Sources of Dengue Viruses Imported into Queensland, Australia, 2002–2010

Abstract

Molecular epidemiologic analysis shows that travelers returning from Asia are the greatest source of risk.

Phylogenetic study reveals co-circulation of Asian II and Cosmopolitan genotypes of Dengue virus serotype 2 in Nepal during 2013

“…The Table 1 Amino acid changes observed in DENV-2 strains of the Asian II and Cosmopolitan genotypes from Nepal compared to New Guinea Strain C reference strain ( observations indicate that these DENV-2 strains might be of exotic introduction into Nepal. The country being a tourist destination, the chances of cross-border transmission of DENV strains cannot be ruled out as shown in many earlier studies from other parts of the world (Zaki et al, 2008;Shu et al, 2009;Jiang et al, 2012;Lee et al, 2012;Warrilow et al, 2012). Also, the DENV-1 strains identified in the recently reported dengue outbreak in Nepal in 2010 have a closer genetic relation to Indian DENV-1 strains (Pandey et al, 2013).…”

The origins of dengue outbreaks in northern Queensland, Australia, 1990–2017

“…Outbreak strains were considered to have been sourced from Collectively, Southeast Asia (including Indonesia, the Philippines and Thailand) was responsible for 40 outbreaks (55%) and continues to be the highest contributor of outbreaks, due to all four DENV serotypes 9 .…”

“…Likely origins of outbreaks were determined following sequence alignment and phylogenetic tree analysis as previously described 8,9 .…”

“…Queensland is vulnerable to outbreaks of dengue viruses (DENVs) and indeed, due to endemic populations of the mosquito vector Aedes aeypti, Likely origins of outbreaks were determined following sequence alignment and phylogenetic tree analysis as previously described 8,9 .…”

“…Queensland is vulnerable to outbreaks of dengue viruses (DENVs) and indeed, due to endemic populations of the mosquito vector Aedes aeypti, Likely origins of outbreaks were determined following sequence alignment and phylogenetic tree analysis as previously described 8,9 .Outbreak strains were considered to have been sourced from a particular region after demonstrating very high percentage sequence identities (99%) and evolutionary relatedness with the strain identified and sequenced from the index case (where available) or clusters of strains (two or more) which were themselves …”