Les auteurs remercient, pour leurs commentaires sur une première version de cet article, les participants du séminaire de la Chaire Transition démographique, Transition économique et de la conférence « Évaluation des politiques publiques » (Direction du Trésor/Afse) ainsi qu'Anne Lavigne (Conseil d'orientation des retraites). Nous remercions également les deux rapporteurs anonymes de la revue pour leurs critiques et commentaires particulièrement pertinents. Les auteurs restent évidemment seuls responsables des limites de leur travail.Abstract: This article aims at measuring the net effect of physical and psychosocial working conditions faced during the whole professional career on retirees' self-assessed physical and mental health as well as their drug consumption. Based on the French Health and Professional Route survey, we control our regressions for socioeconomic characteristics, employment, professional route, past individual characteristics at entry on the labour market and also past health status. Our results highlight the negative role of exposures to detrimental working conditions on retirees' physical and mental health with a clear relationship between physical constraints and physical health on the one hand, and between psychosocial risk factors and mental health (including drug consumption) on the other hand. These findings underline the long-term effect of painful working conditions on health status, even after retirement.