studied the preparation of chitosan nanoparticles by emulsion cross-linking or by Shao and co-workers [10] whereas ultrasonication required 30 min to generate monodisperse CS microspheres with 1 μm size and spherical shape, still a little more time in comparison of the 3 minutes reposted by Shimanovih and co-workers [4], probably due to the difference in using BSA instead of CS, that can provide protein crosslinking through SS bonds. Therefore, in comparison with other methods which used CS as the primer polymer for the microsphere shell formation, the results obtained are promising since they show microspheres with size ± 2 μm through a simple and fast process (only 10 minutes sonication).…”

“…Gouveia) pesticides, pharmaceuticals, medicine, food, etc. but they have been more recently introduced in textile area [3][4][5]. Therefore, controlled release of bioactive substances encapsulated in polymeric microspheres and microcapsules deposited on textiles may be a new strategy that opens new perspectives for applications of textiles.…”

Eco-Friendly Cellulose–Polymer Nanocomposites: Synthesis, Properties and Applications

“…Shimanovich et al [55] developed a sonochemical method to coat tetracyclin, TTCL-loaded proteinaceous microspheres were made of BSA and casein proteins. The authors made TTCL-encapsulated microspheres with proteinaceous proteins and optimised the optimal concentration to coat on the cotton/polyester is 5.4 × 10 −3 M. Dodecane and aq.…”

Nanotechnology solutions to restore antibiotic activity

“…Nanoparticles increase chemical activity due to crystallographic surface structure with their large surface to volume ratio. Another example of usage of "therapeutically safe" components is the use of protein and polysacharides, for antibiotics delivery to achieve desired toxicology characteristics has been reported elsewhere 46,49 . For this reason, the scope of the article will focus on the synthetic approaches for antibiotic-based nanoparticles formation as well as on mechanisms of nanoantibiotics activity and cellular toxicity.…”